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Categories: Biology: Genetics, Geoscience: Earth Science
Published One famous dog and a powerful new approach for understanding biology and evolutionary history
(via sciencedaily.com) Original source Ever since scientists first read the complete genetic codes of creatures like fruit flies and humans more than two decades ago, the field of genomics has promised major leaps forward in understanding basic questions in biology. Two recent articles break new ground by showing how much valuable information can be found in genomes of a single species, such as endangered orcas, or even in the DNA of an individual. That individual is a sled dog named Balto, who has been immortalized in movies and a statue for helping to bring lifesaving diphtheria antitoxin to Nome, Alaska in an epic journey across the Alaskan wilderness in the winter of 1925. With just a snippet of the dog's preserved skin researchers have made great discoveries.
Published Pulling the plug on viral infections: CRISPR isn't just about cutting
(via sciencedaily.com) Original source CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses. A new study reveals a previously unrecognized player in one such system -- a membrane protein that enhances anti-viral defense. According to study authors, the finding upends the idea that CRISPR systems mount their defense only by degrading RNA and DNA in cells.
Published Information 'deleted' from the human genome may be what made us human
(via sciencedaily.com) Original source What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.
Published Mammalian evolution provides hints for understanding the origins of human disease
(via sciencedaily.com) Original source Even though it is important to know where these variations are located in the genome, it's also useful to know how or why these genetic variations happened in the first place.
Published How dormant bacteria come back to life
(via sciencedaily.com) Original source Bacterial spores can survive for years, even centuries, without nutrients, resisting heat, UV radiation, and antibiotics. How inert, sleeping bacteria -- or spores -- spring back to life has been a century-long mystery. New research identifies how sensor proteins revive dormant bacteria. Discovery opens new routes to combat spore resistance to antibiotics and sterilization. Findings can inform novel strategies to prevent infections, food spoilage.
Published Is the ocean a solution for ushering in the era of environmentally friendly energy?
(via sciencedaily.com) Original source Researchers confirm the superiority of seawater batteries that use chelating agents.
Published Twilight zone at risk from climate change
(via sciencedaily.com) Original source Life in the ocean's 'twilight zone' could decline dramatically due to climate change, new research suggests.
Published New findings indicate gene-edited rice might survive in Martian soil
(via sciencedaily.com) Original source New research suggests future Martian botanists may be able to grow gene-edited rice on Mars.
Published Near-universal T cell immunity towards a broad range of bacteria
(via sciencedaily.com) Original source Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide manner.
Published Ocean ecosystem: Mixotrophic microorganisms play key role
(via sciencedaily.com) Original source Researchers have identified a previously unknown group of bacteria, called UBA868, as key players in the energy cycle of the deep ocean. They are significantly involved in the biogeochemical cycle in the marine layer between 200 and 1000 meters.
Published Luring the virus into a trap
(via sciencedaily.com) Original source Viruses like influenza A and Ebola invade human cells in a number of steps. Research teams investigated the final stages of viral penetration using electron tomography and computer simulations. So-called fusion pores, through which the viral genome is released into the host cell, play a central role in these processes. If they can be prevented from forming, the virus is also blocked. The Heidelberg scientists describe previously unknown mechanisms, which might lead to new approaches to prevent infections.
Published Researchers reveal an ancient mechanism for wound repair
(via sciencedaily.com) Original source The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published Massive iceberg discharges during the last ice age had no impact on nearby Greenland, raising new questions about climate dynamics
(via sciencedaily.com) Original source New findings suggest that Heinrich Events had no discernible impact on temperatures in Greenland, which could have repercussions for scientists' understanding of past climate dynamics.
Published A more precise model of the Earth's ionosphere
(via sciencedaily.com) Original source The ionosphere -- the region of geospace spanning from 60 to 1000 kilometers above the Earth -- impairs the propagation of radio signals from global navigation satellite systems (GNSS) with its electrically charged particles. This is a problem for the ever higher precision required by these systems -- both in research and for applications such as autonomous driving or precise orbit determination of satellites. Models of the ionosphere and its uneven, dynamic charge distribution can help correct the signals for ionospheric delays, which are one of the main error sources in GNSS applications. Researchers have presented a new model of the ionosphere, developed on the basis of neural networks and satellite measurement data from 19 years. In particular, it can reconstruct the topside ionosphere, the upper, electron-rich part of the ionosphere much more precisely than before. It is thus also an important basis for progress in ionospheric research, with applications in studies on the propagation of electromagnetic waves or for the analysis of certain space weather events, for example.
Published Algae in Swedish lakes provide insights to how complex life on Earth developed
(via sciencedaily.com) Original source By studying green algae in Swedish lakes, a research team has succeeded in identifying which environmental conditions promote multicellularity. The results give us new clues to the amazing paths of evolution.
Published Arctic ice algae heavily contaminated with microplastics
(via sciencedaily.com) Original source The alga Melosira arctica, which grows under Arctic sea ice, contains ten times as many microplastic particles as the surrounding seawater. This concentration at the base of the food web poses a threat to creatures that feed on the algae at the sea surface. Clumps of dead algae also transport the plastic with its pollutants particularly quickly into the deep sea -- and can thus explain the high microplastic concentrations in the sediment there.
Published Ridgecrest faults increasingly sensitive to solid Earth tides before earthquakes
(via sciencedaily.com) Original source Faults in the Ridgecrest, California area were very sensitive to solid earth tidal stresses in the year and a half before the July 2019 Ridgecrest earthquake sequence.
Published Researchers reveal a map to study novel form of cell-to-cell communication
(via sciencedaily.com) Original source An international team of researchers lays the foundation to examine how extracellular RNA and its carrier proteins found in bodily fluids function in a healthy as well as a diseased setting, potentially providing a means to accurately implement early detection and monitor disease processes.
Published Reinforcement learning: From board games to protein design
(via sciencedaily.com) Original source An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields.
Published Evolution of two contagious cancers affecting Tasmanian devils underlines unpredictability of disease threat
(via sciencedaily.com) Original source Evolution of two contagious cancers affecting Tasmanian devils underlines unpredictability of disease threat. Scientists have traced the family trees of two transmissible cancers that affect Tasmanian devils and have pinpointed mutations which may drive growth of deadly diseases.