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Categories: Biology: Genetics, Computer Science: Artificial Intelligence (AI)
Published Artificial photosynthesis for environmentally friendly food production
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Ensuring the supply of food to the constantly growing world population and protecting the environment at the same time are often conflicting objectives. Now researchers have successfully developed a method for the synthetic manufacture of a nutritional protein using a type of artificial photosynthesis. The animal feed industry is the primary driver of high demand for large volumes of this nutritional protein L-alanine, which is also suitable for use in meat substitute products.
Published Scientists identify antivirals that could combat emerging infectious diseases
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A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics.
Published Highly dexterous robot hand can operate in the dark -- just like us
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Researchers demonstrated a highly dexterous robot hand, one that combines an advanced sense of touch with motor learning algorithms in order to achieve a high level of dexterity. In addition, the hand worked without any external cameras -- it's immune to lighting, occlusion, or similar issues. Because the hand doesn't rely on vision to manipulate objects, it can do so in difficult lighting conditions that would confuse vision-based algorithms -- it even operates in the dark.
Published Scientists slow aging by engineering longevity in cells
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Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
Published Genomes from 240 mammal species explain human disease risks
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Why is it that certain mammals have an exceptional sense of smell, some hibernate, and yet others, including humans, are predisposed to disease? A major international research project has surveyed and analyzed the genomes of 240 different mammals. The results show how the genomes of humans and other mammals have developed over the course of evolution. The research shows which regions have important functions in mammals, which genetic changes have led to specific characteristics in different species and which mutations can cause disease.
Published One famous dog and a powerful new approach for understanding biology and evolutionary history
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Ever since scientists first read the complete genetic codes of creatures like fruit flies and humans more than two decades ago, the field of genomics has promised major leaps forward in understanding basic questions in biology. Two recent articles break new ground by showing how much valuable information can be found in genomes of a single species, such as endangered orcas, or even in the DNA of an individual. That individual is a sled dog named Balto, who has been immortalized in movies and a statue for helping to bring lifesaving diphtheria antitoxin to Nome, Alaska in an epic journey across the Alaskan wilderness in the winter of 1925. With just a snippet of the dog's preserved skin researchers have made great discoveries.
Published Pulling the plug on viral infections: CRISPR isn't just about cutting
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CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses. A new study reveals a previously unrecognized player in one such system -- a membrane protein that enhances anti-viral defense. According to study authors, the finding upends the idea that CRISPR systems mount their defense only by degrading RNA and DNA in cells.
Published Information 'deleted' from the human genome may be what made us human
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What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.
Published Mammalian evolution provides hints for understanding the origins of human disease
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Even though it is important to know where these variations are located in the genome, it's also useful to know how or why these genetic variations happened in the first place.
Published How dormant bacteria come back to life
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Bacterial spores can survive for years, even centuries, without nutrients, resisting heat, UV radiation, and antibiotics. How inert, sleeping bacteria -- or spores -- spring back to life has been a century-long mystery. New research identifies how sensor proteins revive dormant bacteria. Discovery opens new routes to combat spore resistance to antibiotics and sterilization. Findings can inform novel strategies to prevent infections, food spoilage.
Published Speedy robo-gripper reflexively organizes cluttered spaces
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A new gripper robot grasps by reflex. Rather than start from scratch after a failed attempt, the bot adapts in the moment to reflexively roll, palm, or pinch an object to get a better hold.
Published New findings indicate gene-edited rice might survive in Martian soil
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New research suggests future Martian botanists may be able to grow gene-edited rice on Mars.
Published How a horse whisperer can help engineers build better robots
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New research shows us that age-old interactions between people and their horses can teach us something about building robots designed to improve our lives.
Published Near-universal T cell immunity towards a broad range of bacteria
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Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide manner.
Published Jellyfish-like robots could one day clean up the world's oceans
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Roboticists have developed a jellyfish-inspired underwater robot with which they hope one day to collect waste from the bottom of the ocean. The almost noise-free prototype can trap objects underneath its body without physical contact, thereby enabling safe interactions in delicate environments such as coral reefs. Jellyfish-Bot could become an important tool for environmental remediation.
Published Luring the virus into a trap
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Viruses like influenza A and Ebola invade human cells in a number of steps. Research teams investigated the final stages of viral penetration using electron tomography and computer simulations. So-called fusion pores, through which the viral genome is released into the host cell, play a central role in these processes. If they can be prevented from forming, the virus is also blocked. The Heidelberg scientists describe previously unknown mechanisms, which might lead to new approaches to prevent infections.
Published Researchers reveal an ancient mechanism for wound repair
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The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published Researchers reveal a map to study novel form of cell-to-cell communication
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An international team of researchers lays the foundation to examine how extracellular RNA and its carrier proteins found in bodily fluids function in a healthy as well as a diseased setting, potentially providing a means to accurately implement early detection and monitor disease processes.
Published ChatGPT is still no match for humans when it comes to accounting
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ChatGPT faced off against students on accounting assessments. Students scored an overall average of 76.7%, compared to ChatGPT's score of 47.4%. On a 11.3% of questions, ChatGPT scored higher than the student average, doing particularly well on AIS and auditing. But the AI bot did worse on tax, financial, and managerial assessments, possibly because ChatGPT struggled with the mathematical processes required for the latter type.
Published Reinforcement learning: From board games to protein design
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An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields.