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Categories: Anthropology: Early Humans, Biology: Microbiology
Published Highly accurate test for common respiratory viruses uses DNA as 'bait'
(via sciencedaily.com) 
A new test 'fishes' for multiple respiratory viruses at once using single strands of DNA as 'bait', and gives highly accurate results in under an hour.
Published Madagascar mouse lemur retroviruses are diverse and surprisingly similar to ones found in polar bears or domestic sheep
(via sciencedaily.com) 
Madagascar is home to a unique biodiversity with a large number of endemic species, among those many lemur species, including the mouse lemurs. This diversity is also found in their retroviruses. Biologists analyzed the mouse lemur genome and identified viruses of two classes that represent ancient infections of the mouse lemur germline. The viruses now behave similarly to lemur genes and are thus called endogenous retroviruses (ERVs). It was surprising that some of the identified retroviruses are closely related to viruses found in other, very different mammals such as polar bears or domestic sheep. This suggests an intriguing and complex pattern of host switching of retroviruses, much more complex than previously thought.
Published How sex differences influence lung injury in mice
(via sciencedaily.com)
Original source 
More than 2,500 genes exhibit significant sex differences in expression in mouse alveolar type II cells (AT2s), important for keeping the lungs functioning, potentially explaining sex biases in the prevalence and severity of lung diseases. In particular, very high numbers of X-linked genes escape transcriptional silencing in lung alveolar type 2 (AT2s) cells, researchers report.
Published Developing mucosal vaccines for respiratory viruses
(via sciencedaily.com)
Original source 
Vaccines that provide long-lasting protection against influenza, coronaviruses and respiratory syncytial virus (RSV) have proved exceptionally difficult to develop. Researchers now explore the challenges and outline approaches to improved vaccines.
Published Ethical ancient DNA research must involve descendant communities, say researchers
(via sciencedaily.com) 
The analysis of ancient DNA allows scientists to trace human evolution and make important discoveries about modern populations. The data revealed by ancient DNA sampling can be valuable, but the human remains that carry this ancient DNA are often those of the ancestors of modern Indigenous groups, and some communities have expressed concerns about the ethics of sampling by outside parties. A group of scientists make the case for involvement of descendant communities in all aspects of the research process.
Published Elucidating enzyme gene expression in filamentous fungi for efficient biomass energy production
(via sciencedaily.com) 
A research team analyzed the regulatory mechanisms of carbohydrate-hydrolyzing enzyme production in Aspergillus aculeatus, a filamentous fungus that produces enzymes with an excellent ability to degrade plant biomass. The team found that UDP-glucose 4-epimerase (Uge5), an enzyme known for its involvement in galactose metabolism, also regulates the expression of degrading enzyme genes in A. aculeatus. This is the very first report of Uge5's roles in selective gene expression in response to different types of inducing sugars in filamentous fungi.
Published Smallpox has plagued humans since ancient Egyptian times, new evidence confirms
(via sciencedaily.com)
Original source 
Smallpox was once one of humanity's most devastating diseases, but its origin is shrouded in mystery. For years, scientific estimates of when the smallpox virus first emerged have been at odds with historical records. Now, a new study reveals that the virus dates back 2,000 years further than scientists have previously shown, verifying historical sources and confirming for the first time that the disease has plagued human societies since ancient times.
Published Study reveals average age at conception for men versus women over past 250,000 years
(via sciencedaily.com) 
Using a new method based upon comparing DNA mutation rates between parents and offspring, evolutionary biologists have revealed the average age of mothers versus fathers over the past 250,000 years, including the discovery that the age gap is shrinking, with women's average age at conception increasing from 23.2 years to 26.4 years, on average, in the past 5,000 years.
Published Scientists get fungi to spill their secrets
(via sciencedaily.com) 
Using multiplex base-editing, an approach that simultaneously modifies multiple sites in fungal genomes, chemical and biomolecular engineers coax fungi into revealing their best-kept secrets, ramping up the pace of new drug discovery.
Published 'Jumping genes' help fungus kill salamanders
(via sciencedaily.com) 
A fungus that infects salamanders contains multiple copies of the same 'jumping genes', scientists have discovered.
Published Ethereal color variant of mysterious plant is actually a new species
(via sciencedaily.com) 
It was thought that there was only one species of the ghost-like Monotropastrum humile plant found in woodlands across East and Southeast Asia. In a major new discovery, botanists reveal that a rosy pink colored variant is actually a distinct new species, shaking up our understanding of this unusual-looking genus of plants. This 20-year study emphasizes the importance of combining various analytical methods to fully understand and protect biodiversity.
Published Archaeologists uncover oldest known projectile points in the Americas
(via sciencedaily.com) 
Archaeologists have uncovered projectile points in Idaho that are thousands of years older than any previously found in the Americas, helping to fill in the history of how early humans crafted and used stone weapons.
Published Two fungi work together to kill fig trees, study finds
(via sciencedaily.com) 
Research finds that fungus carried by ambrosia beetles works together with a second fungus to cause fig wilting disease.
Published A deep red, cranberry-tinted lipstick that's also antimicrobial
(via sciencedaily.com) 
Lipstick can be a confidence booster, enhance a costume and keep lips from chapping. But sharing a tube with a friend or family member can also spread infections. To develop a version with antimicrobial properties, researchers have added cranberry extract to the formulation. Their deep red cream quickly inactivates disease-causing viruses, bacteria and a fungus that come in contact with it.
Published Harmful fungal toxins in wheat: a growing threat
(via sciencedaily.com) 
Wheat -- the most widely cultivated crop in the world -- is under growing attack from harmful toxins. Across Europe, almost half of wheat crops are impacted by the fungal infection that gives rise to these toxins, according to a new study.
Published Early humans may have first walked upright in the trees
(via sciencedaily.com) 
Human bipedalism -- walking upright on two legs -- may have evolved in trees, and not on the ground as previously thought, according to a new study.
Published Increasing forest cover in the Eifel region 11,000 years ago resulted in the local loss of megafauna
(via sciencedaily.com) 
Sediment cores obtained from Eifel maar sites provide insight into the presence of large Ice Age mammals in Central Europe over the past 60,000 years: Overkill hypothesis not confirmed. Herds of megafauna, such as mammoth and bison, have roamed the prehistoric plains in what is today's Central Europe for several tens of thousands of years. As woodland expanded at the end of the last Ice Age, the numbers of these animals declined and by roughly 11,000 years ago, they had completely vanished from this region. Thus, the growth of forests was the main factor that determined the extinction of such megafauna in Central Europe.
Published Immune system of modern Papuans shaped by DNA from ancient Denisovans, study finds
(via sciencedaily.com) 
Modern Papuans' immune system likely evolved with a little help from the Denisovans, a mysterious human ancestor who interbred with ancient humans, according to a new study.
Published How intensive agriculture turned a wild plant into a pervasive weed
(via sciencedaily.com) 
Agriculture is driving rapid evolutionary change, not just on farms but also in wild species in surrounding landscapes, new research has found.
Published Jawbone may represent earliest presence of humans in Europe
(via sciencedaily.com) 
For over a century, one of the earliest human fossils ever discovered in Spain has been long considered a Neanderthal. However, new analysis from an international research team dismantles this century-long interpretation, demonstrating that this fossil is not a Neanderthal; rather, it may actually represent the earliest presence of Homo sapiens ever documented in Europe.