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Categories: Biology: Molecular, Offbeat: General
Published A new coating method in mRNA engineering points the way to advanced therapies
(via sciencedaily.com) Original source Researchers have developed a novel method of adding polyethylene glycol molecules to engineered groups of messenger RNAs called 'mRNA polyplexes', which enable the cells that receive them to produce specific proteins. This technique allows greater control of the site in the body to which the polyplexes are delivered, significantly advancing the field of therapeutic mRNA technologies, with applications in vaccine development and the treatment of cancer and other diseases.
Published Cockayne syndrome: New insights into cellular DNA repair mechanism
(via sciencedaily.com) Original source Researchers decode repair mechanism during transcription of genetic information.
Published Revolutionary molecular device unleashes potential for targeted drug delivery and self-healing materials
(via sciencedaily.com) Original source In a new breakthrough that could revolutionise medical and material engineering, scientists have developed a first-of-its-kind molecular device that controls the release of multiple small molecules using force.
Published 'Teacher Toads' can save native animals from toxic cane toads
(via sciencedaily.com) Original source Scientists from Macquarie University have come up with an innovative way to stop cane toads killing native wildlife by training goannas to avoid eating the deadly amphibians.
Published Machine learning method reveals chromosome locations in individual cell nucleus
(via sciencedaily.com) Original source Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.
Published Do some mysterious bones belong to gigantic ichthyosaurs?
(via sciencedaily.com) Original source Several similar large, fossilized bone fragments have been discovered in various regions across Western and Central Europe since the 19th century. The animal group to which they belonged is still the subject of much debate to this day. A study could now settle this dispute once and for all: The microstructure of the fossils indicates that they come from the lower jaw of a gigantic ichthyosaur. These animals could reach 25 to 30 meters in length, a similar size to the modern blue whale.
Published Different means to the same end: How a worm protects its chromosomes
(via sciencedaily.com) Original source Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.
Published Engineers design soft and flexible 'skeletons' for muscle-powered robots
(via sciencedaily.com) Original source Engineers designed modular, spring-like devices to maximize the work of live muscle fibers so they can be harnessed to power biohybrid robots.
Published Inexplicable flying fox found in Hydra galaxy cluster
(via sciencedaily.com) Original source High sensitivity radio observations have discovered a cloud of magnetized plasma in the Hydra galaxy cluster. The odd location and shape of this plasma defy all conventional explanations. Dubbed the Flying Fox based on its silhouette, this plasma will remain a mystery until additional observations can provide more insight.
Published Toothed whale echolocation organs evolved from jaw muscles
(via sciencedaily.com) Original source Genetic analysis finds evidence suggesting that acoustic fat bodies in the heads of toothed whales were once the muscles and bone marrow of the jaw.
Published Bringing multidrug-resistant pathogens to their knees
(via sciencedaily.com) Original source Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. A research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.
Published How the moon turned itself inside out
(via sciencedaily.com) Original source Linking analyses of the moon's gravity field with models of its earliest evolution, scientists tell a story of the moon turning itself inside out after it solidified from a primordial magma ocean. The process left behind a vestige of dense, titanium-rich material beneath its Earth-facing side that makes its presence known by gravity anomalies.
Published Mediterranean marine worm has developed enormous eyes
(via sciencedaily.com) Original source Scientists are amazed at the discovery of a bristle worm with such sharp-seeing eyes that they can measure up to those of mammals and octopuses. The researchers suspect that these marine worms may have a secretive language, which uses UV light only seen by their own species. The advanced vision of such a primitive creature helps to finally settle an epic debate about the evolution of eyes.
Published Telescope detects unprecedented behavior from nearby magnetar
(via sciencedaily.com) Original source Captured by cutting-edge radio telescope technology, a chance reactivation of a magnetar -- the Universe's most powerful magnets -- has revealed an unexpectedly complex environment.
Published Can language models read the genome? This one decoded mRNA to make better vaccines
(via sciencedaily.com) Original source Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular biology.
Published Astronomy: How do brown dwarfs form?
(via sciencedaily.com) Original source New observations provide insights into whether the birth of the giant planets takes a similar course to that of stars.
Published CHEOPS detects a 'rainbow' on an exoplanet
(via sciencedaily.com) Original source The CHEOPS space telescope is providing new information on the mysterious exoplanet WASP-76b. This ultra-hot giant is characterized by an asymmetry between the amount of light observed on its eastern terminator -- the fictitious line that separates its night side from its day side -- and that observed on its western terminator. This peculiarity is thought to be due to a 'glory', a luminous phenomenon similar to a rainbow, which occurs if the light from the star -- the 'sun' around which the exoplanet orbits -- is reflected by clouds made up of a perfectly uniform substance. If this hypothesis is confirmed, this would be the first detection of this phenomenon outside our solar system.
Published Stellar collisions produce strange, zombie-like survivors
(via sciencedaily.com) Original source Densely packed, fast-moving stars at the Milky Way's center can collide with each other. New research uses simulations to explore the outcomes of these collisions. Some collisions are more like 'violent high fives' while others are full-on mergers.
Published Finds at Schöningen show wood was crucial raw material 300,000 years ago
(via sciencedaily.com) Original source During archaeological excavations in the Schoningen open-cast coal mine in 1994, the discovery of the oldest, remarkably well-preserved hunting weapons known to humanity caused an international sensation. Spears and a double-pointed throwing stick were found lying between animal bones about ten meters below the surface in deposits at a former lakeshore. In the years that followed, extensive excavations have gradually yielded numerous wooden objects from a layer dating from the end of a warm interglacial period 300,000 years ago. The findings suggested a hunting ground on the lakeshore.
Published Researchers envision sci-fi worlds involving changes to atmospheric water cycle
(via sciencedaily.com) Original source Human activity is changing the way water flows between the Earth and atmosphere in complex ways and with likely long-lasting consequences that are hard to picture. Researchers enlisted water scientists from around the globe to write story-based scenarios about the possible futures humanity is facing but perhaps can't quite comprehend yet. The results are part of a creative pathway to understand atmospheric water research with an eye towards the potential economic and policy issues that may be just beyond the horizon.