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Categories: Biology: Biotechnology, Biology: Evolutionary

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Could the next weapon against malaria come from a better understanding of biological clocks? A new study shows that malaria parasites sync their gene activity with the circadian rhythms of their host, like two pendulum clocks with synchronized swings. If scientists can identify the molecular signals behind this mysterious synchronicity, they might be able to develop new anti-malarial drugs that throw malaria's internal clock out of step with its host, essentially 'jet-lagging' the parasites.

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A study of the relationship between the growth rate of tropical trees and the frequency of genetic mutations they accumulate suggests that older, long-lived trees play a greater role in generating and maintaining genetic diversity than short-lived trees.

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Research shows that the natural peptide, called drosocin, protects fruit flies from bacterial infections by binding to ribosomes in bacteria. Once bound, drosocin prevents the ribosome from making new proteins.

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Genes that make bacteria resistant to antibiotics are much more widespread in our environment than was previously realized. A new study shows that bacteria in almost all environments carry resistance genes, with a risk of them spreading and aggravating the problem of bacterial infections that are untreatable with antibiotics.

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Researchers show that an evolutionary change in the length of lizards' legs can have a significant impact on vegetation growth and spider populations on small islands in the Bahamas. This is one of the first times, the researchers say, that such dramatic evolution-to-environment effects have been documented in a natural setting.

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Researchers from 24 countries have analyzed the genomes of 809 individuals from 233 primate species, generating the most complete catalog of genomic information about our closest relatives to date. The project provides new insights into the evolution of primates, including humans, and their diversity. In baboons, for example, hybridization and gene flow between different species occurred in the past and is still ongoing in several regions of their range. This makes baboons a good model for the evolution of early human lineages within and outside Africa. In addition, using a specially designed AI algorithm, the genomic data enable new insights into the genetic causes of human diseases.

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The symbiotic organisms that live in corals and provide them with their dramatic colors contain fragments of ancient RNA viruses that are as much as 160 million years old.

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The seafloor is home to around one-third of all the microorganisms on the Earth and is inhabited even at a depth of several kilometers. Only when it becomes too hot does the abundance of microorganisms appear to decline. But how, and from what, do microorganisms in the deep seafloor live? How do their metabolic cycles work and how do the individual members of these buried communities interact? Researchers have now been able to demonstrate in laboratory cultures how small, liquid components of crude oil are broken down through a new mechanism by a group of microorganisms called archaea.

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Symbiotic and pathogenic fungi that interact with plants are distantly related and don't share many genetic similarities. Comparing plant pathogenic fungi and plant symbiotic fungi, scientists at the Sainsbury Laboratory Cambridge University (SLCU) have discovered that these remote relatives are using a similar group of proteins to manipulate and live within plants.

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In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

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Researchers have developed a low-cost, RNA-based technology to detect and measure biomarkers, which can help decode the body's physiology. The presence of protein biomarkers can indicate chronic or acute conditions, from arthritis to cancer to bacterial infections, for which conventional tests can cost anywhere from $100 to upwards of $1,000. The new technology can perform the same measurement for about a dollar.

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For the first time ever, scientists have uncovered evidence that a species' long-term adaptation to living in an extremely cold climate has led to the evolution of social behaviours including extended care by mothers, increased infant survival and the ability to live in large complex multilevel societies.

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Whole-genomic sequencing has revolutionized the amount and detail of genetic diversity now available to researchers to study. While the researchers previously had looked at a few hundred mobile elements or 'jumping genes,' primarily of the Alu and L1 types, they were now able to analyze over 200,000 elements computationally, confirming and expanding on previous studies. Their findings provide more evidence of the fluidity of species and continuous spread of mobile and transposable genetic elements.

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The overfishing of codfish spanning the second half of the 20th century indicates that human action can force evolutionary changes more quickly than widely believed, according to a new study.

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According to new research, the amount of oxygen in one of 10 breaths was made possible thanks to a newly identified cellular mechanism that promotes photosynthesis in marine phytoplankton. The new study identifies how a proton pumping enzyme (known as VHA) aids in global oxygen production and carbon fixation from phytoplankton.

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Geneticists have unearthed a major event in the ancient history of sturgeons and paddlefish that has significant implications for the way we understand evolution. They have pinpointed a previously hidden 'whole genome duplication' (WGD) in the common ancestor of these species, which seemingly opened the door to genetic variations that may have conferred an advantage around the time of a major mass extinction some 200 million years ago.

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Influenza epidemics, caused by influenza A or B viruses, result in acute respiratory infection. They kill half a million people worldwide every year. These viruses can also wreak havoc on animals, as in the case of avian flu. A team has now identified how the influenza A virus manages to penetrate cells to infect them. By attaching itself to a receptor on the cell surface, it hijacks the iron transport mechanism to start its infection cycle. By blocking the receptor involved, the researchers were also able to significantly reduce its ability to invade cells. These results highlight a vulnerability that could be exploited to combat the virus.

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A new study examined how bivalves -- the group that includes clams, mussels, scallops, and oysters -- evolved among many others in the period of rapid evolution known as the Cambrian Explosion. The team found that though many other lineages burst into action and quickly evolved a wide variety of forms and functions, the bivalves lagged behind. The study has implications for how we understand evolution and the impact of extinctions.

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Scientists have spent years trying to develop an effective HIV vaccine, but none have proven successful. Based on findings from a recently published study, a research team may have put science one step closer to that goal.

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Genetic analysis shows dingo populations have significantly less dog ancestry than previously thought.