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Categories: Anthropology: Early Humans, Biology: Microbiology

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Damage in the human genome can be repaired. But this works better in germ cells, sperm and eggs, than in normal body cells. Responsible for this is the DREAM protein complex, which prevents the activation of all available repair mechanisms. A research team has now shown that normal body cells can also be repaired better once this complex has been deactivated. In the long run, the scientists hope to develop better therapies to prevent cancer and aging-associated diseases.

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Scientists have significantly advanced the race to control plant responses to temperature on a rapidly warming planet. Key to this breakthrough is miRNA, a molecule nearly 200,000 times smaller than the width of a human hair.

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Continued warming of the climate would see a rise in the number and spread of potentially fatal infections caused by bacteria found along parts of the coast of the United States. Vibrio vulnificus bacteria grow in warm shallow coastal waters and can infect a cut or insect bite during contact with seawater. The researchers predict that by 2041--2060 infections may spread to encompass major population centers around New York. Combined with a growing and increasingly elderly population, who are more susceptible to infection, annual case numbers could double.

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Mpox -- previously known as 'monkeypox' -- is currently spreading worldwide. Researchers have now identified a compound that could help fight the disease.

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Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. Researchers have now described a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans. These effector memory B cells appear to be poised for a rapid serum antibody response upon secondary challenge one year later.

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For mosquito-borne diseases such as dengue fever, the abundance of the insects in places where people gather has long served as the main barometer for infection risk. A new study, however, suggests that the number of 'hidden' infections tied to a place, or cases of infected people who show no symptoms, is the key indicator for dengue risk.

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An unusually severe form of toxoplasmosis killed four sea otters and could pose a threat to other marine wildlife and humans, finds a new study.

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Researchers have 'hacked' the earliest stages of photosynthesis, the natural machine that powers the vast majority of life on Earth, and discovered new ways to extract energy from the process, a finding that could lead to new ways of generating clean fuel and renewable energy.

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Researchers behind the UK's first pilot public health surveillance system based on analysis of wastewater say that routine monitoring at sewage treatment works could provide a powerful early warning system for the next flu or norovirus epidemic, alerting hospitals to prepare and providing public health agencies with vital health information.

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A mosquito known only by its scientific name, Culex lactator, is the latest to establish in the Sunshine State, according to a new study.

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Beetles are champions at surviving in extremely dry environments. In part, this property is due to their ability to suck water from the air with their rear ends. A new study explains just how. Beyond helping to explain how beetles thrive in environments where few other animals can survive, the knowledge could eventually be used for more targeted and delicate control of global pests such as the grain weevil and red flour beetle.

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Shigellosis, a highly contagious diarrheal disease, is caused by Shigella bacteria circulating in industrializing countries but also in industrialized countries. Scientists who have been monitoring Shigella in France for several years have detected the emergence of extensively drug-resistant (XDR) strains of Shigella sonnei.

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Cultivation and growth of grapevines have strongly influenced European civilizations, but where the grapevine comes from and how it has spread across the globe has been highly disputed so far. In an extensive genome project, researchers have determined its origin and evolution from the wild vine to today's cultivar by analyzing thousands of vine genomes collected along the Silk Road from China to Western Europe.

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Parasitic infections in salmonid fish can increase or decrease their vulnerability to angling, depending on their body condition.

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A new substance has proven useful for treating staphylococcus infections in people with skin lymphoma. This is good news for the patients, but also for the global threat of antibiotics resistance.

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The ability of a cell to divide, to proliferate, is essential for life and gives rise to the formation of complex organisms from a single cell. It also allows the replacement of used cells from a limited number of 'stem' cells, which then proliferate and specialize. In cancer, however, cell proliferation is no longer controlled and becomes chaotic. Researchers have discovered that, in a healthy individual, certain blood immune cells, the monocytes, also have this ability to proliferate, with the aim to replace tissue macrophages, which are essential for the proper functioning of our body.

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Leading edge technology has uncovered secrets about a world-renowned fossil hoard that could offer vital clues about early life on Earth. Researchers who analyzed the 400 million-year-old cache, found in rural north-east Scotland, say their findings reveal better preservation of the fossils at a molecular level than was previously anticipated.

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An international research team produced the first large-scale analysis of more than 400 newly sequenced and existing Omnitrophota genomes, uncovering new details about their biology and behavior.

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It has long been known that viral infections can be more severe in males than females, but the question as to why has remained a mystery -- until possibly now. Researchers have found that female mouse and human Natural Killer cells have an extra copy of an X chromosome-linked gene called UTX. UTX acts as an epigenetic regulator to boost NK cell anti-viral function, while repressing NK cell numbers.

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Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually. A new study suggests that the FDA-approved drug Fomepizole may reduce disease severity in the lungs of mice with some forms of bacterial pneumonia and enhance the efficacy of the antibiotic erythromycin as well.