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Categories: Biology: Genetics, Computer Science: Artificial Intelligence (AI)
Published Ancient microbes offer clues to how complex life evolved
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Researchers have discovered that a single-celled organism, a close relative of animals, harbors the remnants of ancient giant viruses woven into its own genetic code. This finding sheds light on how complex organisms may have acquired some of their genes and highlights the dynamic interplay between viruses and their hosts.
Published E. coli variant may cause antimicrobial resistance in dogs, humans
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Researchers studying antimicrobial-resistant E. coli -- the leading cause of human death due to antimicrobial resistance worldwide -- have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
Published Building a roadmap to bioengineer plants that produce their own nitrogen fertilizer
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Nitrogen fertilizers make it possible to feed the world's growing population, but they are also costly adn harm ecosystems. However, a few plants have evolved the ability to acquire their own nitrogen with the help of bacteria, and a new study helps explain how they did it, not once, but multiple times.
Published Big boost for new epigenetics paradigm: CoRSIVs, first discovered in humans, now found in cattle
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A study opens new possibilities to improve production efficiency in the cattle industry and potentially animal agriculture more broadly.
Published AI found to boost individual creativity -- at the expense of less varied content
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A new study finds that AI enhances creativity by boosting the novelty of story ideas as well as the 'usefulness' of stories -- their ability to engage the target audience and potential for publication. However, AI was not judged to enhance the work produced by more creative writers and the study also warns that while AI may enhance individual creativity it may also result in a loss of collective novelty, as AI-assisted stories were found to contain more similarities to each other and were less varied and diverse.
Published A better way to make RNA drugs
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RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.
Published Insight into one of life's earliest ancestors revealed in new study
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Researchers have shed light on Earth's earliest ecosystem, showing that within a few hundred million years of planetary formation, life on Earth was already flourishing.
Published How plant cold specialists can adapt to the environment
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Evolutionary biologists studied spoonworts to determine what influence genome duplication has on the adaptive potential of plants. The results show that polyploids -- species with more than two sets of chromosomes -- can have an accumulation of structural mutations with signals for a possible local adaptation, enabling them to occupy ecological niches time and time again.
Published Learning dance moves could help humanoid robots work better with humans
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Engineers have trained a humanoid robot to perform a variety of expressive movements, from simple dance routines to gestures like waving, high-fiving and hugging, all while maintaining a steady gait on diverse terrains. This work marks a step towards building robots that perform more complex and human-like motions.
Published How risk-averse are humans when interacting with robots?
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How do people like to interact with robots when navigating a crowded environment? And what algorithms should roboticists use to program robots to interact with humans? These are the questions that a team of mechanical engineers and computer scientists sought to answer in a recent study.
Published Opening the right doors: 'Jumping gene' control mechanisms revealed
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International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.
Published First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin
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An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.
Published AI Chatbots have shown they have an 'empathy gap' that children are likely to miss
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Artificial intelligence (AI) chatbots have frequently shown signs of an 'empathy gap' that puts young users at risk of distress or harm, raising the urgent need for 'child-safe AI', according to a new study. The research urges developers and policy actors to prioritize AI design that take greater account of children's needs. It provides evidence that children are particularly susceptible to treating chatbots as lifelike, quasi-human confidantes, and that their interactions with the technology can go awry when it fails to respond to their unique needs and vulnerabilities. The study links that gap in understanding to recent reports of cases in which interactions with AI led to potentially dangerous situations for young users.
Published Novel genome editing approach restores hearing in adult preclinical models with genetic deafness
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Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing approach. Since mouse and human microRNAs have identical sequences, the researchers hope this work can one day be translated into applications for humans.
Published A new twist on artificial 'muscles' for safer, softer robots
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Engineers have developed a new soft, flexible device that makes robots move by expanding and contracting -- just like a human muscle. To demonstrate their new device, called an actuator, the researchers used it to create a cylindrical, worm-like soft robot and an artificial bicep. In experiments, the cylindrical soft robot navigated the tight, hairpin curves of a narrow pipe-like environment, and the bicep was able to lift a 500-gram weight 5,000 times in a row without failing.
Published Pumpkin disease not evolving, could make a difference for management
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The pathogen that causes bacterial spot is very good at what it does. Forming small lesions on the rinds of pumpkins, melons, cucumbers, and other cucurbits, it mars the fruits' appearance and ushers in secondary pathogens that lead to rot and severe yield loss. The bacterium, Xanthomonas cucurbitae, is so successful that it has had no reason to evolve through time or space.
Published Atlas of proteins reveals inner workings of cells
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Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.
Published Not so simple: Mosses and ferns offer new hope for crop protection
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Mosses, liverworts, ferns and algae may offer an exciting new research frontier in the global challenge of protecting crops from the threat of disease.
Published Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease
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Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.
Published Big gain in battle against harmful bacteria
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An unexpected find has enabled important progress to be made in the battle against harmful bacteria.