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Categories: Biology: Molecular, Offbeat: General

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A groundbreaking study is reshaping our understanding of crocodile evolution by pinpointing the onset of slow growth rates to the Late Triassic period, much earlier than the previously assumed Early Jurassic timeline. The research highlights newly discovered fossil crocodile ancestors (known as crocodylomorphs) that exhibited slow growth rates, similar to modern-day crocodilians. Intriguingly, these early crocodylomorphs were not the lethargic, semi-aquatic creatures we are familiar with today; they were small, active, and fully terrestrial. The study also suggests that this slow-growth strategy was not a mere evolutionary quirk but a survival mechanism, as only the slow-growing crocodylomorphs managed to survive the End-Triassic mass extinction. This stands in stark contrast to the fast-growing dinosaurs of the same era, setting the stage for the divergent evolutionary paths that would later define their modern descendants.

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A research team has uncovered a treasure trove of uncharacterized proteins. Embracing the recent deep learning revolution, they discovered hundreds of new protein families and even a novel predicted protein fold.

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Marine virologists analyzed sediment from the Mariana Trench, the deepest place on Earth, and identified a new bacteriophage.

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Scientists have synthesized spider silk from genetically modified silkworms, producing fibers six times tougher than the Kevlar used in bulletproof vests. The study is the first to successfully produce full-length spider silk proteins using silkworms. The findings demonstrate a technique that could be used to manufacture an environmentally friendly alternative to synthetic commercial fibers such as nylon.

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X-rays of an ancient jawless fish shows earliest-known example of internal cartilage skull, unlike that of any other known vertebrate.

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A new study finds that most Rafflesia species, which produce the world's largest flowers, face extinction. Lack of protection at local, national, and international levels means that remaining populations are under critical threat.

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A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational changes, that help to explain the enzyme's biochemistry. This work might help researchers engineer enzymes that facilitate unusual chemistry or are highly efficient at room temperature that are useful in chemical industry.

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Life on a faraway planet -- if it's out there -- might not look anything like life on Earth. But there are only so many chemical ingredients in the universe's pantry, and only so many ways to mix them. Scientists have now exploited those limitations to write a cookbook of hundreds of chemical recipes with the potential to give rise to life. Their ingredient list could focus the search for life elsewhere in the universe by pointing out the most likely conditions -- planetary versions of mixing techniques, oven temperatures and baking times -- for the recipes to come together.

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Researchers have discovered 16 new species of strange-looking parasitoid wasps from the Loboscelidia group. The study also revealed for the first time the unique parasitic behavior of a captive female from one species, who after parasitizing her host egg, buried the egg in a hole in the soil.

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Researchers combined soft microactuators with high-energy-density chemical fuel to create an insect-scale quadrupedal robot that is powered by combustion and can outrace, outlift, outflex and outleap its electric-driven competitors.

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A new study sheds new light on the origins of modern brain cells. Researchers find evidence that specialized secretory cells found in placozoans, tiny sea creatures the size of a grain of sand, have many similarities to the neuron, such as the genes required to create a partial synapse. From an evolutionary point of view, early neurons might have started as something like these cells, eventually gaining the ability to create a complete synapse, form axons and dendrites and create ion channels that generate fast electrical signals -- innovations which gave rise to the neuron in more complex animals such as jellyfish. Though the complete story of how the first neuron appeared remains to be told, the study demonstrates that the basic building blocks for our brain cells were forming in the ancestors of placozoans grazing inconspicuously in the shallow seas of Earth around 800 million years ago.

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A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This resulted in the reconstruction of skin and skeletal muscle transcriptomes from an extinct species for the first time. The researchers note that their findings have relevant implications for international efforts to resurrect extinct species, including both the Tasmanian tiger and the woolly mammoth, as well as for studying pandemic RNA viruses.

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Scientists are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants. In a new study, they present two enzymes from the CYP87A family as key enzymes that catalyze the formation of pregnenolone, the precursor for the biosynthesis of plant steroids, in two different plant families. The discovery of such enzymes should help to develop platforms for the cheap and sustainable production of high quality steroid compounds for medical use.

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New research is challenging the scientific status quo on the limits of the nuclear chart in hot stellar environments where temperatures reach billions of degrees Celsius.

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Microbiologists have discovered a new intestinal microbe that feeds exclusively on taurine and produces the foul-smelling gas hydrogen sulfide. The researchers have thus provided another building block in the understanding of those microbial processes that have fascinating effects on health. This is also true of Taurinivorans muris: the bacterium shows a protective function against Klebsiella and Salmonella, two important pathogens.

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It takes over the brains of ants, causing them to cling to blades of grass against their will. The lancet liver fluke has an exceptional lifecycle strategy, in which snails, ants and grazing animals are unwitting actors. Researchers now reveal more about the mind-bending workings of this tiny parasite.

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The feel of a cat's fur can reveal some information, but seeing the feline provides critical details: is it a housecat or a lion? While the sound of fire crackling may be ambiguous, its scent confirms the burning wood. Our senses synergize to give a comprehensive understanding, particularly when individual signals are subtle. The collective sum of biological inputs can be greater than their individual contributions. Robots tend to follow more straightforward addition, but researchers have now harnessed the biological concept for application in artificial intelligence (AI) to develop the first artificial, multisensory integrated neuron.

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Researchers have developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded 'nicks' in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.

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Up to an hour after their hearts had stopped, some patients revived by cardiopulmonary resuscitation (CPR) had clear memories afterward of experiencing death and had brain patterns while unconscious linked to thought and memory, report investigators.

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Herbig-Haro (HH) objects are luminous regions surrounding newborn stars, formed when stellar winds or jets of gas spewing from these newborn stars form shock waves colliding with nearby gas and dust at high speeds. This image of HH 211 from NASA's James Webb Space Telescope reveals an outflow from a Class 0 protostar, an infantile analog of our Sun when it was no more than a few tens of thousands of years old and with a mass only 8% of the present-day Sun (it will eventually grow into a star like the Sun).