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Categories: Biology: Genetics, Computer Science: Artificial Intelligence (AI)
Published Single-celled kamikazes spearhead bacterial infection
(via sciencedaily.com) Original source You suddenly feel sick -- pathogenic bacteria have managed to colonize and spread in your body! The weapons they use for their invasion are harmful toxins that target the host's defense mechanisms and vital cell functions. Before these deadly toxins can attack host cells, bacteria must first export them from their production site -- the cytoplasm -- using dedicated secretion systems.
Published A window into plant evolution: The unusual genetic journey of lycophytes
(via sciencedaily.com) Original source An international team of researchers has uncovered a remarkable genetic phenomenon in lycophytes, which are similar to ferns and among the oldest land plants. Their study reveals that these plants have maintained a consistent genetic structure for over 350 million years, a significant deviation from the norm in plant genetics.
Published Mini-robots modeled on insects may be smallest, lightest, fastest ever developed
(via sciencedaily.com) Original source Two insect-like robots, a mini-bug and a water strider may be the smallest, lightest and fastest fully functional micro-robots ever known to be created. Such miniature robots could someday be used for work in areas such as artificial pollination, search and rescue, environmental monitoring, micro-fabrication or robotic-assisted surgery. Reporting on their work in the proceedings of the IEEE Robotics and Automation Society's International Conference on Intelligent Robots and Systems, the mini-bug weighs in at eight milligrams while the water strider weighs 55 milligrams. Both can move at about six millimeters a second.
Published DNA construction led to unexpected discovery of important cell function
(via sciencedaily.com) Original source Researchers have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding how the Notch signalling pathway works and how it is involved in several serious diseases.
Published Study identifies new findings on implant positioning and stability during robotic-assisted knee revision surgery
(via sciencedaily.com) Original source An innovative study explores the use of robotic-assisted joint replacement in revision knee scenarios, comparing the pre- and post-revision implant positions in a series of revision total knee arthroplasties (TKA) using a state-of-the-art robotic arm system.
Published Nearly dead plants brought back to life: Keys to aging hidden in the leaves
(via sciencedaily.com) Original source Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.
Published Study throws our understanding of gene regulation for a loop
(via sciencedaily.com) Original source To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.
Published Machine learning reveals sources of heterogeneity among cells in our bodies
(via sciencedaily.com) Original source A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Glowing COVID-19 diagnostic test prototype produces results in one minute
(via sciencedaily.com) Original source Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.
Published 'Smart glove' can boost hand mobility of stroke patients
(via sciencedaily.com) Original source This month, a group of stroke survivors in British Columbia will test a new technology designed to aid their recovery, and ultimately restore use of their limbs and hands. Participants will wear a new groundbreaking 'smart glove' capable of tracking their hand and finger movements during rehabilitation exercises.
Published Bioinformatics: Researchers develop a new machine learning approach
(via sciencedaily.com) Original source To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published A novel pathway regulating lipid biosynthesis by fatty acids
(via sciencedaily.com) Original source Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published New insights into what helps Salmonella cause infections
(via sciencedaily.com) Original source In a new study, researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging
(via sciencedaily.com) Original source Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published New rice lines for Africa offer virus protection
(via sciencedaily.com) Original source The so-called Rice Yellow Mottle Virus (for short: RYMV) is responsible for high crop losses in Africa, particularly among small-scale farmers. A research team has now produced rice lines that are resistant to the disease by means of genome editing. The rice varieties are a preliminary step toward being able to generate resistant locally adapted elite varieties for small-scale food producers in Africa.
Published Spying on a shape-shifting protein
(via sciencedaily.com) Original source Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.
Published Study uncovers potential origins of life in ancient hot springs
(via sciencedaily.com) Original source A research team investigated how the emergence of the first living systems from inert geological materials happened on the Earth, more than 3.5 billion years ago. Scientists found that by mixing hydrogen, bicarbonate, and iron-rich magnetite under conditions mimicking relatively mild hydrothermal vent results in the formation of a spectrum of organic molecules, most notably including fatty acids stretching up to 18 carbon atoms in length.
Published Lab-grown retinas explain why people see colors dogs can't
(via sciencedaily.com) Original source With human retinas grown in a petri dish, researchers discovered how an offshoot of vitamin A generates the specialized cells that enable people to see millions of colors, an ability that dogs, cats, and other mammals do not possess. The findings increase understanding of color blindness, age-related vision loss, and other diseases linked to photoreceptor cells. They also demonstrate how genes instruct the human retina to make specific color-sensing cells, a process scientists thought was controlled by thyroid hormones.
Published Protein complex discovered to control DNA repair
(via sciencedaily.com) Original source The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published Artificial muscle device produces force 34 times its weight
(via sciencedaily.com) Original source Scientists developed a soft fluidic switch using an ionic polymer artificial muscle that runs with ultra-low power to lift objects 34 times greater than its weight. Its light weight and small size make it applicable to various industrial fields such as soft electronics, smart textiles, and biomedical devices by controlling fluid flow with high precision, even in narrow spaces.