Showing 20 articles starting at article 1561

< Previous 20 articles        Next 20 articles >

Categories: Biology: Microbiology, Offbeat: Space

Return to the site home page

     (via sciencedaily.com)     Original source 

A classic movie was once promoted with the punchline: 'In space, no one can hear you scream'. Physicists have now demonstrated, to the contrary, that in certain situations sound can be transmitted strongly across a vacuum region!

     (via sciencedaily.com)     Original source 

Breastfeeding has long been used as a method to help keep newborns healthy and protected against a variety of diseases. But certain sugars naturally found in breastmilk could also help prevent infections before a baby arrives. Researchers have found that these sugars can stop a common prenatal infection in human tissues and pregnant mice. This could someday help people avoid preterm births or complications without the need for additional antibiotics.

     (via sciencedaily.com)     Original source 

Two oral drugs, molnupiravir and paxlovid (nirmatrelvir/ritonavir), provide equivalent therapeutic benefit in preventing severe COVID-19 in animal models, but only molnupiravir efficiently blocked SARS-CoV-2 transmission when administered at a human effect size-equivalent dose, according to a new study.

     (via sciencedaily.com)     Original source 

The drug tecovirimat is currently in use for the treatment of mpox -- the disease caused by monkeypox virus -- that spread worldwide in 2022. Tecovirimat is an anti-poxviral drug, and its use is driving the emergence of drug-resistant variants of the monkeypox virus. Scientists have identified how monkeypox virus exploits a cellular protein to evade host defenses, allowing it to replicate and spread better. Existing drugs -- developed to treat other viral infections -- also target this cellular protein. When tested against a range of poxviruses, including monkeypox, these drugs were found to have antiviral effects in all cases.

     (via sciencedaily.com)     Original source 

Concentrations of potentially harmful chemical compounds in dust collected from air filtration systems on the International Space Station (ISS) exceed those found in floor dust from many American homes, a new study reveals.

     (via sciencedaily.com)     Original source 

Some HIV-1 carriers who have received an early antiretroviral treatment during several years are able to control the virus for a long term after treatment interruption. However, the mechanisms enabling this post-treatment control have not been fully elucidated. Scientists have now investigated and revealed how neutralizing antibodies, including those described as broadly neutralizing, contribute to virus control. A clinical trial involving the use of broadly neutralizing antibodies should begin in France before the end of 2023.

     (via sciencedaily.com)     Original source 

Fungal infections are killing thousands of Americans each year, some with a morbidity rate of nearly 80%. To make matters worse, only a handful of antifungal treatments are available, and even those are becoming less effective as fungi become more resistant. However, researchers recently published findings indicating that a novel breakthrough treatment may have been discovered.

     (via sciencedaily.com)     Original source 

Epstein-Barr virus (EBV) infection is known to convert resting B lymphocytes into immortal cells that continuously multiply, leading to posttransplant lymphoproliferative disorder (PTLD). Researchers have now uncovered the molecular mechanisms of this growth transformation, demonstrating the crucial role of the cancer-related gene IMPDH2 and nucleolar enlargement. Additionally, the research revealed strong evidence supporting the efficacy of mycophenolate mofetil, an approved immunosuppressant, in inhibiting PTLD, highlighting its therapeutic significance.

     (via sciencedaily.com)     Original source 

Bacteria make up more than 10% of all living things but until recently we had little realization that, as in humans, soil bacteria have internal clocks that synchronize their activities with the 24-hour cycles of day and night on Earth. New research shows just how complex and sophisticated these bacterial circadian clocks are, clearing the way for an exciting new phase of study.

     (via sciencedaily.com)     Original source 

Researchers have discovered a previously unknown mechanism by which bacteria share their genetic material through virus parasites. The insights could help scientists to better understand how bacteria rapidly adapt and evolve, and how they become more virulent and resistant to antibiotics.

     (via sciencedaily.com)     Original source 

Hospital-acquired infections are often hard to treat because the corresponding pathogens become increasingly resistant against antibiotics. The bacterium Acinetobacter baumannii is particularly feared, and there is great pressure to devise novel therapeutic approaches to combat it. Bioinformaticians have now detected an unexpectedly wide diversity of certain cell appendages in A. baumannii that are associated with pathogenicity. This could lead to treatment strategies that are specifically tailored to a particular pathogen.

     (via sciencedaily.com)     Original source 

In temperate climates, like North America and Europe, flu season starts in the fall, peaks in the winter and ends in the spring. While public health officials have generally assumed that influenza is also seasonal in tropical climates, new research has found little evidence of a repeatable pattern in influenza cases in Vietnam. The findings suggest that influenza is likely unpredictable throughout the tropics, posing substantial challenges for prevention and management of cases for the one-third of the global population living in tropical areas.

     (via sciencedaily.com)     Original source 

Four years ago, a report that a common species of fungus might fuel pancreatic cancer offered a promising new view of the deadly disease. But in working to validate the finding, researchers have found no such association.

     (via sciencedaily.com) 

A new image of the galaxy cluster known as 'El Gordo' is revealing distant and dusty objects never seen before, and providing a bounty of fresh science. The infrared image displays a variety of unusual, distorted background galaxies that were only hinted at in previous Hubble Space Telescope images.

     (via sciencedaily.com)     Original source 

A study on almost four thousand people of African descent has identified a gene that acts as natural defense against HIV by limiting its replication in certain white blood cells. This research paves the way for new treatment strategies and underscores the importance of studying diverse ancestral populations to better address their specific medical needs and global health disparities.

     (via sciencedaily.com)     Original source 

A team of scientists has made an important breakthrough in the fight against RNA viruses that cause human diseases and pandemics.

     (via sciencedaily.com)     Original source 

Antiviral therapies are notoriously difficult to develop, as viruses can quickly mutate to become resistant to drugs. But what if a new generation of antivirals ignores the fast-mutating proteins on the surface of viruses and instead disrupts their protective layers?

     (via sciencedaily.com)     Original source 

The availability, speed and effectiveness of genomic sequencing increased dramatically during the pandemic, as scientists worldwide rushed to find ways to track and predict the virus's movement and evolution. It also was critical in the development of effective vaccines. Biologists argue that building on this momentum is critical in society's response to future pandemics, but it requires significant collaboration and investment now, before the next pathogen is threatening society.

     (via sciencedaily.com)     Original source 

Researchers have discovered a new way to attack fungal infections. The key is to block fungi from being able to make fatty acids, the major component of fats. Resistance to anti-fungal drugs is increasing and this new approach will be particularly useful because it works in a new way and affects a broad range of fungal species.

     (via sciencedaily.com)     Original source 

Earth is rapidly warming and scientists are developing a variety of approaches to reduce the effects of climate change. An astronomer has proposed a novel approach -- a solar shield to reduce the amount of sunlight hitting Earth, combined with a tethered, captured asteroid as a counterweight. Engineering studies using this approach could start now to create a workable design that could mitigate climate change within decades.