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Categories: Biology: Marine, Biology: Microbiology
Published Oxygen charge for battling multidrug-resistant pathogens



In antibacterial photodynamic therapy, irradiation is used to produce reactive oxygen species that kill off bacteria. Because it requires external light and oxygen, this method is only suitable for surface infections. A research team has now introduced a molecular 'singlet oxygen battery' that can be 'charged' with reactive oxygen, which it then releases in deep tissue layers to target methicillin-resistant staphylococcus.
Published Images of enzyme in action reveal secrets of antibiotic-resistant bacteria



Advanced microscopy techniques give scientists valuable clues for how to fight an enzyme that is leading to a rise in cases of antibiotic-resistant bacterial infections worldwide.
Published Distribution of genetic information during bacterial cell division


A mathematical model provides new insights into the distribution of genetic information during bacterial cell division
Published Microbial corrosion of iron


Iron is well-known for rusting, but this doesn't just happen on contact with oxygen and water. Some bacteria are also able to able to decompose iron anaerobically in a process referred to as electrobiocorrosion. The sediment-dwelling bacterium Geobacter sulfurreducens uses electrically conductive protein threads for this purpose. They produce magnetite from the iron, which promotes further corrosion in a positive feedback loop.
Published Surprise COVID discovery helps explain how coronaviruses jump species



Unexpected new insights into how COVID-19 infects cells help explain why coronaviruses are so good at jumping from species to species and will help scientists better predict how COVID-19 will evolve.
Published Soil microbiome, Earth's 'living skin' under threat from climate change



Using a novel method to detect microbial activity in biological soil crusts, or biocrusts, after they are wetted, a research team in a new study uncovered clues that will lead to a better understanding of the role microbes play in forming a living skin over many semi-arid ecosystems around the world. The tiny organisms -- and the microbiomes they create -- are threatened by climate change.
Published Evolving elegance: Scientists connect beauty and safeguarding in ammonoid shells



With 350 million years of evolution culminating in almost two centuries of scientific discourse, a new hypothesis emerges. Researchers propose a new explanation for why ammonoids evolved a highly elaborate, fractal-like geometry within their shells. Their analysis shows that the increasing complexity of shell structures provided a distinct advantage by offering improved protection against predators.
Published Variable patient responses to SARS-CoV-2 infection are mimicked in genetically diverse mice



Researchers have created a panel of genetically diverse mice that accurately model the highly variable human response to SARS-CoV-2 infection. The team uncovered differences in the innate immune and regulated proinflammatory responses, the timing and strength of which are associated with disease severity.
Published Malaria vaccine candidate appears safe and produces promising immune response in a cohort of Tanzanian infants



An experimental malaria vaccine appears safe and promotes an immune response in African infants, one of the groups most vulnerable to severe malaria disease. There is currently only one malaria vaccine, 'RTS,S' that is approved by the World Health Organization and offers partial disease protection. However, in the results of the early-stage phase Ib trial, researchers find that targeting RH5 -- a protein that the malaria pathogen Plasmodium falciparum uses to invade red blood cells -- can generate a promising immune response that is most pronounced in an infant cohort.
Published Microplastics found embedded in tissues of whales and dolphins



Microscopic plastic particles have been found in the fats and lungs of two-thirds of the marine mammals in a graduate student's study of ocean microplastics. The presence of polymer particles and fibers in these animals suggests that microplastics can travel out of the digestive tract and lodge in the tissues.
Published Mechanism underlying bacterial resistance to the antibiotic albicidin revealed



A new analysis shows that infectious bacteria exposed to the antibiotic albicidin rapidly develop up to a 1,000-fold increase in resistance via a gene amplification mechanism.
Published Researchers engineer bacteria that can detect tumor DNA



Creating new technologically advanced sensors, scientists have engineered bacteria that detect the presence of tumor DNA in live organisms. Their innovation could pave the way to new biosensors capable of identifying various infections, cancers and other diseases.
Published Gut microbiome can increase risk, severity of HIV, EBV disease



Researchers created a germ-free mouse model to evaluate the role of the microbiome in the infection, replication, and pathogenesis of HIV and the Epstein-Barr virus, the virus that can cause mononucleosis and other serious diseases.
Published Common cold virus linked to potentially fatal blood clotting disorder



A new observation suggests that a life-threatening blood clotting disorder can be caused by an infection with adenovirus, one of the most common respiratory viruses in pediatric and adult patients.
Published Researchers find new pathway for HIV invasion of cell nucleus



A study has identified a new pathway that human immune deficiency virus (HIV) uses to enter the nucleus of a healthy cell, where it can then replicate and go on to invade other cells.
Published Gastrointestinal viruses all but disappeared during COVID -- but surged back two years on



Following the first stay-at-home orders issued in the U.S. to curb the spread of COVID-19, gastrointestinal viruses such as norovirus, rotavirus and adenovirus all but disappeared from California communities, and remained at very low levels for nearly 2 years, according to new research.
Published Synthetic antibiotic could be effective against drug-resistant superbugs



A scientific journey decades in the making has found a new antibiotic strategy to defeat gram-negative bacteria like Salmonella, Pseudomonas and E. coli, the culprits in many urinary tract infections. The synthetic molecule works fast and is durable. It interferes with synthesis of the bacterial outer membrane by jamming an enzyme. When tested against a clinical collection of 285 bacterial strains, including some that were highly resistant to commercial antibiotics, it killed them all.
Published Gray whales feeding along the Pacific Northwest coast are smaller than their counterparts who travel farther to forage



Gray whales that spend their summers feeding off the coast of Oregon are shorter than their counterparts who travel north to the Arctic for food, new research shows.
Published Top fish predators could suffer wide loss of suitable habitat by 2100 due to climate change



A study of 12 species of highly migratory fish predators -- including sharks, tuna, and billfish such as marlin and swordfish -- finds that most of them will encounter widespread losses of suitable habitat and redistribution from current habitats in the Northwest Atlantic Ocean (NWA) and the Gulf of Mexico (GOM) by 2100. These areas are among the fastest warming ocean regions and are projected to increase between 1-6°C (+1-10°F) by the end of the century, a sign of climate-driven changes in marine ecosystems.
Published Sugars in breastmilk could help treat infections, prevent preterm births



Breastfeeding has long been used as a method to help keep newborns healthy and protected against a variety of diseases. But certain sugars naturally found in breastmilk could also help prevent infections before a baby arrives. Researchers have found that these sugars can stop a common prenatal infection in human tissues and pregnant mice. This could someday help people avoid preterm births or complications without the need for additional antibiotics.