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Categories: Biology: Biochemistry, Environmental: General

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Malaria is one of the most widespread and deadly infectious diseases worldwide. New compounds are continuously required due to the risk of malaria parasites becoming resistant to the medicines currently used. A team of researchers has now combined the anti-malaria drug artemisinin with coumarin, which, like artemisinin, is also found in plants, and developed an auto-fluorescent compound from both bioactive substances.

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Worldwide, coastal river deltas are home to more than half a billion people, supporting fisheries, agriculture, cities, and fertile ecosystems. In a unique study covering 49 deltas globally, researchers have identified the most critical risks to deltas in the future. The research shows that deltas face multiple risks, and that population growth and poor environmental governance might pose bigger threats than climate change to the sustainability of Asian and African deltas, in particular.

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Researchers think that a flavanol found naturally in red wines can interfere with the proper metabolism of alcohol and can lead to a headache.

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Innovative aquaculture system turns waste wood into nutritious seafood. Researchers hoping to rebrand a marine pest as a nutritious food have developed the world's first system of farming shipworms, which they have renamed 'Naked Clams'.

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The microbiome (the symbiotic community of microbial organisms of a host) is of existential importance for the functioning of every plant and animal, including human beings. A research team has now used the example of the sea anemone Nematostella vectenis to investigate how the microbiome develops together with the host. The researchers describe that the bacterial community is primarily controlled by the host organism during the early stages of life, while bacteria-bacteria interactions play the lead role in subsequent development.

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Biological materials are made of individual components, including tiny motors that convert fuel into motion. This creates patterns of movement, and the material shapes itself with coherent flows by constant consumption of energy. Such continuously driven materials are called 'active matter'. The mechanics of cells and tissues can be described by active matter theory, a scientific framework to understand shape, flows, and form of living materials. The active matter theory consists of many challenging mathematical equations. Scientists have now developed an algorithm, implemented in an open-source supercomputer code, that can for the first time solve the equations of active matter theory in realistic scenarios. These solutions bring us a big step closer to solving the century-old riddle of how cells and tissues attain their shape and to designing artificial biological machines.

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Researchers have determined the gene mutation responsible for an observable trait in bison -- albinism.

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Wild caviar, a pricey delicacy made from sturgeon eggs, has been illegal for decades since poaching brought the fish to the brink of extinction. Today, legal, internationally tradeable caviar can only come from farmed sturgeon, and there are strict regulations in place to help protect the species. However, by conducting genetic and isotope analyses on caviar samples from Bulgaria, Romania, Serbia, and Ukraine -- nations bordering the remaining wild sturgeon populations -- a team of sturgeon experts found evidence that these regulations are actively being broken. Their results show that half of the commercial caviar products they sampled are illegal, and some don't even contain any trace of sturgeon.

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New research  paints an uncharacteristically upbeat picture for the planet. This is because more realistic ecological modelling suggests the world's plants may be able to take up more atmospheric CO2 from human activities than previously predicted.

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After a massive cyclone transformed the ecosystem of Gorongosa National Park, researchers studied the immediate and knock-on impacts to garner lessons for wildlife managers around the world.

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Researchers have uncovered startling connections between micronutrient deficiencies and the composition of gut microbiomes in early life that could help explain why resistance to antibiotics has been rising across the globe. The team investigated how deficiencies in crucial micronutrients such as vitamin A, B12, folate, iron, and zinc affected the community of bacteria, viruses, fungi and other microbes that live in the digestive system. They discovered that these deficiencies led to significant shifts in the gut microbiome of mice -- most notably an alarming expansion of bacteria and fungi known to be opportunistic pathogens. Importantly, mice with micronutrient deficiencies also exhibited a higher enrichment of genes that have been linked to antibiotic resistance.

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Bio-based plastics often end up in recycling streams because they look and feel like conventional plastic, but the contamination of these compostable products makes it much harder to generate functional material out of recycled plastic. Scientists have now developed a biology-driven process to convert these mixtures into a new biodegradable material that can be used to make fresh products. The scientists believe the process could also enable a new field of biomanufacturing wherein valuable chemicals and even medicines are made from microbes feeding off of plastic waste.

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For over 20 years, a research team has studied the common bluetail damselfly. Females occur in three different color forms -- one with a male-like appearance, something that protects them from mating harassment. In a new study, an international research team found that this genetic color variation that is shared between several species arose through changes in a specific genomic region at least five million years ago.

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Old people who follow a Mediterranean diet are at a lower risk of cognitive decline, according to a new study. The study provides new evidence for a better understanding of the biological mechanisms related to the impact of the diet on cognitive health in the aging population.

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The remarkable proton and oxide-ion (dual-ion) conductivities of hexagonal perovskite-related oxide Ba7Nb3.8Mo1.2O20.1 are promising for next-generation electrochemical devices. The unique ion-transport mechanisms they unveiled will hopefully pave the way for better dual-ion conductors, which could play an essential role in tomorrow's clean energy technologies.

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Unlike humans, zebrafish can completely regenerate their hearts after injury. They owe this ability to the interaction between their nervous and immune systems, as researchers now report.

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CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout. The ability to study cells concurrently offers unprecedented insights into new cell types, disease states or other conditions.   While CITE-seq solves the problem of detecting a limited number of proteins while using single-cell sequencing in an unbiased way, one of its limitations is the high levels of background noise that can hinder analysis.

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Algae living within the soft tissue of coral supply much of the energy needed by their hosts, and some symbiotic algae help coral withstand warmer water better than others. Researchers have now found that there was a tradeoff for corals dominated by the thermally sensitive algae -- they have higher growth, but only in cooler water.

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Researchers have rediscovered and successfully cultivating Rhabdamoeba marina -- a rare marine amoeba that has only been reported in two cases in the past century. Using this culture strain, they performed a comprehensive analysis of its genetic sequence, revealing for the first time the phylogenetic position of this enigmatic amoeba, and proposed a novel taxonomic classification based on their research findings.

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A scientists has sulfur on her mind. The yellow element is a vital macronutrient, and she's trying to understand how it cycles through the environment. Specifically, she's curious about the sulfur cycle in Earth's ancient ocean, some 3 billion years ago.