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Categories: Biology: Microbiology, Engineering: Biometric

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The stubborn superbug Clostridium difficile, or C. diff, may have met its match. A esearcher is reporting the first well-controlled study to demonstrate the effectiveness of a new medicine for patients with the debilitating recurrent infection and disease.

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Researchers have developed a sustainable, inexpensive two-step process that can upcycle organic carbon waste -- including lignin, a difficult-to-breakdown material that gives plants their structure. By processing waste through a microbe-driven biorefinery, the researchers turned lignin into carbon sources that could be used in high-value, plant-derived pharmaceuticals and antioxidant nutraceuticals as well as carbon-based nanoparticles for drug or chemical delivery.

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A research team has developed a novel chemical tool to reveal how bacteria adapt to the host environment and control host cells. This tool can be used to investigate bacterial interactions with the host in real-time during an infection, which cannot be easily achieved by other methods.

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Photosynthesis in plants and some bacteria relies on light-harvesting (LH) supramolecules, which come in different structures. So far, these LH molecules have not been artificially prepared. In a recent study, scientists managed to synthesize LH nanorings via self-assembly of chlorophyll derivatives and examined the external conditions that drove their formation. Their findings could help us study artificial photosynthesis and possibly pave the way for novel materials for LH devices like solar cells.

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A new article shows that an experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial. The vaccine could someday be an important tool to respond to Marburg virus outbreaks.

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By repurposing one of the human body's natural cargo transports, a research team has developed a vaccine platform that could curb certain engineering challenges, storage demands and side effects of vaccines that combat HIV epidemics and the COVID-19 pandemic.

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Stem cells have been modified to carry a therapy to treat companion animal patients with late-stage cancer, preserving good quality of life and extending their lives, potentially leading to better understanding of cancer treatments and their use in humans.

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A device provides protection from mosquitoes for an extended period and requires no heat, electricity or skin contact.

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High throughput sequencing (HTS) data is set to improve our knowledge of Physostegia chlorotic mottle virus biology, epidemiology, and genetic diversity.

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A transporter which some bacteria use to recycle fragments of their cell wall has been discovered. Researchers found that the transporter controls resistance to certain kinds of cell-wall targeting antibiotics.

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The World Health Organization (WHO) ranks antibiotic resistance as one of the top ten threats to global health. There is therefore a great need for new solutions to tackle resistant bacteria and reduce the use of antibiotics. A group of researchers are now presenting a new spray that can kill even antibiotic-resistant bacteria, and that can be used for wound care and directly on implants and other medical devices.

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Scientific claims that babies harbor live bacteria while still in the womb are inaccurate, and may have impeded research progress, according to new research/

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A new study suggests a way to re-energize critical killer immune cells that have become exhausted when fighting cancer or chronic viral infections.

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By flagging disease-associated DNA biomarkers, medical professionals can make early diagnoses and provide personalized treatments, but the typical screening methods can be laborious, expensive or limited in scope. Now, a new biosensor could pave the way to accessible and expansive diagnostics.

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Scientists have detailed a lifestyle switch that occurs in marine bacteria, where they change from coexisting with algae hosts in a mutually beneficial interaction to suddenly killing them.

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A new study finds that microorganisms live in richly diverse and interdependent communities in high-temperature geothermal environments in the deep sea. By constructing genomes of 3,635 Bacteria and Archaea from 40 different rock communities, researchers discovered at least 500 new genera and have evidence for two new phyla. Samples from the deep-sea Brothers volcano were especially enriched with different kinds of microorganisms, many endemic to the volcano. The genomic data from this study also showed that many of these organisms depend on one another for survival. Some microorganisms cannot metabolize all of the nutrients they need to survive so they rely on nutrients created by other species in a process known as a 'metabolic handoff.'

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Microplastics -- tiny particles generated as plastics weather and fragment -- pose a growing threat to ecosystem and human health. A new laboratory study shows these threats extend beyond direct physical or chemical impacts, revealing that the presence of microplastics increases the severity of an important viral fish disease.

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Bacteria of the genus Enterobacter are among the most dangerous bacteria associated with hospital infections worldwide. Some of their representatives are highly resistant to commonly used antibiotics, so that the reserve antibiotic colistin is increasingly used as a last resort therapy option. To avoid unnecessary reliance on colistin and risk increasing resistance, bacteria are tested for sensitivity or resistance to colistin before recommending treatment. However, commonly used tests for Enterobacter are not reliable.

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A potent plant toxin with a unique way of killing harmful bacteria has emerged as one of the strongest new antibiotic candidates in decades.

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The bacterium Rhodococcus ruber eats and actually digests plastic.