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Categories: Biology: Genetics
Published Much more than waste: Tiny vesicles exchange genetic information between cells in the sea
(via sciencedaily.com) Original source Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea.
Published Hormones have the potential to treat liver fibrosis
(via sciencedaily.com) Original source Researchers have discovered previously unknown changes in a specific type of liver cells, potentially opening avenues for a new treatment for liver fibrosis, a potentially life-threatening condition. Currently, there are no drugs available to treat liver fibrosis.
Published How bacteria recognize viral invasion and activate immune defenses
(via sciencedaily.com) Original source Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.
Published Colliding ribosomes activate RNA repair
(via sciencedaily.com) Original source Researchers discover how ribosomes contribute to the recognition and removal of RNA crosslinking damage.
Published Unexpected discovery opens bioengineering opportunities for human and plant health
(via sciencedaily.com) Original source An unexpected genetic discovery in wheat has led to opportunities for metabolic engineering of versatile compounds with potential to improve its nutritional qualities and resilience to disease.
Published Genetic discovery promises high-iron vegetables and cereals
(via sciencedaily.com) Original source A genetic breakthrough has opened new opportunities for iron-fortified vegetables and cereal crops to help address the global health issue of anemia.
Published Novel C. diff structures are required for infection, offer new therapeutic targets
(via sciencedaily.com) Original source Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles.
Published A tale of two proteins: Fundamental research could make growing better crops like clockwork
(via sciencedaily.com) Original source Rhomboid-like protein 10, or RBL10, is thought to be an enzyme that degrades other proteins in the chloroplast membrane, but its function is largely unknown. Researchers are studying how RBL10 affects photosynthetic membrane lipid metabolism, an essential process in photosynthesis.
Published Evolution of taste: Early sharks were able to perceive bitter substances
(via sciencedaily.com) Original source New genetic data show that humans and sharks share bitter taste receptors, even though their evolutionary pathways separated nearly 500 million years ago.
Published New discovery on how green algae count cell divisions illuminates key step needed for the evolution of multicellular life
(via sciencedaily.com) Original source An international research team has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division.
Published How marine bristle worms use a special protein to distinguish between sunlight and moonlight
(via sciencedaily.com) Original source A research team has presented its findings on the functioning of an atypical cryptochrome protein (Cry). These proteins are found in a variety of organisms, and they are often involved in light-controlled biological processes. The marine bristle worm Platynereis dumerilii, for example, employs a special Cry protein designated L-Cry to distinguish between sunlight and moonlight as well as between different moon phases. This is essential for the worms to synchronize their reproduction to the full moon phase via an inner monthly calendar, also called circalunar clock.
Published New drug-like molecule extends lifespan, ameliorates pathology in worms and boosts function in mammalian muscle cells
(via sciencedaily.com) Original source Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process. Researchers have identified a new drug-like molecule that keeps mitochondria healthy via mitophagy, a process that removes and recycles damaged mitochondria in multicellular organisms. The compound, dubbed MIC, is a natural compound that extended lifespan in C. elegans, ameliorated pathology in neurodegenerative disease models of C. elegans, and improved mitochondrial function in mouse muscle cells.
Published Yeast cells can produce drugs for treatment of psychotic disorders
(via sciencedaily.com) Original source An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.
Published Team creates synthetic enzymes to unravel molecular mysteries
(via sciencedaily.com) Original source A bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos. The team of researchers is using a new approach, called the Synthetic Processing (SynPro) system, in zebrafish to study how Vg1 is formed. By learning the molecular rules of signal formation in a developing animal, researchers aim to engineer mechanisms -- such as giving cells new instructions -- that could play a role in treating or preventing disease.
Published Scientists use quantum biology, AI to sharpen genome editing tool
(via sciencedaily.com) Original source Scientists used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.
Published First live birth of a chimeric monkey using embryonic stem cell lines
(via sciencedaily.com) Original source A team of researchers has reported for the first time the live birth of a monkey that contains a high proportion of cells derived from a monkey stem cell line. This 'chimeric' monkey is composed of cells that originate from two genetically distinct embryos of the same species of monkey. This has previously been demonstrated in rats and mice but, until now, has not been possible in other species, including non-human primates.
Published Zen and the art of mitochondrial maintenance: The machinery of death makes a healthier life
(via sciencedaily.com) Original source While we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or 'healthspan,' that precedes the inevitable decline of advancing age. Researchers have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life by revitalizing the specialized cellular compartments called mitochondria.
Published Temperature increase triggers viral infection
(via sciencedaily.com) Original source Researchers have mapped on an atomic level what happens in a virus particle when the temperature is raised.
Published Identifying a silicon transporter to improve the yield of rice
(via sciencedaily.com) Original source Researchers identify a membrane transporter in rice that regulates the accumulation and localization of silicon in the leaves.
Published Yeast with an over half synthetic genome is created in the lab
(via sciencedaily.com) Original source Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates similarly to wild yeast strains. A global consortium is working to develop the first synthetic eukaryote genome from scratch. The team has now synthesized and debugged all sixteen yeast chromosomes.