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Categories: Biology: Microbiology, Ecology: Extinction
Published Hospital superbugs: Could one vaccine rule them all?
(via sciencedaily.com) Original source A new study shows that a single dose of the vaccine, administered in mouse models, put immune cells into 'Incredible Hulk' mode, providing rapid protection against nine different bacteria and fungi species that lurk in healthcare settings.
Published Avatars to help tailor glioblastoma therapies
(via sciencedaily.com) Original source Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study.
Published Wastewater detects signs of antimicrobial resistance in aged care facilities
(via sciencedaily.com) Original source A new study analyzing wastewater samples from several aged care facilities and retirement homes, has uncovered worrying signs of antimicrobial resistance (AMR), a concerning trend in aged care facilities.
Published Ancient technology turns plant-based cheese into 'something we want to eat'
(via sciencedaily.com) Original source To produce plant-based cheeses that feel and taste like dairy cheese, scientists have their sights set on fermentation. In a new research result, scientists demonstrate the potential of fermentation for producing climate-friendly cheeses that people want to eat.
Published Scientists develop 3D printing method that shows promise for repairing brain injuries
(via sciencedaily.com) Original source Researchers have produced an engineered tissue representing a simplified cerebral cortex by 3D printing human stem cells. When implanted into mouse brain slices, the structures became integrated with the host tissue. The technique may ultimately be developed into tailored repairs to treat brain injuries.
Published Tracking the bacteria behind life-threatening sepsis in premature babies
(via sciencedaily.com) Original source A new study into sepsis in neonatal babies has uncovered the secrets of the bacteria’s success in causing this life-threatening condition. Using genomic sequencing, they have found how certain strains of bacteria that usually live harmlessly on the skin can evade control measures by colonizing babies’ guts. This will provide new ways to control this threat to babies’ health.
Published New pipeline makes valuable organic acid from plants -- saving money and emissions
(via sciencedaily.com) Original source In a breakthrough for environmentally friendly chemical production, researchers have developed an economical way to make succinic acid, an important industrial chemical, from sugarcane. The team has created a cost-effective, end-to-end pipeline for this valuable organic acid by engineering a tough, acid-tolerant yeast as the fermenting agent, avoiding costly steps in downstream processing. Succinic acid is a widely used additive for food and beverages and has diverse applications in agricultural and pharmaceutical products. This same pipeline can be used to produce other industrially important organic acids from crops rather than petroleum-based processes, significantly reducing greenhouse gas emissions.
Published Gut bacteria found in wild wolves may be key to improving domestic dogs' health
(via sciencedaily.com) Original source Gut microbes found in wild wolves may be the key to alleviating a debilitating gastrointestinal condition common to domestic dogs.
Published When cells go boom: Study reveals inflammation-causing gene carried by millions
(via sciencedaily.com) Original source Researchers have found that a genetic change that increases the risk of inflammation, through a process described as ‘explosive’ cell death, is carried by up to 3% of the global population.
Published Metal-loving microbes could replace chemical processing of rare earths
(via sciencedaily.com) Original source Scientists have characterized the genome of a metal-loving bacteria with an affinity for rare earth elements. The research paves the way towards replacing the harsh chemical processing of these elements with a benign practice called biosorption.
Published Viruses dynamic and changing after dry soils are watered
(via sciencedaily.com) Original source Viruses in soil may not be as destructive to bacteria as once thought and could instead act like lawnmowers, culling older cells and giving space for new growth, according to research.
Published Scientists identify evolutionary gateway helping pneumonia bacteria become resistant to antibiotics
(via sciencedaily.com) Original source An evolutionary gateway which helps pneumonia cells become resistant to antibiotics has been discovered.
Published Trivalent vaccine candidate fights measles, mumps, SARS-CoV-2
(via sciencedaily.com) Original source Altered measles and mumps viruses could be used as a platform to create a trivalent COVID-19 vaccine that triggers immunity to multiple variant strains of the SARS-CoV-2 virus, new research in animals suggests.
Published DNA from discarded whale bones suggests loss of genetic diversity due to commercial whaling
(via sciencedaily.com) Original source Commercial whaling in the 20th century decimated populations of large whales but also appears to have had a lasting impact on the genetic diversity of today’s surviving whales, new research shows.
Published Preventing spread of parasitic DNA in our genomes
(via sciencedaily.com) Original source Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.
Published Study on mysterious Amazon porcupine can help its protection
(via sciencedaily.com) Original source A recent study sheds new light on the elusive Roosmalens' dwarf porcupine, a poorly understood neotropical species. After 22 years of relative obscurity, this research uncovers vital information about its distribution, phylogenetics, and potential conservation threats, not only revealing its endemic presence in the Madeira biogeographical province but also expanding its known range in the southern Amazon.
Published A hygiene program for chromosomes
(via sciencedaily.com) Original source Researchers identified and characterized a new cellular compartment in vertebrate cells that might be a precursor of today's eucaryotic nucleus. The study reveals that mammalian cells recognize, cluster, sort and keep extrachromosomal DNA -- like transfected plasmid DNA and endogenous circular DNAs originating from telomeres of the chromosome -- away from chromosomal DNA. That suggests that there is a cell autonomous genome defense system.
Published To prepare for next pandemic, researchers tackle bird flu
(via sciencedaily.com) Original source Researchers have developed an improved way to test potential vaccines against bird flu.
Published Small but mighty new gene editor
(via sciencedaily.com) Original source A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders. The tool is an enzyme, AsCas12f, which has been modified to offer the same effectiveness but at one-third the size of the Cas9 enzyme commonly used for gene editing. The compact size means that more of it can be packed into carrier viruses and delivered into living cells, making it more efficient.
Published Allergy study on 'wild' mice challenges the hygiene hypothesis
(via sciencedaily.com) Original source The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis. Now, an article challenges this hypothesis by showing that mice with high infectious exposures from birth have the same, if not an even greater ability to develop allergic immune responses than 'clean' laboratory mice.