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Categories: Biology: Microbiology, Chemistry: Inorganic Chemistry
Published A simple and robust experimental process for protein engineering
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A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.
Published Who knew that coprophagy was so vital for birds' survival?
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New research explains how eating feces (known as coprophagy) shapes wild birds' digestive tracts (gut biota), enabling them to absorb lost or deficient nutrients and adjust to seasonal variations in food sources.
Published Scientists find weak points on Epstein-Barr virus
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Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.
Published Spiral wrappers switch nanotubes from conductors to semiconductors and back
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By wrapping a carbon nanotube with a ribbon-like polymer, researchers were able to create nanotubes that conduct electricity when struck with low-energy light that our eyes cannot see. In the future, the approach could make it possible to optimize semiconductors for applications ranging from night vision to new forms of computing.
Published How a natural compound from sea squirts combats cancer
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Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.
Published Maternal obesity may promote liver cancer
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Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major public health concern. It not only affects the health of those who suffer from it, but could also have serious consequences for their offspring. Scientists have studied the impact of maternal obesity on the risk of developing liver disease and liver cancer. Using an animal model, the team discovered that this risk was indeed much higher in the offspring of mothers suffering from obesity.
Published Design rules and synthesis of quantum memory candidates
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In the quest to develop quantum computers and networks, there are many components that are fundamentally different than those used today. Like a modern computer, each of these components has different constraints. However, it is currently unclear what materials can be used to construct those components for the transmission and storage of quantum information.
Published Researchers uncover protein responsible for cold sensation
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Researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.
Published Breakthrough in nanostructure technology for real-time color display
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New groundbreaking technology enables the real-time display of colors and shapes through changes in nanostructures.
Published 'Molecular Rosetta Stone' reveals how our microbiome talks to us
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Researchers have uncovered thousands of previously unknown bile acids, a type of molecule used by our gut microbiome to communicate with the rest of the body.
Published Higher bacterial counts detected in single-serving milks, researchers report
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Scientists have detected higher bacterial counts in commercial, paperboard single-serving containers two weeks after processing than milk packaged in larger containers from the same facilities.
Published Combined microscopy technique catches light-driven polymers in the act
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Researchers have used tip-scan high-speed atomic force microscopy combined with an optical microscope to observe light-induced deformation of azo-polymer films. The process could be followed in real time, and the film patterns were found to change with the polarization of the light source. The observations will contribute to the use of azo-polymers in applications such as optical data storage, and the approach is expected to be useful across materials science and physical chemistry.
Published New study discovers how altered protein folding drives multicellular evolution
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Researchers have discovered a mechanism steering the evolution of multicellular life. They identified how altered protein folding drives multicellular evolution.
Published How surface roughness influences the adhesion of soft materials
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A research team discovers universal mechanism that leads to adhesion hysteresis in soft materials. Through a combination of experimental observations and simulations, the team demonstrated that roughness interferes with the separation process, causing the materials to detach in minute, abrupt movements, which release parts of the adhesive bond incrementally. The findings will make it possible to specifically control the adhesion properties of soft materials through surface roughness and will allow new and improved applications to be developed in soft robotics or production technology in the future.
Published Tiny wireless light bulbs for biomedical applications
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The combination of OLEDs and acoustic antennas creates a light source that could be used for minimally invasive treatment methods.
Published Researchers develop artificial building blocks of life
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For the first time, scientists have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory.
Published Researchers open new leads in anti-HIV drug development, using a compound found in nature
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A team of researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
Published How does a virus hijack insect sperm to control disease vectors and pests?
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A widespread bacteria called Wolbachia and a virus that it carries can cause sterility in male insects by hijacking their sperm, preventing them from fertilizing eggs of females that do not have the same combination of bacteria and virus. A new study has uncovered how this microbial combination manipulates sperm, which could lead to refined techniques to control populations of agricultural pests and insects that carry diseases like Zika and dengue to humans.
Published The Malaria parasite generates genetic diversity using an evolutionary 'copy-paste' tactic
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All modern Plasmodium falciparum, the deadliest malaria parasite in humans, are descendants of one initial infection and so are very closely related, with relatively limited genetic differences. A long-standing mystery in the field has revolved around a very few locations in the P. falciparum genome where there are 'spikes' of mutations -- far more than anywhere else. Researchers have identified two genes in which these unusual mutation spikes result from DNA being copied and pasted from one gene to another.
Published First atom-level structure of packaged viral genome reveals new properties, dynamics
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A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and drug targets researchers report.