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Categories: Biology: Molecular, Offbeat: General
Published Fossil spines reveal deep sea's past
(via sciencedaily.com) Original source Right at the bottom of the deep sea, the first very simple forms of life on earth probably emerged a long time ago. Today, the deep sea is known for its bizarre fauna. Intensive research is being conducted into how the number of species living on the sea floor have changed in the meantime. Some theories say that the ecosystems of the deep sea have emerged again and again after multiple mass extinctions and oceanic upheavals. Today's life in the deep sea would thus be comparatively young in the history of the Earth. But there is increasing evidence that parts of this world are much older than previously thought.
Published Human shoulders and elbows first evolved as brakes for climbing apes
(via sciencedaily.com) Original source Researchers report that the flexible shoulders and elbows that allow us to throw a football or reach a high shelf may have evolved as a natural braking system that let our primate ancestors get out of trees without dying. The researchers used sports-analysis software to compare the climbing movements of chimpanzees and small monkeys called mangabeys. While the animals climb up trees similarly, the researchers found that the shallow, rounded shoulder joints and shortened elbow bones that chimps have -- similar to humans -- allow them to fully extend their arms above their heads when climbing down, holding onto branches like a person going down a ladder to support their greater weight. When early humans left forests for the grassy savanna, these versatile appendages would have been essential for gathering food and using tools for hunting and defense. The findings are among the first to identify the significance of 'downclimbing' in the evolution of apes and early humans.
Published New ribozyme can make RNA molecules accessible for click chemistry in living cells
(via sciencedaily.com) Important progress for RNA research: A team has discovered a new ribozyme that can label RNA molecules in living cells.
Published Bird flu is undergoing changes that could increase the risk of widespread human transmission
(via sciencedaily.com) Original source A new study has shown that a subtype of avian flu virus, endemic in poultry farms in China, is undergoing mutational changes, which could increase the risk of the disease being passed on to humans.
Published Deciphering the 'highway code' of our cells
(via sciencedaily.com) Original source Cancers, degenerative diseases: deregulation of our cells' internal communication pathways is at the root of many conditions. Microtubules -- microscopic protein filaments -- play a crucial role in controlling these exchanges. However, their mechanisms remain poorly understood. A team has identified a new mechanism, involving two proteins, that governs their growth. The discovery opens up unprecedented prospects for the development of new treatments that can act at the very heart of cells.
Published Will it slip or will it grip: scientists ask, 'what is snail mucus?'
(via sciencedaily.com) Original source Scientists profile the mucus of Cornu aspersum -- a snail species used in beauty product formulation and eaten as escargot -- and detail the composition of three unique types of secretions -- one that hydrates and protects its skin, another that works as a glue-like adhesive, and another that lubricates to allow the animal to move freely across surfaces.
Published Immune cells shape their own path
(via sciencedaily.com) Original source When fighting disease, our immune cells need to reach their target quickly. Researchers have now discovered that immune cells actively generate their own guidance system to navigate through complex environments. This challenges earlier notions about these movements. The researchers' findings enhance our knowledge of the immune system and offer potential new approaches to improve human immune response.
Published Scientists unpick how lung cells induce immune response to influenza
(via sciencedaily.com) Original source Researchers have discovered some new and surprising ways that viral RNA and influenza virus are detected by human lung cells, which has potential implications for treating people affected by such viruses.
Published Webb reveals new structures within iconic supernova
(via sciencedaily.com) NASA's James Webb Space Telescope has begun the study of one of the most renowned supernovae, SN 1987A (Supernova 1987A). Located 168,000 light-years away in the Large Magellanic Cloud, SN 1987A has been a target of intense observations at wavelengths ranging from gamma rays to radio for nearly 40 years, since its discovery in February of 1987. New observations by Webb's NIRCam (Near-Infrared Camera) provide a crucial clue to our understanding of how a supernova develops over time to shape its remnant.
Published Scientists detect and validate the longest-period exoplanet found with TESS
(via sciencedaily.com) Scientists have detected and validated two of the longest-period exoplanets found by TESS to date. These long period large exoplanets orbit a K dwarf star and belong to a class of planets known as warm Jupiters, which have orbital periods of 10-200 days and are at least six times Earth's radius. This recent discovery offers exciting research opportunities for the future of finding long-period planets that resemble those in our own solar system.
Published New giant planet evidence of possible planetary collisions
(via sciencedaily.com) A Neptune-sized planet denser than steel has been discovered by an international team of astronomers, who believe its composition could be the result of a giant planetary clash.
Published Breathe! The shape-shifting ball that supports mental health
(via sciencedaily.com) A soft ball designed to support mental health by 'personifying' breath has been invented by a computer science student.
Published The scent of the afterlife unbottled in new study of ancient Egyptian mummification balms
(via sciencedaily.com) Original source A team of researchers has recreated one of the scents used in the mummification of an important Egyptian woman more than 3500 years ago.
Published How to write in water
(via sciencedaily.com) Original source Researchers have overcome a fundamental obstacles for writing and drawing lines, letters, and complex patterns within the bulk of a liquid.
Published How some ion channels form structures permitting drug delivery
(via sciencedaily.com) Original source A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a new study. The discovery is a significant advance in cell biology, likely solves a long-standing mystery about an unusual feature of some ion channels and has implications for the development of drugs targeting these proteins and for drug delivery.
Published Bacteria treatment reduces insulin resistance, protects against diabetes
(via sciencedaily.com) Original source Researchers have discovered a type of gut bacteria that might help improve insulin resistance, and thus protect against the development of obesity and type-2 diabetes. The study involved genetic and metabolic analysis of human fecal microbiomes and then corroborating experiments in obese mice.
Published Newly engineered versions of bacterial enzyme reveal how antibiotics could be more potent
(via sciencedaily.com) Original source Researchers applied a new technology to generate the full inventory of mutations in the bacterial species Escherichia coli where the antibiotic rifampicin attaches to and disables an essential bacterial enzyme known as RNA polymerase (RNAP).
Published Enhancing cancer therapy using functionalized photosynthetic bacteria
(via sciencedaily.com) Original source Selective targeting of cancerous cells poses major clinical challenges during cancer therapy. However, this limitation can be overcome by using bioengineered bacteria with highly optimized chemical modifications. A recent study demonstrates the use of chemically modified purple photosynthetic bacteria for the successful detection and elimination of colon cancer cells in a mouse model. The study also sheds light on the underlying mechanism of action.
Published New approach to fighting malaria
(via sciencedaily.com) Original source Findings can open up new avenues for targeted approaches toward therapeutic strategies against the malaria-causing P. falciparum that are aimed at stopping the parasite's life cycle progression and its sexual differentiation, thus blocking the transmission of the parasite into mosquitoes.
Published Unlocking the secrets of cell antennas
(via sciencedaily.com) Original source The NSL (non-specific lethal) complex regulates thousands of genes in fruit flies and mammals. Silencing the NSL genes leads to the death of the organism, which gave the complex its curious name. Researchers have now discovered that the genes regulated by the NSL complex also include genes of the intraciliary transport system. This enables different cell types to form cilia on their surface, which are important for cell communication. The study shows that these genes are 'switched on' by the NSL complex, regardless of whether a particular cell has cilia or not. The researchers found that this class of cilia-associated genes is crucial for the function of podocytes. This is a highly specialized cell type of the kidney that, paradoxically, does not have cilia. These findings have important implications for ciliopathies and kidney disease.