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Categories: Biology: Cell Biology, Geoscience: Severe Weather

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Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Ecology: Endangered Species
Published

Mitochondrial genome editing technique yields useful traits      (via sciencedaily.com)     Original source 

Tweaks to the mitochondrial genome hold the potential for better hybrid seed production or to introduce seedless fruits.

Biology: Biochemistry Biology: Cell Biology Biology: General
Published

Living in a disadvantaged neighborhood affects food choices, weight gain and the microstructure of the brain      (via sciencedaily.com)     Original source 

A new study finds poor quality of available foods, increased intake of calories from foods high in trans-fatty acids, and environments that do not foster physical activity, all prevalent in disadvantaged neighborhoods, disrupt the flexibility of information processing in the brain that is involved in reward, emotion regulation, and cognition.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Genome editing: Reducing off-target mutations in DNA      (via sciencedaily.com)     Original source 

Researchers have developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded 'nicks' in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Marine Biology: Microbiology Biology: Molecular Environmental: General Environmental: Water Geoscience: Environmental Issues Geoscience: Geochemistry
Published

Genetically modified bacteria break down plastics in saltwater      (via sciencedaily.com)     Original source 

Researchers have genetically engineered a marine microorganism to break down plastic in salt water. Specifically, the modified organism can break down polyethylene terephthalate (PET), a plastic used in everything from water bottles to clothing that is a significant contributor to microplastic pollution in oceans.

Biology: Cell Biology Biology: Developmental Biology: General
Published

Using topology, Researchers advance understanding of how cells organize themselves      (via sciencedaily.com)     Original source 

R esearchers created a machine learning algorithm using computational topology that profiles shapes and spatial patterns in embryos to study how these cells organize themselves into tissue-like architectures. In a new study, they take that system to the next level, opening a path to studying how multiple types of cells assemble themselves.

Biology: Biotechnology Biology: Cell Biology Biology: General
Published

Specialized gut immune cells pinpointed that can limit progression of inflammatory bowel disease      (via sciencedaily.com)     Original source 

Researchers have characterized a specialized type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.

Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Researchers discover tissue-specific protection against protein aggregation      (via sciencedaily.com)     Original source 

Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail. By understanding how different tissues tackle protein build up, this research could accelerate the identification of ways to protect tissues that are vulnerable to protein build up, possibly tackling both disease-associated protein aggregates and also age-dependent aggregates that accelerate the functional decline of tissues.

Biology: Cell Biology Biology: Developmental Biology: Genetics Biology: Molecular
Published

From hagfish to membrane: Modeling age-related macular degeneration      (via sciencedaily.com)     Original source 

Researchers have successfully demonstrated that hagfish slime proteins can accurately replicate membranes in the human eye. Scientists were able to properly grow retinal cells on hagfish slime proteins and prove that the protein's behavior changes as the membrane mimics stages of aging and disease.

Biology: Cell Biology Biology: Developmental Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Flu: Interferon-gamma from T follicular helper cells is required to create lung-resident memory B cells      (via sciencedaily.com)     Original source 

During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body. One path is the B cells that differentiate into lung-resident memory B cells, or lung-BRMs, that are critical for pulmonary immunity. These long-lived, non-circulating lung-BRMs migrate to the lungs from draining lymph nodes and reside there permanently as the first layer of defense that can quickly react to produce antibodies in a future infection.

Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Mysterious family of microbial proteins hijack crops' cellular plumbing      (via sciencedaily.com)     Original source 

Some crop pathogens use a clever trick to multiply and spread infection: they hijack the plant's cellular plumbing. In a new study, researchers unveil a class of bacterial proteins that fold into a straw-like shape and insert themselves into the plant cell membrane, allowing the inside of the leaf to become waterlogged. The researchers also figured out a possible way to block the water channel proteins and prevent infection.

Biology: Cell Biology Biology: Genetics Biology: Molecular
Published

A protein on cancer cells supports the immune response against tumors      (via sciencedaily.com)     Original source 

Scientists identify a new and surprising function of a membrane protein on the surface of cancer cells: It supports and stabilizes an important 'co-stimulatory' factor that enhances the activation of T cells, thus improving the immune response against the tumor.

Environmental: Water Geoscience: Environmental Issues Geoscience: Severe Weather
Published

Ohio's droughts are worse than often recognized, study finds      (via sciencedaily.com)     Original source 

A new type of analysis suggests that droughts in Ohio were more severe from 2000 to 2019 than standard measurements have suggested.

Biology: Cell Biology Chemistry: Biochemistry
Published

Majority rule in complex mixtures      (via sciencedaily.com) 

The very first life on earth is thought to have developed from 'protocells' -- liquid mixtures of many different types of molecules. Researchers have now shown that in such mixtures, small imbalances in the number of molecules of different types can have an unexpected effect. A surprising interplay with the complex pattern of interactions strongly amplifies such imbalances -- meaning that a type of molecule that is only slightly in the majority can almost entirely separate out from the others. These fundamental findings point towards a new mechanism that will apply in many complex mixtures. For instance, this would be a way for cells to control the formation of structures by fine-tuning the concentration of different molecules.

Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Genetics Biology: Microbiology Biology: Molecular
Published

'Dormant' HIV produces RNA and proteins during anti-retroviral therapy      (via sciencedaily.com)     Original source 

HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops. These reservoirs have long been thought to be dormant, but two independent groups of researchers report that a subset of these cells spontaneously produce HIV RNA and proteins that may impact patients' HIV-specific immune responses.

Biology: Cell Biology Chemistry: Biochemistry Chemistry: General Chemistry: Inorganic Chemistry
Published

Chemist uses nature as inspiration for a sustainable, affordable adhesive system      (via sciencedaily.com) 

A chemist drew inspiration from the natural world, from his experiences scuba diving to studying shellfish in his lab. He has developed a sustainable adhesive system -- an alternative to toxic, permanent, traditional adhesives.

Biology: Cell Biology Biology: Marine Ecology: Endangered Species Ecology: Extinction Ecology: General Ecology: Invasive Species Ecology: Nature Ecology: Research Ecology: Sea Life Environmental: Biodiversity Environmental: Ecosystems Environmental: Water
Published

Freshwater connectivity can transport environmental DNA through the landscape      (via sciencedaily.com) 

A new article uses environmental DNA (eDNA) metabarcoding to analyze fish and zooplankton communities. The study found that the movement of water between freshwater bodies, or freshwater connectivity, can transport eDNA. This highlights the potential of eDNA to provide a comprehensive view of freshwater biodiversity.

Environmental: Wildfires Geoscience: Earthquakes Geoscience: Severe Weather
Published

Largest historic fire death toll belongs to aftermath of 1923 Japan Earthquake      (via sciencedaily.com)     Original source 

Fires that raged in the days following the 1 September 1923 magnitude 7.9 Kant earthquake killed roughly 90% of the 105,000 people who perished in and around Tokyo, making it one of the deadliest natural disasters in history -- comparable to the number of people killed in the World War II atomic bombing of Hiroshima. The story of the conflagration, not well-known outside of Japan, holds important lessons for earthquake scientists, emergency response teams and city planners, according to a new article.

Biology: Biotechnology Biology: Cell Biology Biology: Genetics Biology: Molecular
Published

Comprehensive insulin signalling map shows interplay between genes and diet      (via sciencedaily.com)     Original source 

Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet.

Biology: Cell Biology Biology: Genetics Biology: Microbiology
Published

Researchers discover genes behind antibiotic resistance in deadly superbug infections      (via sciencedaily.com)     Original source 

Researchers have uncovered new genetic insights into Staphylococcus aureus, revealing what makes the bacterium so dangerous when it enters the blood.

Biology: Cell Biology Biology: Microbiology Engineering: Nanotechnology
Published

Ultrathin nanotech promises to help tackle antibiotic resistance      (via sciencedaily.com) 

Researchers have invented a nano-thin superbug-slaying material that could one day be integrated into wound dressings and implants to prevent or heal bacterial infections. The innovation -- which has undergone advanced pre-clinical trials -- is effective against a broad range of drug-resistant bacterial cells, including 'golden staph', which are commonly referred to as superbugs.