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Categories: Biology: Genetics, Computer Science: Artificial Intelligence (AI)

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Evolution of two contagious cancers affecting Tasmanian devils underlines unpredictability of disease threat. Scientists have traced the family trees of two transmissible cancers that affect Tasmanian devils and have pinpointed mutations which may drive growth of deadly diseases.

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An essential pillar of Earth's ecological system, fungi have long been used to better the lives of humans. While these organisms are still vastly understudied, a new review paper suggests that their unique genomes could be used to make progress in the biotech industry.

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A new machine-learning system can generate protein designs with certain structural features, and which do not exist in nature. These proteins could be utilized to make materials that have similar mechanical properties to existing materials, like polymers, but which would have a much smaller carbon footprint.

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Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.

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Recently quantum computers started to work with more than just the zeros and ones we know from classical computers. Now a team demonstrates a way to efficiently create entanglement of such high-dimensional systems to enable more powerful calculations.

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What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south.

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Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.

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Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.

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A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.

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Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation between the Universities of Amsterdam and Leiden, researchers have developed dedicated molecular nanocages for siRNA delivery. In a paper just out in the Journal Chem they present nanocages that are easy to prepare and display tuneable siRNA delivery characteristics.

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Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail. This technology has potential uses in tissue engineering, regenerative medicine, and understanding how the body works. The scientists applied their new method to control the glow of a green fluorescent protein derived from Japanese eel muscle.

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Researchers have designed a system that makes an off-the-shelf quadruped robot nimble enough to walk a narrow balance beam -- a feat that is likely the first of its kind.

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The new smart sensor uses embedded information to detect motion in a single video frame.

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Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created infertility only in the males, impacting their sperm count, movement and shape.

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A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings. A study now shows how two molecular mechanisms can work together make the bacterium extra resistant.

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We typically think of robots as metal objects, filled with motors and circuits. But the field of molecular robotics is starting to change that. Like the formation of complex living organisms, molecular robots derive their form and functionality from assembled molecules stored in a single unit, i.e., a body. Yet manufacturing this body at the microscopic level is an engineering nightmare. Now, a team has created a simple workaround.

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Scientists have developed a software package to help answer key questions about genetic factors associated with shared characteristics among different species.

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Researchers describe how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body's ability to suppress it.

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Origin-of-life chemists propose that glyoxylate could have been the original source of sugars on the 'prebiotic' Earth

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Scientists are reporting a discovery about unexpected asymmetry on the hair cells of zebrafish that allow them to detect movement with greater sensitivity from the back than the front.