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Categories: Anthropology: Early Humans, Biology: Microbiology

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Short-chain fatty acids (SCFAs), which are produced by gut bacteria from dietary fiber, regulate our immune system, but the mechanism of their action remains unknown. In a recent study, researchers investigated how SCFAs interact with mast cells, a type of white blood cell that plays a central role in allergic reactions. Their findings and insights could lead to innovative and effective anti-allergy medications, supplements, and diets, paving the way for healthier lives.

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Climate change poses a threat to yields and food security worldwide, with plant diseases as one of the main risks. An international team of researchers has now shown that further spread of the fungal disease wheat blast could reduce global wheat production by 13% until 2050. The result is dramatic for global food security.

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Researchers have developed an innovative material to fight against the spread of pathogens, infections and antimicrobial resistance. Inspired by the substances secreted by mussels to adhere to rocks, it can be used as a coating to protect healthcare fabrics and provides an effective alternative to commonly used materials such as paper, cotton, surgical masks and commercial plasters.

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The developmental regulators that confer the identity of N-fixing root nodules belong to a transcription factor family (LSH) more commonly associated with defining the shapes of stems, flowers and leaves.

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A research findings show that different AOM lineages employ different regulatory strategies for ammonia or urea utilization, thereby minimizing direct competition with one another and allowing for coexistence.

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The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers have now developed a breakthrough tool that overcomes this limitation.

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A new study has analyzed plant spore dispersion at its source, where rain droplets shake flexible leaves to initially disperse pathogens.

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A research group has discovered a novel RNA viral genome from microbes inhabiting a high-temperature acidic hot spring. Their study shows that RNA viruses can live in high-temperature environments (70-80 degrees Celsius), where no RNA viruses have been observed before. In addition to the two known RNA virus kingdoms, a third kingdom may exist.

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A team of researchers has achieved a major breakthrough in genome editing technology. They've developed a cutting-edge method that combines the power of designer-recombinases with programmable DNA-binding domains to create precise and adaptable genome editing tools.

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A new type of E. coli that is both highly infectious and resistant to some antibiotics has been discovered. The newly identified mutation of antibiotic-resistant E. coli is described in a new article. The team suggests that some existing antibiotics called carbapenems will be ineffective against the bacteria.

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Green roofs have become increasingly popular thanks to their benefits related to climate adaptation, mitigation, and urban biodiversity management. But, in the U.S., green roofs are typically planted with non-native plants in sterile soils, and their effectiveness declines over time. A new study finds that managing green roof soil microbes boosts healthy urban soil development, which is a methodology that could be applied to support climate resilience in cities.

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Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.

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Antimicrobial resistance is an urgent and growing global crisis. Researchers are exploring phages, viruses that infect bacteria, as a possible solution. In the new study, researchers successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.

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Archaeologists have debated whether Neanderthals or modern humans made stone tools that are found at sites across northern Europe and date from about 40,000 years ago. A new excavation at one site in Germany turned up 45,000-year-old bone fragments that, when analyzed for mitochondrial DNA, proved to be from Homo sapiens. This is the earliest evidence that modern humans overlapped with Neanderthals in northwest Europe, thousands of years before Neanderthals went extinct.

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During infection, reversible switch permits flexible formation of memory T cells, long-lived blood cells that can remember pathogen encounters and respond upon reinfection.

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New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.

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Scientists have developed a green antibiotic alternative to treat the deadly pathogen Streptococcus iniae in hybrid striped bass, the fourth most farmed finfish in the United States, according to a recent study.

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Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2.

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Researchers are currently developing anti-viral surfaces to decrease the spread of infectious diseases. A recent study found that a resin ingredient is effective against coronaviruses and strongly decreases their infectivity on plastic surfaces.

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New research shows that tomato juice can kill Salmonella Typhi and other bacteria that can harm people's digestive and urinary tract health.