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Categories: Biology: Biotechnology, Biology: Evolutionary
Published Mudskippers could be key to understanding evolution of blinking
(via sciencedaily.com) Original source Blinking is crucial for the eye. It's how animals clean their eyes, protect them, and even communicate. But how and why did blinking originate? Researchers have studied the mudskipper, an amphibious fish that spends most of its day on land, to better understand why blinking is a fundamental behavior for life on land.
Published Researchers reveal an ancient mechanism for wound repair
(via sciencedaily.com) Original source The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published New biologic effective against major infection in early tests
(via sciencedaily.com) Original source A research team has shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus -- a bacterial species widely resistant to antibiotics.
Published Algae in Swedish lakes provide insights to how complex life on Earth developed
(via sciencedaily.com) Original source By studying green algae in Swedish lakes, a research team has succeeded in identifying which environmental conditions promote multicellularity. The results give us new clues to the amazing paths of evolution.
Published Colorado's spicy ancient history of chili peppers
(via sciencedaily.com) Original source Recently identified chili pepper fossils from Boulder and Denver museums challenge millions of years of global tomato evolutionary history. Now, that's some spicy science!
Published 360-million-year-old Irish fossil provides oldest evidence of plant self-defense in wood
(via sciencedaily.com) Original source Scientists have discovered the oldest evidence of plant self-defense in wood in a 360-million-year-old fossil from south-eastern Ireland. Plants can protect their wood from infection and water loss by forming special structures called 'tyloses'. These prevent bacterial and fungal pathogens from getting into the heartwood of living trees and damaging it. However, it was not previously known how early in the evolution of plants woody species became capable of forming such defenses. Published today in Nature Plants is the oldest evidence of tylosis formation from Late Devonian (360-million-year-old) fossil wood from the Hook Head Peninsula area, Co. Wexford, Ireland.
Published Neuroptera: Greater insect diversity in the Cretaceous period
(via sciencedaily.com) Original source An LMU team has studied the biodiversity of larvae from the insect order neuroptera over the past 100 million years.
Published Newly sequenced hornet genomes could help explain invasion success
(via sciencedaily.com) Original source The genomes of two hornet species, the European hornet and the Asian hornet (or yellow-legged hornet) have been sequenced.
Published Researchers reveal a map to study novel form of cell-to-cell communication
(via sciencedaily.com) Original source An international team of researchers lays the foundation to examine how extracellular RNA and its carrier proteins found in bodily fluids function in a healthy as well as a diseased setting, potentially providing a means to accurately implement early detection and monitor disease processes.
Published Synthetic biology meets fashion in engineered silk
(via sciencedaily.com) Original source Engineers developed a method to create synthetic spider silk at high yields while retaining strength and toughness using mussel foot proteins.
Published Reinforcement learning: From board games to protein design
(via sciencedaily.com) Original source An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields.
Published Evolution of two contagious cancers affecting Tasmanian devils underlines unpredictability of disease threat
(via sciencedaily.com) Original source Evolution of two contagious cancers affecting Tasmanian devils underlines unpredictability of disease threat. Scientists have traced the family trees of two transmissible cancers that affect Tasmanian devils and have pinpointed mutations which may drive growth of deadly diseases.
Published Fungal genetics could help develop novel biotechnologies
(via sciencedaily.com) Original source An essential pillar of Earth's ecological system, fungi have long been used to better the lives of humans. While these organisms are still vastly understudied, a new review paper suggests that their unique genomes could be used to make progress in the biotech industry.
Published Engineering the next generation of cell and gene therapies
(via sciencedaily.com) Original source Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.
Published Simple addition to corn bran could boost grain's nutritional value 15-35%
(via sciencedaily.com) Original source What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south.
Published Study links 'stuck' stem cells to hair turning gray
(via sciencedaily.com) Original source Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.
Published Loops, flags and tension in DNA
(via sciencedaily.com) Original source Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.
Published New mechanism for DNA folding
(via sciencedaily.com) Original source A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.
Published Novel nanocages for delivery of small interfering RNAs
(via sciencedaily.com) Original source Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation between the Universities of Amsterdam and Leiden, researchers have developed dedicated molecular nanocages for siRNA delivery. In a paper just out in the Journal Chem they present nanocages that are easy to prepare and display tuneable siRNA delivery characteristics.
Published Fluorescent blue coumarins in a folk-medicine plant could help us see inside cells
(via sciencedaily.com) Original source Plants that glow under ultraviolet (UV) light aren't only a figment of science fiction TV and movies. Roots of a traditional medicine plant called the orange climber, or Toddalia asiatica, can fluoresce an ethereal blue hue. And now, researchers have identified two coumarin molecules that could be responsible. These natural coumarins have unique fluorescent properties, and one of the compounds could someday be used for medical imaging.