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Categories: Biology: Biotechnology, Biology: Evolutionary
Published AI opens door to safe, effective new antibiotics to combat resistant bacteria
(via sciencedaily.com) Original source In a hopeful sign for demand for more safe, effective antibiotics for humans, researchers have leveraged artificial intelligence to develop a new drug that already is showing promise in animal trials.
Published New principle for treating tuberculosis
(via sciencedaily.com) Original source Researchers have succeeded in identifying and synthesizing a group of molecules that can act against the cause of tuberculosis in a new way. They describe that the so-called callyaerins act against the infectious disease by employing a fundamentally different mechanism compared to antibiotic agents used to date.
Published Unraveling a key junction underlying muscle contraction
(via sciencedaily.com) Original source Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal kingdom and setting the stage for possible future treatments for muscular disorders.
Published Scientists discover entirely new wood type that could be highly efficient at carbon storage
(via sciencedaily.com) Original source Researchers undertaking an evolutionary survey of the microscopic structure of wood from some of the world's most iconic trees and shrubs have discovered an entirely new type of wood.
Published Injury dressings in first-aid kits provide a new technique to reveal shark species after bite incidents
(via sciencedaily.com) Original source Scientists have revealed that injury dressings found in first-aid kits can reliably be used to identify shark species involved in bite incidents by deploying medical gauze to gather DNA samples from aquatic equipment, such as surfboards.
Published Precise genetics: New CRISPR method enables efficient DNA modification
(via sciencedaily.com) Original source A research group has developed a new method that further improves the existing CRISPR/Cas technologies: it allows a more precise and seamless introduction of tags into proteins at the gene level. This technology could significantly improve research on proteins in living organisms and opens up new possibilities for medical research.
Published What shapes a virus's pandemic potential? SARS-CoV-2 relatives yield clues
(via sciencedaily.com) Original source Two of the closest known relatives to SARS-CoV-2 -- a pair of bat coronaviruses discovered by researchers in Laos -- may transmit poorly in people despite being genetically similar to the COVID-19-causing virus, a new study reveals. The findings provide clues as to why some viruses have greater 'pandemic potential' than others and how researchers might go about identifying those that do before they become widespread.
Published Organic nanozymes have broad applications from food and agriculture to biomedicine
(via sciencedaily.com) Original source Nanozymes are tiny, engineered substances that mimic the catalytic properties of natural enzymes, and they serve a variety of purposes in biomedicine, chemical engineering, and environmental applications. They are typically made from inorganic materials, including metal-based elements, which makes them unsuitable for many purposes due to their toxicity and high production costs. Organic-based nanozymes partially overcome some of these problems and have the potential for a broader range of applications, including food and agriculture, but they are still in the early stages of development. A new paper provides an overview of the current state of organic nanozymes and their future potential.
Published Platypus and chicken reveal how chromosomes balance between the sexes
(via sciencedaily.com) Original source Geneticists uncover new insights into how sex chromosome systems work in the platypus and the chicken -- which will lead to better understandings of our own sex chromosome evolution and gene regulation.
Published How researchers turn bacteria into cellulose-producing mini-factories
(via sciencedaily.com) Original source Researchers have modified certain bacteria with UV light so that they produce more cellulose. The basis for this is a new approach with which the researchers generate thousands of bacterial variants and select those that have developed into the most productive.
Published From genes to jeans: New genetic insights may lead to drought resilient cotton
(via sciencedaily.com) Original source Cotton is woven into the very fabric of our lives, from soft T-shirts to comfortable jeans and cozy bedsheets. It's the world's leading renewable textile fiber and the backbone of a global industry worth billions. As climate change intensifies, cotton farmers face increasing challenges from drought and heat. However, new research offers hope for developing more resilient varieties that can maintain high yields even under water-stressed conditions.
Published New progress in research into malignant catarrhal fever in cattle
(via sciencedaily.com) Original source A research team has published a groundbreaking study on malignant catarrhal fever (MCF). This disease is caused by the alcelaphine gammaherpesvirus 1 (AlHV-1), which infects its natural host, the wildebeest. This study sheds light on the mechanisms by which this virus, which is asymptomatic and latent in the wildebeest, causes an oligoclonal expansion of CD8+ T lymphocytes in cattle, leading to the development of MCF.
Published Scientists untangle interactions between the Earth's early life forms and the environment over 500 million years
(via sciencedaily.com) Original source The atmosphere, the ocean and life on Earth interacted over the past 500-plus million years in ways that improved conditions for early organisms to thrive. Now, an interdisciplinary team of scientists has produced a perspective article of this co-evolutionary history.
Published Researchers decipher new molecular mechanisms related to biological tissue regeneration
(via sciencedaily.com) Original source A study opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor- (TNF- ) and its receptors TNFR, molecules of key interest in biomedicine due to their involvement in multiple diseases such as obesity related to type 2 diabetes mellitus, inflammatory bowel disease and several types of cancer.
Published The ancestor of all modern birds probably had iridescent feathers
(via sciencedaily.com) Original source Birds tend to be more colorful in the tropics, and scientists wanted to find out how they got there: if colorful feathers evolved in the tropics, or if tropical birds have brightly-colored ancestors that came to the region from somwhere else. Scientists built a database of 9,409 birds to explore the spread of color across the globe. They found that iridescent, colorful feathers originated 415 times across the bird tree of life, and in most cases, arose outside of the tropics -- and that the ancestor of all modern birds likely had iridescent feathers, too.
Published Lampreys possess a 'jaw-dropping' evolutionary origin
(via sciencedaily.com) Original source Lampreys are one of only two living jawless vertebrates Jaws are formed by a key stem cell population called the neural crest New research reveals the gene regulatory changes that may explain morphological differences between jawed and jawless vertebrates.
Published Ancient marine animal had inventive past despite being represented by few species
(via sciencedaily.com) Original source Brachiopods were evolving in new directions but this did not turn into evolutionary success in terms of the numbers of species, researchers have found.
Published Size doesn't matter for mammals with more complex brains
(via sciencedaily.com) Original source Mammals that have evolved more developed brains tend to have a smaller size difference between males and females of that species, according to new research.
Published Scientists identify key protein behind spread of shingles virus
(via sciencedaily.com) Original source Scientists have discovered a new evasion strategy used by the varicella zoster virus, which causes chickenpox and shingles, that may allow it to affect tissues far from the original site of infection.
Published Researchers are closing in on a mouse model for late-onset Alzheimer's
(via sciencedaily.com) Original source Researchers are working to create the first strain of mice that's genetically susceptible to late-onset Alzheimer's, with potentially transformative implications for dementia research.