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Categories: Biology: Biotechnology, Environmental: General

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A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.

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Researchers have developed a novel method of adding polyethylene glycol molecules to engineered groups of messenger RNAs called 'mRNA polyplexes', which enable the cells that receive them to produce specific proteins. This technique allows greater control of the site in the body to which the polyplexes are delivered, significantly advancing the field of therapeutic mRNA technologies, with applications in vaccine development and the treatment of cancer and other diseases.

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Forests could also be potential bulwarks against climate change. But, increasingly severe droughts and wildfires, invasive species, and large insect outbreaks -- all intensified by climate change -- are straining many national forests and surrounding lands in the United States. A report outlines a new approach to forest stewardship that 'braids together' Indigenous knowledge and Western science to conserve and restore more resilient forestlands.

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A research team has developed a broadband UV dual-comb spectrometer with which air pollutants can be continually measured and their reaction with the environment can be observed in real time.

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Researchers decode repair mechanism during transcription of genetic information.

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Forensic and environmental experts have teamed up to develop a new scientific method to pinpoint microplastic pollution 'hotspots' in open waters.

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A survey of orchid bees in the Brazilian Amazon, carried out in the 1990s, is shedding new light the impact of deforestation on the scent-collecting pollinators, which some view as bellwethers of biodiversity in the neotropics.

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A study has analyzed the impact of the rise in sea surface temperature on macroalgae communities over the last four decades. Points at various depths were investigated in a location off the coast of Biscay, and an increasing scarcity was observed in the number of cold-affinity structuring species, while small warm-affinity ones have proliferated. The researchers are warning that some ecological functions are in jeopardy as a result.

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An extensive review of current research incorporating geomorphology, hydrology, biogeochemistry, ecology and Indigenous knowledges identifies prevailing factors that shape water and energy flows in Australia's non-perennial rivers -- but the review also points to research deficiencies that must be addressed if these river systems are to be preserved and protected.

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Engineered bacteria can produce a plastic modifier that makes renewably sourced plastic more processable, more fracture resistant and highly biodegradable even in sea water. The development provides a platform for the industrial-scale, tunable production of a material that holds great potential for turning the plastic industry green.

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Wirelessly connected devices perform an expanding array of applications, such as monitoring the condition of machinery and remote sensing in agricultural settings. These applications hold much potential for improving the efficiency, but how do you power these devices where reliable electrical sources are not available? Research points to a possible solution in the form of a novel type of battery.

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Microplastic particles can be found in the most remote ocean regions on earth. In Antarctica, pollution levels are even higher than previously assumed.

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Fish and invertebrate animals are far more affected by warmer and more acidic seawater than was previously known. The big gain of the new method is that more details become known about effects of climate change on species.

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Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.

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Scientists are using computer simulations and laboratory experiments to see if depleted oil and natural gas reservoirs can be used for storing carbon-free hydrogen fuel. Hydrogen is an important clean fuel: It can be made by splitting water using solar or wind power, it can be used to generate electricity and power heavy industry, and it could be used to power fuel-cell-based vehicles. Additionally, hydrogen could be stored for months and used when energy needs outpace the supply delivered by renewable energy sources.

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Worldwide over the past 35 years, dams and land reclamation activities converted 250,000 acres of estuary -- an area roughly 17 times the size of Manhattan -- to urban land or agricultural fields, with most land conversion and estuary loss in rapidly developing countries, a new study finds. The findings could help developing countries avoid problems faced by countries that have already lost or degraded their estuaries.

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With climate change and rising urbanization, the likelihood and severity of urban flooding are increasing. But not all city blocks are created equal. Researchers investigated how urban layout and building structures contribute to pedestrian safety during flooding. Based on their simulated results, the team recommends modifying building corners and protective block layouts to reduce pedestrian risk.

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Researchers have compiled a detailed catalogue of bacteria living in cancer metastases. Having analyzed over 4000 tumors, they shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings. For example, certain bacteria were linked to a worse response to immunotherapy. This study paves the way to a better understanding of how bacteria help or hinder cancer (therapy), and how we can use this for patients' advantage.

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Common 'hard' coastal defenses, like concrete sea walls, might struggle to keep up with increasing climate risks. A new study shows that combining them with nature-based solutions could, in some contexts, create defenses which are better able to adapt.

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Carbon monoxide emissions from industrial production have serious consequences for human health and are a strong indicator of overall air pollution levels. Many countries aim to reduce their emissions, but they cannot control air flows originating in other regions. A new study looks at global flows of air pollution and how they relate to economic activity in the global supply chain.