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Categories: Biology: General, Biology: Genetics

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A new machine-learning system can generate protein designs with certain structural features, and which do not exist in nature. These proteins could be utilized to make materials that have similar mechanical properties to existing materials, like polymers, but which would have a much smaller carbon footprint.

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Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.

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Biologists have discovered that underfed jumping spiders lose light-sensitive cells that are key to their vision.

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Drinking cranberry juice has long been a mythical prevention strategy for women who develop a urinary tract infection -- and new medical evidence shows consuming cranberry products is an effective way to prevent a UTI before it gets started. A global study looking at the benefits of cranberry products has determined cranberry juice, and its supplements, reduce the risk of repeat symptomatic UTIs in women by more than a quarter, in children by more than half, and in people susceptible to UTI following medical interventions by about 53%.

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A team of researchers has identified a single-celled organism called a ciliate as the cause of a massive die-off event to a marine animal vital to coral reef health.

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What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south.

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An interdisciplinary group of researchers is proposing a new way to think of some interactions between species, classifying a variety of plants, animals and fungi as 'nature's chefs.' Specifically, nature's chefs are organisms that provide food -- or the illusion of food -- to other organisms. The concept offers a new perspective on species interactions, which can inform how people think about food across the tree of life as well as disparate research disciplines.

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The bone density of astronauts -- of both the human and rodent variety -- decreases in space. Researchers report that changes to the gut microbiomes of space travelers might be associated with this bone loss. Rodents that spent a month or more on the International Space Station had altered and more diverse microbiomes, and the bacterial species that bloomed in space may have contributed to the increased production of molecules that are known to influence the bone remodeling process.

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Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.

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Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.

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A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.

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Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation between the Universities of Amsterdam and Leiden, researchers have developed dedicated molecular nanocages for siRNA delivery. In a paper just out in the Journal Chem they present nanocages that are easy to prepare and display tuneable siRNA delivery characteristics.

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Millipede legs grow in an unexpected way, according to new research. Previously, it was thought that when a millipede molts (sheds its exoskeleton), it grows new segments on the end of its body without legs. Then after the next molt, the previously new segments re-emerge with fully formed legs attached. However, a team has found that new segments actually contain tiny bundles of legs, which appear as transparent protrusions before molting and then become fully formed afterwards. This discovery could help us understand how not only millipedes, but also other arthropods (invertebrates with jointed legs) grow.

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Plants that glow under ultraviolet (UV) light aren't only a figment of science fiction TV and movies. Roots of a traditional medicine plant called the orange climber, or Toddalia asiatica, can fluoresce an ethereal blue hue. And now, researchers have identified two coumarin molecules that could be responsible. These natural coumarins have unique fluorescent properties, and one of the compounds could someday be used for medical imaging.

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A new global survey of 1000 forest areas shows how climate change since the peak of the last ice age has had a major impact on the diversity and distribution of tree species we see today. The results can help us predict how ecosystems will react to future changes, thus having an impact on conservation management around the globe.

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Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail. This technology has potential uses in tissue engineering, regenerative medicine, and understanding how the body works. The scientists applied their new method to control the glow of a green fluorescent protein derived from Japanese eel muscle.

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The diverse swimming techniques of the ancient reptiles that ruled the Mesozoic seas have been revealed.

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Over the past 40 years, the financial losses caused by biological invasions have been equivalent to those caused by various types of natural disasters, such as earthquakes, floods or storms; however, according to scientists, they are now increasing at a faster pace.

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Scientists have recently made a surprising discovery, with the help of a wind tunnel and a flock of birds. Songbirds, many of which make twice-yearly, non-stop flights of more than 1,000 miles to get from breeding range to wintering range, fuel themselves by burning lots of fat and a surprising amount of the protein making up lean body mass, including muscle, early in the flight. This flips the conventional wisdom on its head, which had assumed that migrating birds only ramped up protein consumption at the very end of their journeys, because they would need to use every ounce of muscle for wing-flapping, not fuel.

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The high seas have been colonized by a surprising number of coastal marine invertebrate species, which can now survive and reproduce in the open ocean, contributing strongly to the floating community composition. Researchers found coastal species, representing diverse taxonomic groups and life history traits, in the eastern North Pacific Subtropical Gyre on over 70 percent of the plastic debris they examined. Further, the debris carried more coastal species than open ocean species.