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Categories: Biology: Biochemistry, Biology: Cell Biology

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LUCA, the 'last universal common ancestor' of all living organisms, lived 4.32 to at most 4.52 billion years ago. What LUCA looked like is unknown, but it must have been a cell with among others ribosomal proteins and an ATP synthase.

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Researchers have used laser-powered ‘optical tweezers’ to reveal a universal motor mechanism used by viruses for packaging their DNA into infectious particles.

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Investigators have played a key role in deciphering a previously unidentified cluster of genes responsible for producing sartorypyrones, a chemical made by the fungal pathogen Aspergillus fumigatus, whose family causes Aspergillosis in humans.

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Scientists have identified the genes in the probiotic Bifidobacteria longum responsible for improving gut motility. A research team found that B. longum strains possessing the abfA cluster of genes can ameliorate constipation through enhanced utilization of an indigestible fiber called arabinan in the gut.

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A new analysis sheds light on the molecular processes involved when a carnivorous species of fungus known as Arthrobotrys oligospora senses, traps and consumes a worm.

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Scientists have discovered that bacteria can create something like memories about when to form strategies that can cause dangerous infections in people, such as resistance to antibiotics and bacterial swarms when millions of bacteria come together on a single surface. The discovery -- which has potential applications for preventing and combatting bacterial infections and addressing antibiotic-resistant bacteria -- relates to a common chemical element bacterial cells can use to form and pass along these memories to their progeny over later generations.  

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A team of researchers found that caffeic-acid based Carbon Quantum Dots (CACQDs), which can be derived from spent coffee grounds, have the potential to protect brain cells from the damage caused by several neurodegenerative diseases.

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Concerted action is required to mitigate the impact of warming on polar ecosystems and sustainably manage these unique habitats.  

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Facemap uses a mouse's facial movements to predict brain activity, bringing researchers one step closer to understanding brain-wide signals driven by spontaneous behaviors.

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Malaria is one of the most widespread and deadly infectious diseases worldwide. New compounds are continuously required due to the risk of malaria parasites becoming resistant to the medicines currently used. A team of researchers has now combined the anti-malaria drug artemisinin with coumarin, which, like artemisinin, is also found in plants, and developed an auto-fluorescent compound from both bioactive substances.

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Researchers think that a flavanol found naturally in red wines can interfere with the proper metabolism of alcohol and can lead to a headache.

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Innovative aquaculture system turns waste wood into nutritious seafood. Researchers hoping to rebrand a marine pest as a nutritious food have developed the world's first system of farming shipworms, which they have renamed 'Naked Clams'.

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The microbiome (the symbiotic community of microbial organisms of a host) is of existential importance for the functioning of every plant and animal, including human beings. A research team has now used the example of the sea anemone Nematostella vectenis to investigate how the microbiome develops together with the host. The researchers describe that the bacterial community is primarily controlled by the host organism during the early stages of life, while bacteria-bacteria interactions play the lead role in subsequent development.

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Biological materials are made of individual components, including tiny motors that convert fuel into motion. This creates patterns of movement, and the material shapes itself with coherent flows by constant consumption of energy. Such continuously driven materials are called 'active matter'. The mechanics of cells and tissues can be described by active matter theory, a scientific framework to understand shape, flows, and form of living materials. The active matter theory consists of many challenging mathematical equations. Scientists have now developed an algorithm, implemented in an open-source supercomputer code, that can for the first time solve the equations of active matter theory in realistic scenarios. These solutions bring us a big step closer to solving the century-old riddle of how cells and tissues attain their shape and to designing artificial biological machines.

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Researchers have determined the gene mutation responsible for an observable trait in bison -- albinism.

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Wild caviar, a pricey delicacy made from sturgeon eggs, has been illegal for decades since poaching brought the fish to the brink of extinction. Today, legal, internationally tradeable caviar can only come from farmed sturgeon, and there are strict regulations in place to help protect the species. However, by conducting genetic and isotope analyses on caviar samples from Bulgaria, Romania, Serbia, and Ukraine -- nations bordering the remaining wild sturgeon populations -- a team of sturgeon experts found evidence that these regulations are actively being broken. Their results show that half of the commercial caviar products they sampled are illegal, and some don't even contain any trace of sturgeon.

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New research  paints an uncharacteristically upbeat picture for the planet. This is because more realistic ecological modelling suggests the world's plants may be able to take up more atmospheric CO2 from human activities than previously predicted.

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After a massive cyclone transformed the ecosystem of Gorongosa National Park, researchers studied the immediate and knock-on impacts to garner lessons for wildlife managers around the world.

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Researchers have uncovered startling connections between micronutrient deficiencies and the composition of gut microbiomes in early life that could help explain why resistance to antibiotics has been rising across the globe. The team investigated how deficiencies in crucial micronutrients such as vitamin A, B12, folate, iron, and zinc affected the community of bacteria, viruses, fungi and other microbes that live in the digestive system. They discovered that these deficiencies led to significant shifts in the gut microbiome of mice -- most notably an alarming expansion of bacteria and fungi known to be opportunistic pathogens. Importantly, mice with micronutrient deficiencies also exhibited a higher enrichment of genes that have been linked to antibiotic resistance.

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Chemists have developed a bioinspired supramolecular approach to convert photo-switchable molecules from their stable state into metastable one with low-energy red light. Their work enables fast, highly selective, and efficient switching, providing new tools for energy storage, activation of drugs with light, and sensing applications.