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Categories: Biology: Biotechnology, Biology: Evolutionary
Published Malaria may shorten leukocyte telomeres among sub-Saharan Africans
(via sciencedaily.com) Original source The length of telomeres in white blood cells, known as leukocytes, varies significantly among sub-Saharan African populations, researchers report. Moreover, leukocyte telomere length (LTL) is negatively associated with malaria endemicity and only partly explained by genetic factors.
Published Archaea can be picky parasites
(via sciencedaily.com) Original source A parasite that not only feeds of its host, but also makes the host change its own metabolism and thus biology. Microbiologists have shown this for the very first time in a specific group of parasitic microbes, so-called DPANN archea. Their study shows that these archaea are very 'picky eaters', which might drive their hosts to change the menu.
Published Key functions of therapeutically promising jumbo viruses
(via sciencedaily.com) Original source Viruses known as 'jumbo' phages are seen as a potential tool against deadly bacterial infections. But scientists must first decipher the extraordinary makeup of these mysterious viruses. Researchers have now uncovered a key piece of jumbo phage development that helps them counter bacteria.
Published Marriage of synthetic biology and 3D printing produces programmable living materials
(via sciencedaily.com) Original source Scientists are harnessing cells to make new types of materials that can grow, repair themselves and even respond to their environment. These solid 'engineered living materials' are made by embedding cells in an inanimate matrix that's formed in a desired shape. Now, researchers have 3D printed a bioink containing plant cells that were then genetically modified, producing programmable materials. Applications could someday include biomanufacturing and sustainable construction.
Published Novel genetic plant regeneration approach without the application of phytohormones
(via sciencedaily.com) Original source Conventional plant regeneration approaches by cell culture require the external application of plant growth regulators, including hormones. However, optimizing culture conditions can be laborious. Now, researchers have developed a novel plant regeneration system that omits the need for hormone application by genetically regulating the expression of genes that control plant cell differentiation. Their work holds significant potential in the development of genetically modified plants in a simpler and cost-effective manner.
Published New and improved way to grow the cells that give rise to the kidney's filtration system
(via sciencedaily.com) Original source Scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense promise for understanding kidney development, modeling diseases, and discovering new treatments. The team improved the chemical cocktail for generating and growing NPCs in the laboratory, enabling the sustained growth of both mouse and human NPCs in a simple 2-dimensional format.
Published Researchers parse oddity of distantly related bats in Solomon Islands that appear identical
(via sciencedaily.com) Original source A study of body size in leaf-nosed bats of the Solomon Islands has revealed surprising genetic diversity among nearly indistinguishable species on different islands.
Published Discovery of mechanism plants use to change seed oil could impact industrial, food oils
(via sciencedaily.com) Original source Researchers have discovered a new mechanism of oil biosynthesis and found a way to genetically engineer a type of test plant to more efficiently produce different kinds of seed oil that it otherwise wouldn't make. While the engineering is proof-of-concept, this discovery could lead to improved production of valuable oils used in food and by a range of industries. The modified plant overcame metabolic bottlenecks and produced significant amounts of an oil similar to castor oil that it doesn't naturally produce.
Published Unlocking the genetic mysteries behind plant adaptation: New insights into the evolution of a water-saving trait in the pineapple family (bromeliaceae)
(via sciencedaily.com) Original source Researchers have achieved a breakthrough in understanding how genetic drivers influence the evolution of a specific photosynthesis mechanism in Tillandsia (air plants). This sheds light on the complex actions that cause plant adaptation and ecological diversity.
Published Research on RNA editing illuminates possible lifesaving treatments for genetic diseases
(via sciencedaily.com) Original source The research explores how CRISPR can be used to edit RNA.
Published Study details a common bacterial defense against viral infection
(via sciencedaily.com) Original source Researchers report on the molecular assembly of one of the most common anti-phage systems -- from the family of proteins called Gabija -- that is estimated to be used by at least 8.5%, and up to 18%, of all bacteria species on Earth.
Published Surprising evolutionary pattern in yeast study
(via sciencedaily.com) Original source Research study reports intriguing findings made through innovative artificial intelligence analysis about yeasts -- small fungi that are key contributors to biotechnology, food production, and human health. These findings on simple yeast organisms not only challenge widely accepted ideas about yeast evolution, but also provides access to an incredibly rich yeast analysis dataset that could have major implications for future evolutionary biology and bioinformatics research for years to come.
Published AI deciphers new gene regulatory code in plants and makes accurate predictions for newly sequenced genomes
(via sciencedaily.com) Original source Elucidating the relationship between the sequences of non-coding regulatory elements and their target genes is key to understanding gene regulation and its variation between plant species and ecotypes. Now, an international research team developed deep learning models that link gene sequence data with mRNA copy number for several plant species and predicted the regulatory effect of gene sequence variation.
Published These jacks-of-all-trades are masters, too: Yeast study helps answer age-old biology question
(via sciencedaily.com) Original source The results suggest that internal -- not external -- factors are the primary drivers of variation in the types of carbon yeasts can eat, and the researchers found no evidence that metabolic versatility, or the ability to eat different foods, comes with any trade-offs. In other words, some yeasts are jacks-of-all-trades and masters of each.
Published Curiosity promotes biodiversity
(via sciencedaily.com) Original source Cichlid fishes exhibit differing degrees of curiosity. The cause for this lies in their genes, as reported by researchers. This trait influences the cichlids' ability to adapt to new habitats.
Published With hybrid brains, these mice smell like a rat
(via sciencedaily.com) Original source Mice lacking an olfactory system have had their sense of smell restored with neurons from rats, the first time scientists have successfully integrated the sensory apparatus of one species into another.
Published Synthetic droplets cause a stir in the primordial soup
(via sciencedaily.com) Original source Our bodies are made up of trillions of different cells, each fulfilling their own unique function to keep us alive. How do cells move around inside these extremely complicated systems? How do they know where to go? And how did they get so complicated to begin with? Simple yet profound questions like these are at the heart of curiosity-driven basic research, which focuses on the fundamental principles of natural phenomena.
Published Scientists replace fishmeal in aquaculture with microbial protein derived from soybean processing wastewater
(via sciencedaily.com) Original source Scientists have successfully replaced half of the fishmeal protein in the diets of farmed Asian seabass with a 'single cell protein' cultivated from microbes in soybean processing wastewater, paving the way for more sustainable fish farming practices.
Published Advanced cell atlas opens new doors in biomedical research
(via sciencedaily.com) Original source Researchers have developed a web-based platform that offers an unprecedented view of the human body at the cellular level. The aim is to create an invaluable resource for researchers worldwide to increase knowledge about human health and disease.
Published How immune cells communicate to fight viruses
(via sciencedaily.com) Original source Chemokines are signalling proteins that orchestrate the interaction of immune cells against pathogens and tumors. To understand this complex network, various techniques have been developed to identify chemokine-producing cells. However, it has not yet been possible to determine which cells react to these chemokines. Researchers have now developed a new class of genetically modified mice that enables the simultaneous identification of chemokine producers and sensors.