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Categories: Biology: Cell Biology, Offbeat: General
Published Alzheimer's drug fermented with help from AI and bacteria moves closer to reality
(via sciencedaily.com) Original source Researchers combined artificial intelligence and chemical biosensors to ferment the precursor of an Alzheimer's drug in bacteria.
Published New bioengineered protein design shows promise in fighting COVID-19
(via sciencedaily.com) Original source A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.
Published An electricity generator inspired by the drinking bird toy powers electronics with evaporated water
(via sciencedaily.com) Original source Inspired by the classic drinking bird toy, scientists have developed an engine that efficiently converts energy from water evaporation into electricity to power small electronics. The device produces energy outputs exceeding 100 volts -- much higher than other techniques that generate electricity from water -- and can operate for several days using only 100 milliliters of water as fuel, according to a new study.
Published Sleep-wake rhythm: Fish change our understanding of sleep regulation
(via sciencedaily.com) Original source Researchers have discovered that some fish -- unlike humans -- do not need orexin to stay awake. This molecule was thought to be necessary for normal wake and sleep rhythms in vertebrates. Humans without orexin suffer from narcolepsy.
Published New discovery reveals how the egg controls sperm entry
(via sciencedaily.com) Original source After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.
Published Chimp moms play with their offspring through good times and bad
(via sciencedaily.com) Original source A recent study observing wild chimpanzees over a period of more than 10 years revealed that when food gets scarcer, the adults put play aside and focus on survival, while mother chimps continue to be their children's primary playmate -- suggesting their indispensable role to foster their young's physical and social development.
Published Even cells know the importance of recycling
(via sciencedaily.com) Original source Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.
Published New simpler and cost-effective forensics test helps identify touch DNA
(via sciencedaily.com) Original source Research has found a less expensive and easier to use test to learn more about forensic touch DNA. This research has important implications for forensic investigations and being able to identify DNA from a primary contact -- someone who may have committed the crime -- as well as secondary DNA that was inadvertently and indirectly transferred through touch.
Published Sulfur and the origin of life
(via sciencedaily.com) Original source A new study shines a spotlight on sulfur, a chemical element that, while all familiar, has proved surprisingly resistant to scientific efforts in probing its role in the origin of life.
Published What kinds of seismic signals did Swifties send at LA concert?
(via sciencedaily.com) Original source Seattle may have experienced its own Swift Quake last July, but at an August 2023 concert Taylor Swift's fans in Los Angeles gave scientists a lot of shaking to ponder. After some debate, a research team concluded that it was likely the dancing and jumping motions of the audience at SoFi Stadium -- not the musical beats or reverberations of the sound system -- that generated the concert's distinct harmonic tremors.
Published Robot ANYmal can do parkour and walk across rubble
(via sciencedaily.com) Original source The quadrupedal robot ANYmal went back to school and has learned a lot. Researchers used machine learning to teach it new skills: the robot can now climb over obstacles and successfully negotiate pitfalls.
Published Tryptophan in diet, gut bacteria protect against E. coli infection
(via sciencedaily.com) Original source Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure.
Published Study shows important role gut microbes play in airway health in persons with cystic fibrosis
(via sciencedaily.com) Original source Findings from a new study reflect the important role that the gut microbiome (communities of bacteria) plays in the airway health of persons with cystic fibrosis.
Published New AI technology enables 3D capture and editing of real-life objects
(via sciencedaily.com) Original source Imagine performing a sweep around an object with your smartphone and getting a realistic, fully editable 3D model that you can view from any angle -- this is fast becoming reality, thanks to advances in AI. Researchers have unveiled new AI technology for doing exactly this. Soon, rather than merely taking 2D photos, everyday consumers will be able to take 3D captures of real-life objects and edit their shapes and appearance as they wish, just as easily as they would with regular 2D photos today.
Published Steroid drugs used for HRT can combat E. coli and MRSA
(via sciencedaily.com) Original source Researchers have combined computational and microbiology laboratory approaches to identify existing drugs that can be repurposed to combat antibiotic-resistant bacterial infections. This research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.
Published New computational strategy boosts the ability of drug designers to target proteins inside the membrane
(via sciencedaily.com) Original source Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.
Published You don't need glue to hold these materials together -- just electricity
(via sciencedaily.com) Original source Is there a way to stick hard and soft materials together without any tape, glue or epoxy? A new study shows that applying a small voltage to certain objects forms chemical bonds that securely link the objects together. Reversing the direction of electron flow easily separates the two materials. This electro-adhesion effect could help create biohybrid robots, improve biomedical implants and enable new battery technologies.
Published Sonic youth: Healthy reef sounds increase coral settlement
(via sciencedaily.com) Original source Healthy coral reefs have rich soundscapes, full of the croaks, purrs, and grunts of various fishes and the crackling of snapping shrimp. Larval coral uses these sounds as cues to identify the best places to settle and grow. The authors found that sound could potentially be a vital tool in the effort to restore coral reefs. Broadcasting the sounds of a healthy reef to a reef that is degraded encourages coral larvae to settle there. This indicates that it's possible that 'acoustic enrichment' can be a key intervention to support imperiled reefs.
Published Simple trick could improve accuracy of plant genetics research
(via sciencedaily.com) Original source Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables -- such as temperature -- affect gene activity in plants.
Published Milk to the rescue for diabetics? Cow produces human insulin in milk
(via sciencedaily.com) Original source An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.