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Categories: Biology: Microbiology, Mathematics: Statistics

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A new study demonstrates that machine-learning strategies can be applied to routinely collected physiological data, such as heart rate and blood pressure, to provide clues about pain levels in people with sickle cell disease.

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Engineers demonstrate how a testing strategy they call 'distanced online testing' can effectively reduce students' ability to receive help from one another in order to score higher on a test taken at individual homes during social distancing.

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An automated computer analysis method designed by Carnegie Mellon University computer scientists makes it possible to track social biases across decades of Bollywood and Hollywood movies.

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Scientists rarely have the historical data they need to see exactly how nodes in a network became connected. But a new article offers hope for reconstructing the missing information, using a new method to evaluate the rules that generate network models.

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By the time children are 3 years old they already have an adult-like preference for visual fractal patterns commonly seen in nature, according to researchers.

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Researchers have developed a computational method that allows them to determine not if an entire imaging picture is accurate, but if any given point on the image is probable, based on the assumptions built into the model.

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Researchers find COVID-19 super-spreading events, in which one person infects more than six other people, are much more frequent than anticipated, and that they have an outsized contribution to coronavirus transmission.

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Researchers have discovered a uniquely quantum effect in erasing information that may have significant implications for the design of quantum computing chips. Their surprising discovery brings back to life the paradoxical 'Maxwell's demo', which has tormented physicists for over 150 years.

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Human prion diseases include Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker disease (GSS). A new study reports a significant advance in the development of mouse models of human prion diseases. The study demonstrates spontaneous formation of disease-relevant, transmissible prion protein assemblies in mice bearing only human forms of the prion protein.

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A professor of biochemistry and molecular biology report an unanticipated role for prion nucleation seeds that enhances their ability to appear and resist curing.

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A 5-minute soak in a 40% solution of household bleach decontaminated stainless steel wires coated with chronic wasting disease (CWD) prions, according to a new study. The scientists used the wires to model knives and saws that hunters and meat processors use when handling deer, elk and moose - all of which are susceptible to CWD.

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Researchers have developed a new gene-targeted approach to study chronic wasting disease in mice, allowing opportunities for research that has not previously existed.

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Some deer are more susceptible to chronic wasting disease that is spreading through herds of white-tailed deer across much of the United States, according to researchers, who have identified a panel of genetic markers that reliably predict which animals are most vulnerable to the contagious neurological disorder.

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Scientists studying the progression of inherited and infectious eye diseases that can cause blindness have found that microglia, a type of nervous system cell suspected to cause retinal damage, surprisingly had no damaging role during prion disease in mice. In contrast, the study findings indicated that microglia might delay disease progression.

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Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein particles often go undetected as they destroy brain tissue, causing memory loss, mobility issues, and ultimately death. Preclinical detection of prions has proven difficult, but new research suggests skin samples hold early signs of prion disease that precede neurologic symptoms.

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A study has confirmed that some vials of a hormone used in discontinued medical treatments contained seeds of a protein implicated in Alzheimer's disease, and are able to seed amyloid pathology in mice.

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A major compound in soil organic matter degrades chronic wasting disease prions and decreases infectivity in mice, according to a new study.

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By the time symptoms of sporadic Creutzfeldt-Jakob disease (sCJD) are typically discovered, death is looming and inevitable. In a new study, researchers report finding tell-tale evidence of the condition's infectious agent in the eyes of deceased sCJD patients, making the eye a potential source for both early CJD detection and prevention of disease transmission.

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The first example of prion strains that replicate independently in vitro and in vivo suggests that strain diversity may be greater than previously thought, according to a new study.

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A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment.