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Categories: Biology: Biotechnology, Biology: Evolutionary
Published As we age, our cells are less likely to express longer genes
(via sciencedaily.com) Original source Aging may be less about specific 'aging genes' and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers. A decline in the expression of long genes with age has been observed in a wide range of animals, from worms to humans, in various human cell and tissue types, and also in individuals with neurodegenerative disease. Mouse experiments show that the phenomenon can be mitigated via known anti-aging factors, including dietary restriction.
Published Maize genes control little helpers in the soil
(via sciencedaily.com) Original source Tiny organisms such as bacteria and fungi help to promote the health and function of plant roots. It is commonly assumed that the composition of these microbes is dependent on the properties of the soil. However, researchers have now discovered when studying different local varieties of maize that the genetic makeup of the plants also helps to influence which microorganisms cluster around the roots.
Published Decoding the plant world's complex biochemical communication networks
(via sciencedaily.com) Original source A research team has begun translating the complex molecular language of petunias. Their grammar and vocabulary are well hidden, however, within the countless proteins and other compounds that fill floral cells. Being rooted to the ground, plants can't run away from insects, pathogens or other threats to their survival. But plant scientists have long known that they do send warnings to each other via scent chemicals called volatile organic compounds.
Published How butterflies choose mates: Gene controls preferences
(via sciencedaily.com) Original source Tropical Heliconius butterflies are well known for the bright colour patterns on their wings. These striking colour patterns not only scare off predators -- the butterflies are poisonous and are distasteful to birds -- but are also important signals during mate selection. Evolutionary biologists have now exploited the diversity of warning patterns of various Heliconius species to investigate the genetic foundations of these preferences. In the process, the scientists identified a gene that is directly linked to evolutionary changes in a visually guided behavior.
Published Craving snacks after a meal? It might be food-seeking neurons, not an overactive appetite
(via sciencedaily.com) Original source Psychologists have discovered a circuit in the brain of mice that makes them crave food and seek it out, even when they are not hungry. When stimulated, this cluster of cells propels mice to forage vigorously and to prefer fatty and pleasurable foods like chocolate over healthier foods like carrots.
Published Decoding the Easter Bunny -- an eastern Finnish brown hare to represent the standard for the species' genome
(via sciencedaily.com) Original source Biologists have published a chromosomally assembled reference genome for the European brown hare. The genome consists of 2.9 billion base pairs, which form 23 autosomal chromosomes, and X and Y sex chromosomes. The timing of the genome release is very appropriate as the brown hare also represents the original Easter Bunny familiar from European folklore.
Published Across oceans and millennia: decoding the origin and history of the bottle gourd
(via sciencedaily.com) Original source Researchers have uncovered intriguing details about the origins and spread of the bottle gourd, one of the oldest domesticated crops. Their work unveils the genetic diversification and population history of this hard-shelled plant that was used to make bottles, instruments, and containers for over 10,000 years by ancient civilizations.
Published Empty 'backpacks' activate the immune system against cancer
(via sciencedaily.com) Original source Researchers have discovered that the mere act of attaching their microparticle 'backpacks' to neutrophils is enough to activate them against cancer -- no drugs needed. In experiments, backpack-bearing neutrophils shrank tumors and extended the survival of mice with cancer, and treated animals retained an immune memory of the disease. This approach opens the door to a new class of drug-free immunotherapy for cancer.
Published A protein found in human sweat may protect against Lyme disease
(via sciencedaily.com) Original source Human sweat contains a protein that may protect against Lyme disease. About one-third of the population carries a genetic variant of this protein that is associated with Lyme disease in genome-wide association studies.
Published Tanks of the Triassic: New crocodile ancestor identified
(via sciencedaily.com) Original source Dinosaurs get all the glory. But aetosaurs, a heavily armored cousin of modern crocodiles, ruled the world before dinosaurs did. These tanks of the Triassic came in a variety of shapes and sizes before going extinct around 200 million years ago. Today, their fossils are found on every continent except Antarctica and Australia.
Published Genes identified that allow bacteria to thrive despite toxic heavy metal in soil
(via sciencedaily.com) Original source Some soil bacteria can acquire sets of genes that enable them to pump the heavy metal nickel out of their systems, a study has found. This enables the bacteria to not only thrive in otherwise toxic soils but help plants grow there as well. A research team pinpointed a set of genes in wild soil bacteria that allows them to do this in serpentine soils which have naturally high concentrations of toxic nickel. The genetic discovery could help inform future bioremediation efforts that seek to return plants to polluted soils.
Published Industrial societies losing healthy gut microbes
(via sciencedaily.com) Original source Our eating habits in industrialized societies are far removed from those of ancient humans. This is impacting our intestinal flora, it seems, as newly discovered cellulose degrading bacteria are being lost from the human gut microbiome, especially in industrial societies.
Published Genetic basis for the evolution of hair discovered in the clawed frog
(via sciencedaily.com) Original source The development of hair was of central importance for the evolution of mammals and thus also of humans. However, the evolutionary origin of the genetic program of hair was previously unknown. Researchers have now been able to show that important hair components and their genetic control have already evolved in amphibians. Human hair therefore shows unexpected similarities to the claws of clawed frogs.
Published Scientists discover how Diadem butterfly mimics African Queen
(via sciencedaily.com) Original source Scientists have discovered how female Diadem butterflies have evolved to look like African Queen butterflies to repel predators.
Published How cells are ahead of the curve
(via sciencedaily.com) Original source The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.
Published Engineers measure pH in cell condensates
(via sciencedaily.com) Original source In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.
Published Less social with age
(via sciencedaily.com) Original source Scientists tested several hypotheses on the drivers of social aging in free-living Assamese macaques in Thailand. The researchers collected data on the social behavior of females for eight years and found that the size of their social networks decreases with increasing age. The females continued to interact with their close social partners, but gradually withdrew from social interactions altogether. The results contribute to the understanding of the evolutionary origins of social aging.
Published DNA origami-based vaccines toward safe and highly-effective precision cancer immunotherapy
(via sciencedaily.com) Original source Researchers have created a DNA origami platform called DoriVac, whose core component is a self-assembling square block-shaped nanostructure. DoriVac vaccines enabled tumor-bearing mice to better control the growth of tumors and to survive significantly longer than control mice.
Published Protein fragments ID two new 'extremophile' microbes--and may help find alien life
(via sciencedaily.com) Original source Perfectly adapted microorganisms live in extreme environments from deep-sea trenches to mountaintops. Learning more about how these extremophiles survive in hostile conditions could inform scientists about life on Earth and potential life on other planets.
Published Breakthrough could make automated dosing systems universal
(via sciencedaily.com) Original source Automated insulin dosing systems combine low-cost blood-glucose monitors with insulin pumps that use precision dosing to continuously regulate blood-sugar and hold it steady. Synthetic biologists have found a way to piggyback on the technology and make it universally applicable for the precision dosing of virtually any drug.