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Categories: Biology: Microbiology, Space: General

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The human immunodeficiency virus HIV-1 is able to infect various tissues in humans. Once inside the cells, the virus integrates its genome into the cellular genome and establishes persistent infections. The role of the structure and organization of the host genome in HIV-1 infection is not well understood. Using a cell culture model based on brain immune microglia cells, an international research team has now defined the insertion patterns of HIV-1 in the genome of microglia cells.

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'Miniature shredders' are at work in each cell, disassembling and recycling cell components that are defective or no longer required. The exact structure of these shredders differs from cell type to cell type, a study now shows. For example, cancer cells have a special variant that can supply them particularly effectively with building blocks for their energy metabolism.

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Venus appears to have volcanic activity, according to a new research paper that offers strong evidence to answer the lingering question about whether Earth's sister planet currently has eruptions and lava flows.

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Scientists revealed the discovery of a relict glacier near Mars' equator. Located in Eastern Noctis Labyrinthus at coordinates 7° 33' S, 93° 14' W, this finding is significant as it implies the presence of surface water ice on Mars in recent times, even near the equator. This discovery raises the possibility that ice may still exist at shallow depths in the area, which could have significant implications for future human exploration.

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New research has established a link between western diets high in fat and sugar and the development of non-alcoholic fatty liver disease, the leading cause of chronic liver disease.

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A new study brings scientists one step closer to answering the question of where Earth's water came from.

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Researchers have found that an outbreak of highly pathogenic avian influenza (HPAI) was associated with the deaths of more than 330 New England harbor and gray seals along the North Atlantic coast in June and July 2022, and the outbreak was connected to a wave of avian influenza in birds in the region.

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In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.

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The largest data release of relatively nearby supernovae (colossal explosions of stars), containing three years of data is publicly available via the Young Supernova Experiment (YSE).

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Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources. But now, a team has developed a sensitive method that analyzes viral nucleic acids in as little as 20 minutes and can be completed in one step with 'glow-in-the-dark' proteins.

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A new study has found evidence of cheesemaking, using milk from multiple animals in Late Neolithic Poland.

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The Walking Oligomeric Robotic Mobility System, or WORMS, is a reconfigurable, modular, multiagent robotics architecture for extreme lunar terrain mobility. The system could be used to assemble autonomous worm-like parts into larger biomimetic robots that could explore lava tubes, steep slopes, and the moon's permanently shadowed regions.

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The rare sight of a Wolf-Rayet star -- among the most luminous, most massive, and most briefly detectable stars known -- was one of the first observations made by NASA's James Webb Space Telescope in June 2022. Webb shows the star, WR 124, in unprecedented detail with its powerful infrared instruments. The star is 15,000 light-years away in the constellation Sagittarius.

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Thanks to technological advances in microbial DNA analysis, researchers have discovered that mountaineers' boots aren't the only things leaving footprints on the world's tallest mountain. When someone sneezes on Everest, their germs can last for centuries.

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The relatively simple and low-cost procedure could empower laboratories in low-resource areas to generate nanobodies against SARS-CoV-2, as well as other viruses.

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A new study explores exactly what leads to the generation of Th17 cells -- an important subtype of cells in the intestine -- and uncovers some of the underappreciated molecular players and events that lead to cell differentiation in the gut.

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In an unlikely pairing, a chemist and an astrophysicist applied the tools of statistical mechanics to find similarities in spatial patterns across length scales.

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Extremely long tail provides structural window into how bacteria-infecting viruses called phages assemble.

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A study of chicken farms in the West found that high winds increased the prevalence of Campylobacter in outdoor flocks, a bacterial pathogen in poultry that is the largest single cause of foodborne illness in the U.S. Researchers found that about 26% of individual chickens had the pathogen at the 'open environment' farms in the study, which included organic and free-range chicken farms. High winds the week prior to sampling and the farms' location in more intensive agricultural settings were linked to a greater prevalence of Campylobacter.

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Researchers sheds light on a face-off in the intestines between the immune system and a bacterial pathogen whose family members cause gastrointestinal disease and the plague. The team's insights may extend to other chronic infections and could inform the development of immunotherapies capable of fully extinguishing such diseases.