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Categories: Biology: Microbiology, Offbeat: Space
Published Malaria: Treatment of Plasmodium falciparum malaria patients under threat in the Horn of Africa
(via sciencedaily.com) Original source Diagnosis of Plasmodium falciparum malaria using rapid diagnostic tests and treatment with artemisinin derivatives, the main component of the malaria treatments recommended by the World Health Organization (WHO), are under threat in the Horn of Africa. Scientists have detected the emergence and spread in Eritrea of parasites with both artemisinin resistance and genome modifications that prevent their detection with rapid diagnostic tests, thereby jeopardizing malaria control and elimination campaigns in the region and potentially elsewhere in Africa.
Published Polyps as pixels: Innovative technique maps biochemistry of coral reefs
(via sciencedaily.com) Original source Using an innovative new approach to sampling corals, researchers are now able to create maps of coral biochemistry that reveal with unprecedented detail the distribution of compounds that are integral to the healthy functioning of reefs.
Published An advance in cryo-EM could be a significant boon for research on potential cancer therapies
(via sciencedaily.com) Original source A technology called cryo-electron microscopy enables scientists to see the atomic structure of biological molecules in high resolution. But to date, it has been ineffective for imaging small molecules. A team of biochemists devised a solution that makes it possible to hold small protein molecules in place while they're being imaged, which will enable cryo-EM to produce much clearer images of such molecules. The advance is significant because small and medium-sized protein molecules are an area of focus in research on potential new drugs for cancer and other diseases.
Published Capturing CO2 with electricity: A microbial enzyme inspires electrochemistry
(via sciencedaily.com) Original source Humanity continuously emits greenhouse gases and thereby worsens global warming. Increasing research efforts go into developing strategies to convert these gases, such as carbon dioxide (CO2), into valuable products. CO2 accumulates dramatically over the years and is chemically very stable, thus challenging to transform. Yet, for billions of years, some microbes have actively captured CO2 using highly efficient enzymes. Scientists have now isolated one of these enzymes. When the enzyme was electronically branched on an electrode, they observed the conversion of CO2 to formate with perfect efficiency. This phenomenon will inspire new CO2-fixation systems because of its remarkable directionality and rates.
Published Sperm swimming is caused by the same patterns that are believed to dictate zebra stripes
(via sciencedaily.com) Original source Patterns of chemical interactions are thought to create patterns in nature such as stripes and spots. This new study shows that the mathematical basis of these patterns also governs how sperm tail moves.
Published Tiny CRISPR tool could help shred viruses
(via sciencedaily.com) Original source Scientists mapped out the three-dimensional structure of one of the smallest known CRISPR-Cas13 systems then used that knowledge to modify its structure and improve its accuracy.
Published Novel bacterial proteins from seafloor shine light on climate and astrobiology
(via sciencedaily.com) Original source Researchers have unveiled a remarkable discovery: the identification of novel bacterial proteins that play a vital role in the formation and stability of methane clathrates, which trap gigatons of greenhouse gas beneath the seafloor. These newfound proteins not only suppress methane clathrate growth as effectively as toxic chemicals used in drilling but also prove to be eco-friendly and scalable. This innovative breakthrough not only promises to enhance environmental safety in natural gas transportation but also sheds light on the potential for similar biomolecules to support life beyond Earth.
Published Down goes antimatter! Gravity's effect on matter's elusive twin is revealed
(via sciencedaily.com) For the first time, in a unique laboratory experiment at CERN, researchers have observed individual atoms of antihydrogen fall under the effects of gravity. In confirming antimatter and regular matter are gravitationally attracted, the finding rules out gravitational repulsion as the reason why antimatter is largely missing from the observable universe.
Published Researchers discover disease-causing stem cells in lungs of cystic fibrosis patients
(via sciencedaily.com) Original source Experts in cloning and stem cell science are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis, and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.
Published A close-up of biological nanomachines: Researchers take a deep look at peroxisomal processes
(via sciencedaily.com) The cell organelles known as 'peroxisomes' dispose toxic substances and fats in the human body, among other things, and, in doing so, they prevent serious illnesses. The 'Pex' group of proteins (peroxisomes biogenesis factors) keep these 'detox units' functioning properly -- and now researchers have shown, at the atomic level, how these highly complex processes proceed.
Published Decreasing biodiversity may promote spread of viruses
(via sciencedaily.com) Original source How are environmental changes, loss of biodiversity, and the spread of pathogens connected? The answer is a puzzle. Researchers have now described one piece of that puzzle, showing that the destruction of tropical rainforests harms the diversity of mosquito species. At the same time, more resilient species of mosquitoes become more prevalent -- which also means the viruses they carry are more abundant. If there are many individuals of a given species, those viruses can spread quickly.
Published Genetically engineering associations between plants and nitrogen-fixing microbes could lessen dependence on synthetic fertilizer
(via sciencedaily.com) Original source Nitrogen is an essential nutrient for plant growth, but the overuse of synthetic nitrogen fertilizers in agriculture is not sustainable. A team of bacteriologists and plant scientists discuss the possibility of using genetic engineering to facilitate mutualistic relationships between plants and nitrogen-fixing microbes called 'diazotrophs.' These engineered associations would help crops acquire nitrogen from the air by mimicking the mutualisms between legumes and nitrogen-fixing bacteria.
Published New insights into the atmosphere and star of an exoplanet
(via sciencedaily.com) A new study of the intriguing TRAPPIST-1 exoplanetary system has demonstrated the complex interaction between the activity of the system's star and its planetary features.
Published Antibiotics can help some bacteria survive for longer
(via sciencedaily.com) Original source Scientists have found a surprising effect of some antibiotics on certain bacteria -- that the drugs can sometimes benefit bacteria, helping them live longer.
Published Hidden supermassive black holes reveal their secrets through radio signals
(via sciencedaily.com) Astronomers have found a striking link between the amount of dust surrounding a supermassive black hole and the strength of the radio emission produced in extremely bright galaxies.
Published By air, rain and land: How microbes return after a wildfire
(via sciencedaily.com) Ecological disturbances like wildfires disrupt microbial communities. Researchers found that dispersal played a pivotal role in re-establishing surface-level communities.
Published Discovery in mosquitoes could lead to new strategy against dengue fever and other mosquito-borne vectors
(via sciencedaily.com) Original source Researchers have made an important finding about Aedes aegypti mosquitoes -- one that could one day lead to better methods for reducing the mosquito-to-human transmission of dengue, yellow fever, Zika, and other harmful and sometimes deadly viruses.
Published New strategies reduce treatment failure in malaria by up to 81%
(via sciencedaily.com) Original source To slow artemisinin resistance and reduce treatment failures, an international research team investigated various drug policy interventions in Rwanda, where artemisinin resistance was first reported in 2020. Among other strategies, the team found that next-generation interventions such as triple ACTs (TACTs) -- which combine an artemisinin derivative with two partner drugs or which use a sequential course of one ACT formulation, followed by a different ACT formulation -- resulted in treatment failure counts that were at least 81% lower.
Published This parasitic plant convinces hosts to grow into its own flesh--it's also an extreme example of genome shrinkage
(via sciencedaily.com) Original source Balanophora shed one third of its genes as it evolved into a streamlined parasitic plant -- an extreme degree of genome shrinkage even among parasites. Along the way this subtropical plant developed the ability to induce the host plant to grow into the parasite's own flesh -- forming chimeric organs that mix host and parasite tissues.
Published Nanoparticles made from plant viruses could be farmers' new ally in pest control
(via sciencedaily.com) Engineers have devised a new solution to control a major agricultural menace, root-damaging nematodes. Using plant viruses, the researchers created nanoparticles that can deliver pesticide molecules to previously inaccessible depths in the soil. This 'precision farming' approach could potentially minimize environmental toxicity and cut costs for farmers.