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Categories: Biology: Cell Biology, Geoscience: Earthquakes

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A new study explores exactly what leads to the generation of Th17 cells -- an important subtype of cells in the intestine -- and uncovers some of the underappreciated molecular players and events that lead to cell differentiation in the gut.

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With the aid of some sea slugs, chemists have discovered that one of the smallest conceivable tweaks to a biomolecule can elicit one of the grandest conceivable consequences: directing the activation of neurons. The team has shown that the orientation of a single amino acid -- in this case, one of dozens found in the neuropeptide of a sea slug -- can dictate the likelihood that the peptide activates one neuron receptor versus another. Because different types of receptors are responsible for different neuronal activities, the finding points to another means by which a brain or nervous system can regulate the labyrinthine, life-sustaining communication among its cells.

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Extremely long tail provides structural window into how bacteria-infecting viruses called phages assemble.

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The agriculture industry is under pressure to adopt sustainable and precise agricultural practices that enable more efficient use of resources due to worsening environmental conditions resulting from climate change, an ever-expanding human population, limited resources, and a shortage of arable land. As a result, developing delivery systems that efficiently distribute micronutrients, pesticides, and antibiotics in crops is crucial to ensuring high productivity and high-quality produce while minimising resource waste. However, current and standard practices for agrochemical application in plants are inefficient. These practices cause significant detrimental environmental side effects, such as water and soil contamination, biodiversity loss and degraded ecosystems; and public health concerns, such as respiratory problems, chemical exposure and food contamination.

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Researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced. The new mouse model shows milder cognitive traits compared to a previously studied Down syndrome mouse model.

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Scientists have done research that opens up a whole new world within our cells. Their study uncovers a vast network of interactions that assist cells in adjusting in real time to withstand stresses on our health.

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Meiotic recombination assures genetic variation during breeding. During meiotic prophase I, chromosomes are organized in a loop-base array by a proteinaceous structure called meiotic chromosome axis which is critical for meiotic recombination and genetically diverse gametes. An international research team reports the application of a TurboID (TbID)-based approach to identify proteins in proximity of meiotic chromosome axes in Arabidopsis thaliana. Not only known but also new meiotic proteins were uncovered.

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Scientists have found that the gut microbiome may modulate the efficacy of CAR-T cellular immunotherpy CAR-T cells in patients with B cell lymphomas. Individualized microbiome information retreaved from patients' gut microbiomes prior to initiation of CAR T therapy could accurately predict their subsequent responsiveness to therapy, but only in the condition that these patients were not pre-treated with broad spectrum antibiotics.

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A whole new world of antibiotics is waiting inside the viruses that infect bacteria. Scientists are making it easier to study them.

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After an earthquake, it is crucial in the early phase of disaster management to obtain a rapid assessment of the severity of the impact on the affected population in order to be able to initiate adequate emergency measures. A first quick and good assessment of whether an earthquake causes severe or minor damage can often be given after only 10 minutes by information from affected people about the 'felt intensity' of the earthquake.

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A new study suggests there may be a layer of surprisingly fluid rock ringing the Earth, at the very bottom of the upper mantle.

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Data captured from seismic waves caused by earthquakes has shed new light on the deepest parts of Earth's inner core, according to seismologists.

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New research on friction between faults could aid in predicting the world's most powerful earthquakes. Researchers discovered that fault surfaces bond together, or heal, after an earthquake. A fault that is slow to heal is more likely to move harmlessly, while one that heals quickly is more likely to stick until it breaks in a large, damaging earthquake. Tests allowed them to calculate a slow, harmless type of tremor. The discovery alone won't allow scientists to predict when the next big one will strike but it does give researchers a valuable new way to investigate the causes and potential for a large, damaging earthquake to happen, and guide efforts to monitor large faults like Cascadia in the Pacific Northwest.

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Cornell University researchers have unearthed precise, microscopic clues to where magma is stored, offering a way to better assess the risk of volcanic eruptions.

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Scientists have discovered a new layer of partly molten rock under the Earth's crust that might help settle a long-standing debate about how tectonic plates move. The molten layer is located about 100 miles from the surface and is part of the asthenosphere, which is important for plate tectonics because it forms a relatively soft boundary that lets tectonic plates move through the mantle. The researchers found, however that the melt does not appear to notably influence the flow of mantle rocks. Instead, they say, the discovery confirms that the convection of heat and rock in the mantle are the prevailing influence on the motion of the plates.

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A 'back-projection' technique reveals new details of the volcanic eruption in Tonga that literally shook the world.

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New findings begin to fill major gaps in understanding about how geological faults behave and appear as they deepen, and they could eventually help lead future researchers to develop better earthquake models on strike-slip faults, regions with frequent and major earthquakes.

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A new study has found that individuals from disadvantaged backgrounds are more likely to experience disaster-related home loss, and they are also more likely to develop functional limitations following the disaster. 

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A machine-learning algorithm reveals the shape of massive subterranean structures linking active volcanoes.

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Researchers suggest how scientists can circumvent the need for massive data sets to forecast extreme events with the combination of an advanced machine learning system and sequential sampling techniques.