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Categories: Biology: Genetics, Environmental: Biodiversity

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A group of natural history museums has mapped the total collections from 73 of the world's largest natural history museums in 28 countries. This is the first step of an ambitious effort to inventory global holdings that can help scientists and decision makers find solutions to urgent, wide-ranging issues such as climate change, food insecurity, human health, pandemic preparedness, and wildlife conservation.

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The medicinal secrets of the Chilean soapbark tree have been laid bare, unlocking a future of more potent, affordable, and sustainably sought vaccines. Researchers have taken a major step forward in addressing this problem, by using a combination of genome mining and bioengineering techniques to produce saponin-based vaccine adjuvants in the laboratory without harvesting material directly from trees.

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Researchers have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB. If this natural process can be harnessed with new treatments, it could present an alternative to, or improve use of antibiotics, especially where bacteria have become resistant to existing drugs.

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Damage in the human genome can be repaired. But this works better in germ cells, sperm and eggs, than in normal body cells. Responsible for this is the DREAM protein complex, which prevents the activation of all available repair mechanisms. A research team has now shown that normal body cells can also be repaired better once this complex has been deactivated. In the long run, the scientists hope to develop better therapies to prevent cancer and aging-associated diseases.

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At least 80% of sites identified as being internationally important for biodiversity on land currently contain infrastructure -- of which more than 75% contain roads. In the future, more sites that are important for biodiversity could contain powerplants, mines and oil and gas infrastructure.

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Scientists have significantly advanced the race to control plant responses to temperature on a rapidly warming planet. Key to this breakthrough is miRNA, a molecule nearly 200,000 times smaller than the width of a human hair.

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Some plants can survive months without water, only to turn green again after a brief downpour. A recent study shows that this is not due to a 'miracle gene.' Rather, this ability is a consequence of a whole network of genes, almost all of which are also present in more vulnerable varieties.

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Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. Researchers have now described a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans. These effector memory B cells appear to be poised for a rapid serum antibody response upon secondary challenge one year later.

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By combining lab experiments and mathematical modelling, researchers have found a way to predict the movement of species that could guide conservation efforts to reconnect fragmented habitats.

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Researchers find stem cells use a surprising system for discarding misfolded proteins. This unique pathway could be the key to maintaining long-term health and preventing age-related blood and immune disorders.

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When exotic species such as parrots, snakes, monkeys, or aquarium fishes are kept as pets, this may lead to unsustainable trade and impact negatively the conservation of these species globally. Understanding what drives demand among keepers may help inform adequate conservation strategies to address unsustainable trade.

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Research in languages other than English is critically important for biodiversity conservation and is shockingly under-utilized internationally, according to an international research team.

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Fewer parasites in U.S. waters might be seen by many as a good thing, but a biologist says the trend signals potential danger for fish and other wildlife.

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The small size and isolation of the endangered population of Southern Resident killer whales in the Pacific Northwest have led to high levels of inbreeding. This inbreeding has contributed to their decline, which has continued as surrounding killer whale populations expand, according to new research.

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Muscle degeneration, the most prevalent cause of frailty in hereditary diseases and aging, could be caused by a deficiency in one key enzyme in a lipid biosynthesis pathway. Researchers now characterize how the enzyme PCYT2 affects muscle health in disease and aging in laboratory mouse models.

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A global mapping project has revealed the major stressors placed upon global coastlines by human activity.

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More than 85% of the world's bird, mammal, and amphibian species live in mountains, particularly in forest habitats, but researchers report that these forests are disappearing at an accelerating rate. Globally, we have lost 78.1 million hectares (7.1%) of mountain forest since 2000 -- an area larger than the size of Texas. Much of the loss occurred in tropical biodiversity hotspots, putting increasing pressure on threatened species.

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New research has looked at the long-term environmental impact of different methods to control Japanese knotweed. Different ways of trying to control the invasive species have developed over the years but now, as sustainability becomes increasingly important, understanding the effect of these management methods is vital.This new study examines at the entire life cycle and long-term impacts of different management approaches.

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The ability of a cell to divide, to proliferate, is essential for life and gives rise to the formation of complex organisms from a single cell. It also allows the replacement of used cells from a limited number of 'stem' cells, which then proliferate and specialize. In cancer, however, cell proliferation is no longer controlled and becomes chaotic. Researchers have discovered that, in a healthy individual, certain blood immune cells, the monocytes, also have this ability to proliferate, with the aim to replace tissue macrophages, which are essential for the proper functioning of our body.

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A new discovery, reported in a global study that encompassed more than a decade of research, could lead to the breeding of corn crops that can withstand drought and low-nitrogen soil conditions and ultimately ease global food insecurity.