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Categories: Biology: General, Biology: Genetics
Published New RNA-seq, metabolomics protocol offers more efficient extraction that maintains data integrity
(via sciencedaily.com) Original source Scientists have developed a new extraction protocol for RNA-seq and metabolomic analysis, offering a more complete picture of cellular activity than either technique on its own. The protocol employs a streamlined extraction from a single sample, which reduces variation, improves efficiency, preserves data fidelity and maximizes use of precious biospecimens.
Published Chances of eliminating HIV infection increased by novel dual gene-editing approach
(via sciencedaily.com) Original source Gene-editing therapy aimed at two targets -- HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells -- can effectively eliminate HIV infection, new research shows. The study combines a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1.
Published Scientists present evidence for a billion-years arms race between viruses and their hosts
(via sciencedaily.com) Original source Researchers have proposed a new evolutionary model for the origin of a kingdom of viruses called Bamfordvirae, suggesting a billion-years evolutionary arms race between two groups within this kingdom and their hosts.
Published Fossil find in California shakes up the natural history of cycad plants
(via sciencedaily.com) Original source According to researchers, a new analysis of an 80-million-year-old permineralized pollen cone found in the Campanian Holz Shale formation located in Silverado Canyon, California, offers a more accurate cycad natural history -- one where the plants diversified during the Cretaceous.
Published 'Zero plant extinction' is possible, says plant ecologist
(via sciencedaily.com) Original source Like animals, many plant species are struggling to adapt to a human-dominated planet. However, plants are often overlooked in conservation efforts, even though they are cheaper and easier to protect than animals and play a pivotal role in bolstering our food, fuel, and medical systems. A plant ecologist suggests an approach for preventing all future land plant extinctions across the globe which includes training more plant experts, building an online 'metaherbarium,' and creating 'microreserves.'
Published Wiggly proteins guard the genome
(via sciencedaily.com) Original source Dynamic network in the pores of the nuclear envelope blocks dangerous invaders.
Published Do people and monkeys see colors the same way?
(via sciencedaily.com) Original source New findings in color vision research imply that humans can perceive a greater range of blue tones than monkeys do. Distinct connections found in the human retina may indicate recent evolutionary adaptations for sending enhanced color vision signals from the eye to the brain.
Published New mechanisms regulating plant response to temperature
(via sciencedaily.com) Original source Discovery of a new protein complex helps scientists understand how plants interpret changes in temperature over time
Published Herpes study adds to understanding of viral reinfections, how to potentially prevent them
(via sciencedaily.com) Original source A new study on herpes infections of the eye helps shed light on the question of viral reinfections by identifying a key protein involved in viral reinfections that could be targeted by antiviral drugs.
Published Machine learning helps scientists identify the environmental preferences of microbes
(via sciencedaily.com) Original source A machine-learning approach can give scientists insight into the environmental preferences of microbes, based only on their genes. The approach has practical research implications: it could help researchers more efficiently grow bacteria in the laboratory. It could also lead to smarter use of microbes in agriculture, ecological restoration, and even probiotics.
Published Previously unknown intercellular electricity may power biology
(via sciencedaily.com) Original source Researchers have discovered that the electrical fields and activity that exist through a cell's membrane also exist within and around another type of cellular structure called biological condensates. Like oil droplets floating in water, these structures exist because of differences in density. Their foundational discovery could change the way researchers think about biological chemistry. It could also provide a clue as to how the first life on Earth harnessed the energy needed to arise.
Published New research redefines mammalian tree of life
(via sciencedaily.com) Original source Scientists from around the globe are using the largest mammalian genomic dataset in history to determine the evolutionary history of the human genome in the context of mammalian evolutionary history. Their ultimate goal is to better identify the genetic basis for traits and diseases in people and other species.
Published Artificial photosynthesis for environmentally friendly food production
(via sciencedaily.com) Original source Ensuring the supply of food to the constantly growing world population and protecting the environment at the same time are often conflicting objectives. Now researchers have successfully developed a method for the synthetic manufacture of a nutritional protein using a type of artificial photosynthesis. The animal feed industry is the primary driver of high demand for large volumes of this nutritional protein L-alanine, which is also suitable for use in meat substitute products.
Published Are the least social animals the most innovative?
(via sciencedaily.com) Original source Innovating, i.e. the ability to find solutions to new problems or innovative solutions to known problems, it provides crucial benefits for the adaptation and the survival of human beings as well as for animals. What are the characteristics that make specific species or animals to be innovative? A study has analyzed this cognitive skill in ungulates, a group of mammals such as dromedaries, horses and goats, characterized by walking on the tip of their toes or hooves. The results show that those individuals that are less integrated in the group and those that are more afraid of new objects were the best at solving a challenge posed by the researchers: opening a food container.
Published Ecosystem evolution in Africa
(via sciencedaily.com) Original source New research pushes back the oldest evidence of C4 grass-dominated habitats in Africa -- and globally -- by more than 10 million years, with important implications for primate evolution and the origins of tropical C4 grasslands and savanna ecosystems across the African continent and around the world.
Published Scientists identify antivirals that could combat emerging infectious diseases
(via sciencedaily.com) Original source A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics.
Published The reasons why insect numbers are decreasing
(via sciencedaily.com) Original source Researchers are investigating the causes and consequences of the worldwide insect decline as well as considering potential countermeasures.
Published Scientists slow aging by engineering longevity in cells
(via sciencedaily.com) Original source Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
Published Genomes from 240 mammal species explain human disease risks
(via sciencedaily.com) Original source Why is it that certain mammals have an exceptional sense of smell, some hibernate, and yet others, including humans, are predisposed to disease? A major international research project has surveyed and analyzed the genomes of 240 different mammals. The results show how the genomes of humans and other mammals have developed over the course of evolution. The research shows which regions have important functions in mammals, which genetic changes have led to specific characteristics in different species and which mutations can cause disease.
Published One famous dog and a powerful new approach for understanding biology and evolutionary history
(via sciencedaily.com) Original source Ever since scientists first read the complete genetic codes of creatures like fruit flies and humans more than two decades ago, the field of genomics has promised major leaps forward in understanding basic questions in biology. Two recent articles break new ground by showing how much valuable information can be found in genomes of a single species, such as endangered orcas, or even in the DNA of an individual. That individual is a sled dog named Balto, who has been immortalized in movies and a statue for helping to bring lifesaving diphtheria antitoxin to Nome, Alaska in an epic journey across the Alaskan wilderness in the winter of 1925. With just a snippet of the dog's preserved skin researchers have made great discoveries.