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Categories: Biology: Cell Biology, Geoscience: Earthquakes
Published A channel involved in pain sensation can also suppress it
(via sciencedaily.com) Original source Pain is good. It's the body's way to keep an animal from harming itself or repeating a dangerous mistake. But sometimes the debilitating sensation can get in the way. So evolution has devised ways to tamp that response down under certain circumstances.
Published Researchers pinpoint brain cells that drive appetite in obesity
(via sciencedaily.com) Original source A group of brain cells discovered by researchers reveals a potential new approach to anti-obesity treatment.
Published An edible CBD coating could extend the shelf life of strawberries
(via sciencedaily.com) Original source Soon, you'll be able to get a box of freshly picked, sweet strawberries from the grocery store or local farm stand. But it's disappointing when you get them home and find that the ones at the bottom have started to rot. To increase the berries' shelf life, researchers have incorporated cannabidiol -- a non-hallucinogenic compound from cannabis known as CBD -- and sodium alginate into an edible antimicrobial coating.
Published Researchers reveal DNA repair mechanism
(via sciencedaily.com) Original source A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.
Published How superbug A. baumannii survives metal stress and resists antibiotics
(via sciencedaily.com) Original source The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting response. The World Health Organization (WHO) recognizes it as one of the three top pathogens in critical need of new antibiotic therapies. Now, an international team, led by Macquarie University researchers Dr. Ram Maharjan and Associate Professor Amy Cain, have discovered how the superbug can survive harsh environments and then rebound, causing deadly infections. They have found a single protein that acts as a master regulator. When the protein is damaged, the bug loses its superpowers allowing it to be controlled, in a lab setting. The research is published this month in Nucleic Acids Research.
Published Researchers discover brain circuit underlying spontaneous synchronized movement of individuals in groups
(via sciencedaily.com) Original source Individual fish in schools scatter in unison when a predator is in their midst. Such precisely coordinated group movements and immobility during threats have long been observed in insects and mammals. Now, a brain pathway has been discovered that enables individual animals to rapidly coordinate a unified response, with no rehearsal required.
Published Phage structure captured, to benefit biotech applications
(via sciencedaily.com) Original source Researchers have mapped out what a commonly-used form of phage looks like, which will help design better uses in future.
Published Heat-loving marine bacteria can help detoxify asbestos
(via sciencedaily.com) Original source Researchers have shown that extremophilic bacteria from high temperature marine environments can be used to reduce asbestos' toxicity.
Published Researcher uses mammal DNA to zoom into the human genome with unprecedented resolution
(via sciencedaily.com) Original source Scientists have precisely identified base pairs of the human genome that remained consistent over millions of years of mammalian evolution, and which play a crucial role in human disease. The team analyzed the genomes of 240 mammals, including humans and identified base pairs that were 'constrained' -- meaning they remained generally consistent -- across mammal species over the course of evolution. The most constrained base pairs in mammals were over seven times more likely to be causal for human disease and complex trait, and over 11 times more likely when researchers looked at the most constrained base pairs in primates alone.
Published A look inside stem cells helps create personalized regenerative medicine
(via sciencedaily.com) Original source Researchers have examined a specific type of stem cell with an intracellular toolkit to determine which cells are most likely to create effective cell therapies.
Published Ancestral mitoviruses discovered in mycorrhizal fungi
(via sciencedaily.com) Original source A new group of mitochondrial viruses confined to the arbuscular mycorrhizal fungi Glomeromycotina may represent an ancestral lineage of mitoviruses.
Published A journey to the origins of multicellular life: Long-term experimental evolution in the lab
(via sciencedaily.com) Original source Over 3,000 generations of laboratory evolution, researchers watched as their model organism, 'snowflake yeast,' began to adapt as multicellular individuals. In new research, the team shows how snowflake yeast evolved to be physically stronger and more than 20,000 times larger than their ancestor. Their study is the first major report on the ongoing Multicellularity Long-Term Evolution Experiment (MuLTEE), which the team hopes to run for decades.
Published Crops evolved by swapping genetic modules between cells
(via sciencedaily.com) Original source Comparing individual cells across corn, sorghum, and millet reveals evolutionary differences among these important cereal crops, according to a new study. The findings bring researchers closer to pinpointing which genes control important agricultural traits such as drought tolerance, which will help scientists faced with a changing climate adapt crops to drier environments.
Published African rhinos share retroviruses not found in Asian rhinos or other related species
(via sciencedaily.com) Original source Rhinoceros belong to a mammalian order called odd-toed ungulates that also include horses and tapirs. They are found in Africa and Asia. Until recently, evidence suggested that throughout their evolutionary history, gamma-retroviruses such as Murine leukemia virus had not colonized their genomes, unlike most other mammalian orders. The colonization process is called retroviral endogenization and has resulted in most mammalian genomes being comprised of up to ten percent retroviral like sequences.
Published Basic 'toolkit' for organ development is illuminated by sea star
(via sciencedaily.com) Original source One of the basic and crucial embryonic processes to unfold in virtually every living organism is the formation of hollow, tubular structures that go on to form blood vessels or a digestive tract, and through branching and differentiation, complex organs including the heart and kidneys. This study illuminates fundamental design principles of tubulogenesis for all chordates, including mammals.
Published The bat's ability to convert energy into muscle power is affected by flight speed
(via sciencedaily.com) Original source Small bats are bad at converting energy into muscle power. Surprisingly, a new study led by Lund University in Sweden reveals that this ability increases the faster they fly.
Published Scientists create CRISPR-based drug candidate targeting the microbiome
(via sciencedaily.com) Original source A new drug candidate targeting E. coli in the gut is in phase 1 clinical trials. According to a new paper it may improve the well-being of blood cancer patients and reduce their mortality rate from E. coli infections.
Published 'Super-resolution' imaging technology
(via sciencedaily.com) Original source Researchers describe developing a super-resolution imaging platform technology to improve understanding of how nanoparticles interact within cells.
Published Scientists develop gene silencing DNA enzyme that can target a single molecule
(via sciencedaily.com) Original source Researchers have developed a DNA enzyme -- or DNAzyme -- that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact. This breakthrough 'gene silencing' technology could revolutionize the development of DNAzymes for treating cancer, infectious diseases and neurological disorders.
Published T cells can activate themselves to fight tumors
(via sciencedaily.com) Original source Scientists find an auto-signaling mechanism driving the T cell anti-tumor response; findings may inspire new cancer therapeutics and biomarkers.