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Published Innovative antiviral defense with new CRISPR tool
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The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.
Published PFAS exposure from high seafood diets may be underestimated
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A study suggests that people with diets high in seafood may face a greater risk of exposure to PFAS -- the family of human-made toxins known as 'forever chemicals' -- than previously thought. The researchers stress the need for more stringent public health guidelines that establish how much seafood people can safely consume to limit their exposure, particularly in coastal areas where seafood is frequently eaten.
Published Oceanographers uncover the vital role of mixing down of oxygen in sustaining deep sea health
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Oceanographers have shown for the first time the important role of the 'mixing down' of oxygen in maintaining healthy conditions in the deep waters.
Published Exoplanets true to size
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A star's magnetic field must be considered in order to correctly determine the characteristics of exoplanets from observations by space telescopes such as Kepler, James Webb, or PLATO. Researchers show that the distribution of the star's brightness over its disk depends on the star's level of magnetic activity. This, in turn, affects the signature of an exoplanet in observational data. The new model must be used in order to properly interpret the data from the latest generation of space telescopes pointed at distant worlds outside our Solar System.
Published Africa's iconic flamingos threatened by rising lake levels
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It is one of the world's most spectacular sights -- huge flocks or 'flamboyances' of flamingos around East Africa's lakes -- as seen in the film Out of Africa or David Attenborough's A Perfect Planet. But new research has revealed how the lesser flamingo is at danger of being flushed out of its historic feeding grounds, with serious consequences for the future of the species.
Published New computer vision tool wins prize for social impact
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A team of computer scientists working on two different problems -- how to quickly detect damaged buildings in crisis zones and how to accurately estimate the size of bird flocks -- recently announced an AI framework that can do both. The framework, called DISCount, blends the speed and massive data-crunching power of artificial intelligence with the reliability of human analysis to quickly deliver reliable estimates that can quickly pinpoint and count specific features from very large collections of images.
Published Researchers identify new genetic risk factors for persistent HPV infections
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Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide. While the immune system usually clears HPV infections, those that persist can lead to cancer, and a new finding suggests that certain women may have a genetic susceptibility for persistent or frequent HPV infections. These genetic variants could raise a woman's risk of getting cervical cancer from a high-risk HPV infection.
Published Beautiful nebula, violent history: Clash of stars solves stellar mystery
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When astronomers looked at a stellar pair at the heart of a stunning cloud of gas and dust, they were in for a surprise. Star pairs are typically very similar, like twins, but in HD 148937, one star appears younger and, unlike the other, is magnetic. New data suggest there were originally three stars in the system, until two of them clashed and merged. This violent event created the surrounding cloud and forever altered the system's fate.
Published First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle
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Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.
Published Brainless memory makes the spinal cord smarter than previously thought
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Researchers have discovered the neural circuitry in the spinal cord that allows brain-independent motor learning. The study found two critical groups of spinal cord neurons, one necessary for new adaptive learning, and another for recalling adaptations once they have been learned. The findings could help scientists develop ways to assist motor recovery after spinal cord injury.
Published New approach for combating 'resting' bacteria
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Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules called polyphosphates (polyP) are needed for bacteria to slow down movements within cells and let them enter this resting state.
Published 'Surprising' hidden activity of semiconductor material spotted by researchers
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New research suggests that materials commonly overlooked in computer chip design actually play an important role in information processing, a discovery which could lead to faster and more efficient electronics. Using advanced imaging techniques, an international team found that the material that a semiconductor chip device is built on, called the substrate, responds to changes in electricity much like the semiconductor on top of it.
Published Trapped in the middle: Billiards with memory
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Adding one simple rule to an idealized game of billiards leads to a wealth of intriguing mathematical questions, as well as applications in the physics of living organisms. Researchers are discovering the fascinating dynamics of billiards with memory.
Published With inspiration from 'Tetris,' researchers develop a better radiation detector
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A new detector system based on the game 'Tetris' could enable inexpensive, accurate radiation detectors for monitoring nuclear sites.
Published Rock permeability, microquakes link may be a boon for geothermal energy
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Using machine learning, researchers have tied low-magnitude microearthquakes to the permeability of subsurface rocks beneath the Earth, a discovery that could have implications for improving geothermal energy transfer.
Published A new spin on organic shampoo makes it sudsier, longer lasting
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While there's no regulation in the U.S. for what's in organic shampoos, they tend to contain ingredients perceived as safe or environmentally friendly. However, these 'clean' shampoos separate and spoil faster than those made with synthetic stabilizers and preservatives. Now, researchers demonstrate that a simple process -- spinning organic shampoo at high speeds -- improved the final products' shelf lives and ability to clean hair.
Published Nanoscale movies shed light on one barrier to a clean energy future
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New research is shedding light on one barrier to a clean energy future: corrosion. Using nanoscale imaging techniques, researchers have captured high-resolution videos of tiny crystals of ruthenium dioxide -- a key ingredient used to produce clean-burning hydrogen -- as they are eaten away by their acidic environment. The research could pave the way to more durable catalysts and dramatically extend the lifetime of devices needed to turn hydrogen green.
Published Tropical coral-infecting parasites discovered in cold marine ecosystems
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Parasites thought only to infect tropical coral reefs have been discovered in a large variety of creatures in cold marine ecosystems along the Northeast Pacific, according to new research.
Published New AI method captures uncertainty in medical images
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Tyche is a machine-learning framework that can generate plausible answers when asked to identify potential disease in medical images. By capturing the ambiguity in images, the technique could prevent clinicians from missing crucial information that could inform diagnoses.
Published Star Trek's Holodeck recreated using ChatGPT and video game assets
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Star Trek's Holodeck is no longer just science fiction. Using AI, engineers have created a tool that can generate 3D environments, prompted by everyday language.