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Categories: Anthropology: Early Humans, Biology: Microbiology
Published Humans bite back by deactivating mosquito sperm
(via sciencedaily.com) New research makes it likely that proteins responsible for activating mosquito sperm can be shut down, preventing them from swimming to or fertilizing eggs.
Published Compressive stress shapes the symmetry of Arabidopsis root vascular tissue
(via sciencedaily.com) A cytokinin-mediated, proliferation-based mechanism is involved in the generation and maintenance of cell-type specific tissue boundaries during vascular development in Arabidopsis roots. Specifically, the HANABA-TARANU transcription factor forms a feed-forward loop to cytokinin signaling, which in turn regulates the position and frequency of cell proliferation of proto-vascular cells such that mechanical stress of the surrounding tissues guides growth in an apical-oriented manor, maintaining cell patterning throughout the tissue section.
Published Where the HI-Virus sleeps in the brain
(via sciencedaily.com) The human immunodeficiency virus HIV-1 is able to infect various tissues in humans. Once inside the cells, the virus integrates its genome into the cellular genome and establishes persistent infections. The role of the structure and organization of the host genome in HIV-1 infection is not well understood. Using a cell culture model based on brain immune microglia cells, an international research team has now defined the insertion patterns of HIV-1 in the genome of microglia cells.
Published Cellular waste removal differs according to cell type
(via sciencedaily.com) 'Miniature shredders' are at work in each cell, disassembling and recycling cell components that are defective or no longer required. The exact structure of these shredders differs from cell type to cell type, a study now shows. For example, cancer cells have a special variant that can supply them particularly effectively with building blocks for their energy metabolism.
Published New research establishes how and why Western diets high in sugar and fat cause liver disease
(via sciencedaily.com) New research has established a link between western diets high in fat and sugar and the development of non-alcoholic fatty liver disease, the leading cause of chronic liver disease.
Published Bird flu associated with hundreds of seal deaths in New England in 2022
(via sciencedaily.com) Researchers have found that an outbreak of highly pathogenic avian influenza (HPAI) was associated with the deaths of more than 330 New England harbor and gray seals along the North Atlantic coast in June and July 2022, and the outbreak was connected to a wave of avian influenza in birds in the region.
Published Designing more useful bacteria
(via sciencedaily.com) In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.
Published 'Glow-in-the-dark' proteins could help diagnose viral diseases
(via sciencedaily.com) Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources. But now, a team has developed a sensitive method that analyzes viral nucleic acids in as little as 20 minutes and can be completed in one step with 'glow-in-the-dark' proteins.
Published Neolithic ceramics reveal dairy processing from milk of multiple species
(via sciencedaily.com) A new study has found evidence of cheesemaking, using milk from multiple animals in Late Neolithic Poland.
Published Humans are leaving behind a 'frozen signature' of microbes on Mount Everest
(via sciencedaily.com) Thanks to technological advances in microbial DNA analysis, researchers have discovered that mountaineers' boots aren't the only things leaving footprints on the world's tallest mountain. When someone sneezes on Everest, their germs can last for centuries.
Published Innovative approach opens the door to COVID nanobody therapies
(via sciencedaily.com) The relatively simple and low-cost procedure could empower laboratories in low-resource areas to generate nanobodies against SARS-CoV-2, as well as other viruses.
Published Molecular component of caffeine may play a role in gut health
(via sciencedaily.com) A new study explores exactly what leads to the generation of Th17 cells -- an important subtype of cells in the intestine -- and uncovers some of the underappreciated molecular players and events that lead to cell differentiation in the gut.
Published The 'Rapunzel' virus: an evolutionary oddity
(via sciencedaily.com) Extremely long tail provides structural window into how bacteria-infecting viruses called phages assemble.
Published High winds can worsen pathogen spread at outdoor chicken farms
(via sciencedaily.com) A study of chicken farms in the West found that high winds increased the prevalence of Campylobacter in outdoor flocks, a bacterial pathogen in poultry that is the largest single cause of foodborne illness in the U.S. Researchers found that about 26% of individual chickens had the pathogen at the 'open environment' farms in the study, which included organic and free-range chicken farms. High winds the week prior to sampling and the farms' location in more intensive agricultural settings were linked to a greater prevalence of Campylobacter.
Published The immune system does battle in the intestines to keep bacteria in check
(via sciencedaily.com) Researchers sheds light on a face-off in the intestines between the immune system and a bacterial pathogen whose family members cause gastrointestinal disease and the plague. The team's insights may extend to other chronic infections and could inform the development of immunotherapies capable of fully extinguishing such diseases.
Published Researchers develop new technology to easily detect active TB
(via sciencedaily.com) A team of faculty has discovered new technology that will quickly and easily detect active Mycobacterium tuberculosis (TB) infection antibodies.
Published Scientists transform algae into unique functional perovskites with tunable properties
(via sciencedaily.com) Scientists have transformed single-cell algae into functional perovskite materials. The team has converted mineral shells of algae into lead halide perovskites with tunable physical properties. The new perovskites have unique nano-architectures unachievable by conventional synthetic production. The method can be applied to the mass production of perovskites with tunable structural and electro-optical properties from single-celled organisms.
Published A quick new way to screen virus proteins for antibiotic properties
(via sciencedaily.com) A whole new world of antibiotics is waiting inside the viruses that infect bacteria. Scientists are making it easier to study them.
Published Looking for risky viruses now to get ahead of future pandemics
(via sciencedaily.com) Rather than let the next outbreak take the world by surprise, two virologists say that the scientific community should invest in a four-part research framework to proactively identify animal viruses that might infect humans.
Published Researchers uncover metabolic secrets of anaerobes and identify new strategies to treat c. difficile infections
(via sciencedaily.com) A team of investigators has identified metabolic strategies used by Clostridioides difficile to rapidly colonize the gut. The findings identify methods to better prevent and treat the most common cause of antibiotic-associated diarrhea and healthcare-acquired infections (HAIs). The team's approach has implications for understanding broader aspects of microbial metabolism, including responses to antibiotics, and production of important metabolites.