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Categories: Biology: General, Biology: Genetics
Published Pulling the plug on viral infections: CRISPR isn't just about cutting
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CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses. A new study reveals a previously unrecognized player in one such system -- a membrane protein that enhances anti-viral defense. According to study authors, the finding upends the idea that CRISPR systems mount their defense only by degrading RNA and DNA in cells.
Published Information 'deleted' from the human genome may be what made us human
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What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.
Published Mammalian evolution provides hints for understanding the origins of human disease
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Even though it is important to know where these variations are located in the genome, it's also useful to know how or why these genetic variations happened in the first place.
Published How dormant bacteria come back to life
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Bacterial spores can survive for years, even centuries, without nutrients, resisting heat, UV radiation, and antibiotics. How inert, sleeping bacteria -- or spores -- spring back to life has been a century-long mystery. New research identifies how sensor proteins revive dormant bacteria. Discovery opens new routes to combat spore resistance to antibiotics and sterilization. Findings can inform novel strategies to prevent infections, food spoilage.
Published Early-nesting ducks at increased risk due to changes in climate, land use
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Each year approximately 10 million waterfowl fly north to their breeding grounds in the Prairie Pothole Region of North America, but the landscape that greets them has changed. Weather patterns and agricultural practices have significantly transformed the pothole-dotted native grasslands that waterfowl have used for thousands of years.
Published Elephant ecosystems in decline
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Global space for Asian elephant habitats has been in rapid decline since the 1700s, a new report reveals. More than 3 million square kilometers of the Asian elephant's historic habitat range has been lost in just three centuries and may underlie present-day conflicts between elephants and people.
Published Male California sea lions are becoming bigger and better fighters as their population rebounds
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California sea lions have managed to maintain -- and, in the case of males, increase -- their average body size as their population grows and competition for food becomes fiercer. This is in contrast to other marine mammals, whose average body size tends to decrease as their numbers increase. Researchers report that sexual selection was a strong driving force for males to grow bigger and to strengthen muscles in their neck and jaw that help them fight for mates. Both male and female sea lions evaded food shortages by diversifying their diets and, in some cases, foraging further from the shore.
Published Researchers explore techniques to successfully reintroduce captive birds into the wild
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Studies show that some species may require breeding in captivity within the next 200 years to avoid extinction. This reality places heavy importance on the reintroduction practices used to successfully transfer species from captivity to the wild. A new study looks at some of the most popular conservation techniques and identifies which have the highest likelihood of success for the reintroduction of bird species back into the wild.
Published Maths unlocks molecular interactions that open window to how life evolved
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Landmark research by mathematicians sets out the definitive picture of biological adaptation at the level of intermolecular interactions.
Published New findings indicate gene-edited rice might survive in Martian soil
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New research suggests future Martian botanists may be able to grow gene-edited rice on Mars.
Published A healthy but depleted herd: Predators decrease prey disease levels but also population size
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Nature documentaries will tell you that lions, cheetahs, wolves and other top predators target the weakest or slowest animals and that this culling benefits prey herds, whether it's antelope in Africa or elk in Wyoming. This idea has been widely accepted by biologists for many years and was formalized in 2003 as the healthy herds hypothesis. It proposes that predators can help prey populations by picking off the sick and injured and leaving healthy, strong animals to reproduce.
Published Abundance of urban honeybees adversely impacts wild bee populations
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Researchers argue that the rapid growth in urban honeybee-keeping over the past decade may be negatively impacting nearby wild bee populations. Small bees with limited foraging ranges may be especially at risk, they write.
Published Brain circuits for locomotion evolved long before appendages and skeletons
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Scientists found parallels between the neural circuitry that guides locomotion in sea slugs and in more complex animals like mammals.
Published Near-universal T cell immunity towards a broad range of bacteria
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Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide manner.
Published Ocean ecosystem: Mixotrophic microorganisms play key role
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Researchers have identified a previously unknown group of bacteria, called UBA868, as key players in the energy cycle of the deep ocean. They are significantly involved in the biogeochemical cycle in the marine layer between 200 and 1000 meters.
Published Jellyfish-like robots could one day clean up the world's oceans
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Roboticists have developed a jellyfish-inspired underwater robot with which they hope one day to collect waste from the bottom of the ocean. The almost noise-free prototype can trap objects underneath its body without physical contact, thereby enabling safe interactions in delicate environments such as coral reefs. Jellyfish-Bot could become an important tool for environmental remediation.
Published Antimicrobial use in agriculture can breed bacteria resistant to first-line human defenses
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A new study has shown that overuse of antimicrobials in livestock production can drive the evolution of bacteria more resistant to the first line of the human immune response. Bacteria that had evolved resistance to colistin, an antimicrobial widely used in farming, also showed resistance to compounds that are key components of human and animal immune systems. The results indicate that farmed pigs and chickens could harbour large reservoirs of cross-resistant bacteria, capable of fuelling future epidemics.
Published Luring the virus into a trap
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Viruses like influenza A and Ebola invade human cells in a number of steps. Research teams investigated the final stages of viral penetration using electron tomography and computer simulations. So-called fusion pores, through which the viral genome is released into the host cell, play a central role in these processes. If they can be prevented from forming, the virus is also blocked. The Heidelberg scientists describe previously unknown mechanisms, which might lead to new approaches to prevent infections.
Published Searching for ancient bears in an Alaskan cave led to an important human discovery
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Genetic analysis links 3,000-year-old bone found in cave to modern Alaska Natives.
Published Mudskippers could be key to understanding evolution of blinking
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Blinking is crucial for the eye. It's how animals clean their eyes, protect them, and even communicate. But how and why did blinking originate? Researchers have studied the mudskipper, an amphibious fish that spends most of its day on land, to better understand why blinking is a fundamental behavior for life on land.