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Categories: Biology: Microbiology, Space: General

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A technology called cryo-electron microscopy enables scientists to see the atomic structure of biological molecules in high resolution. But to date, it has been ineffective for imaging small molecules. A team of biochemists devised a solution that makes it possible to hold small protein molecules in place while they're being imaged, which will enable cryo-EM to produce much clearer images of such molecules. The advance is significant because small and medium-sized protein molecules are an area of focus in research on potential new drugs for cancer and other diseases.

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Humanity continuously emits greenhouse gases and thereby worsens global warming. Increasing research efforts go into developing strategies to convert these gases, such as carbon dioxide (CO2), into valuable products. CO2 accumulates dramatically over the years and is chemically very stable, thus challenging to transform. Yet, for billions of years, some microbes have actively captured CO2 using highly efficient enzymes. Scientists have now isolated one of these enzymes. When the enzyme was electronically branched on an electrode, they observed the conversion of CO2 to formate with perfect efficiency. This phenomenon will inspire new CO2-fixation systems because of its remarkable directionality and rates.

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Before human research is conducted during commercial spaceflights, it should be 'ethically cleared to launch,' according to a global team of scientists, health policy experts and commercial spaceflight professionals.

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Patterns of chemical interactions are thought to create patterns in nature such as stripes and spots. This new study shows that the mathematical basis of these patterns also governs how sperm tail moves.

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Scientists mapped out the three-dimensional structure of one of the smallest known CRISPR-Cas13 systems then used that knowledge to modify its structure and improve its accuracy.

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Researchers have unveiled a remarkable discovery: the identification of novel bacterial proteins that play a vital role in the formation and stability of methane clathrates, which trap gigatons of greenhouse gas beneath the seafloor. These newfound proteins not only suppress methane clathrate growth as effectively as toxic chemicals used in drilling but also prove to be eco-friendly and scalable. This innovative breakthrough not only promises to enhance environmental safety in natural gas transportation but also sheds light on the potential for similar biomolecules to support life beyond Earth.

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A newly discovered nearby supernova whose star ejected up to a full solar mass of material in the year prior to its explosion is challenging the standard theory of stellar evolution. The new observations are giving astronomers new insight into what happens in the final year prior to a star's death and explosion.

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For the first time, in a unique laboratory experiment at CERN, researchers have observed individual atoms of antihydrogen fall under the effects of gravity. In confirming antimatter and regular matter are gravitationally attracted, the finding rules out gravitational repulsion as the reason why antimatter is largely missing from the observable universe.

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The supermassive black hole at the heart of galaxy M87, made famous by the first picture of a black hole shadow, has yielded another first: the jet shooting out from the black hole has been confirmed to wobble, providing direct proof that the black hole is spinning.

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Experts in cloning and stem cell science are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis, and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

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The cell organelles known as 'peroxisomes' dispose toxic substances and fats in the human body, among other things, and, in doing so, they prevent serious illnesses. The 'Pex' group of proteins (peroxisomes biogenesis factors) keep these 'detox units' functioning properly -- and now researchers have shown, at the atomic level, how these highly complex processes proceed.

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How are environmental changes, loss of biodiversity, and the spread of pathogens connected? The answer is a puzzle. Researchers have now described one piece of that puzzle, showing that the destruction of tropical rainforests harms the diversity of mosquito species. At the same time, more resilient species of mosquitoes become more prevalent -- which also means the viruses they carry are more abundant. If there are many individuals of a given species, those viruses can spread quickly.

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Nitrogen is an essential nutrient for plant growth, but the overuse of synthetic nitrogen fertilizers in agriculture is not sustainable. A team of bacteriologists and plant scientists discuss the possibility of using genetic engineering to facilitate mutualistic relationships between plants and nitrogen-fixing microbes called 'diazotrophs.' These engineered associations would help crops acquire nitrogen from the air by mimicking the mutualisms between legumes and nitrogen-fixing bacteria.

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In a new study, scientists have shown that sweeping molten oceans have a large influence on the observed properties of hot rocky Super-Earths, such as their size and evolutionary path.

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A new study of the intriguing TRAPPIST-1 exoplanetary system has demonstrated the complex interaction between the activity of the system's star and its planetary features.

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Scientists have found a surprising effect of some antibiotics on certain bacteria -- that the drugs can sometimes benefit bacteria, helping them live longer.

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Scientists have discovered a simple and reliable test for signs of past or present life on other planets -- 'the holy grail of astrobiology.' Researchers report that, with 90% accuracy, their artificial intelligence-based method distinguished modern and ancient biological samples from those of abiotic origin.

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Astronomers have found a striking link between the amount of dust surrounding a supermassive black hole and the strength of the radio emission produced in extremely bright galaxies.

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Ecological disturbances like wildfires disrupt microbial communities. Researchers found that dispersal played a pivotal role in re-establishing surface-level communities.

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Researchers have made an important finding about Aedes aegypti mosquitoes -- one that could one day lead to better methods for reducing the mosquito-to-human transmission of dengue, yellow fever, Zika, and other harmful and sometimes deadly viruses.