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Categories: Biology: Cell Biology, Ecology: Invasive Species

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Researchers compare the shield shapes of crabs and find unexpected differentiation.

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Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these therapies get to the patients who will benefit, work is needed to identify the specific mutations behind each patient's disease. Researchers now report several dozen mutations associated with oversensitive toll-like receptors -- a major cause of autoimmune disease -- and linked two mutations to patients.

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Members of the vertebrate group including anglerfishes are unique in possessing a characteristic known as sexual parasitism, in which males temporarily attach or permanently fuse with females to mate. Now, researchers show that sexual parasitism arose during a time of major global warming and rapid transition for anglerfishes from the ocean floor to the deep, open sea.

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A new study predicts future climate change impacts could disrupt the krill-heavy diet that humpback whales in the southern hemisphere consume.

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Community science volunteers -- laypeople with an interest in bees and conservation -- significantly contribute to the scientific knowledge of native bumble bees across Canada and the United States. It's buzz worthy confirmation that community science programs can play an important role in monitoring the changing distributions of bumble bees and more.

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Animals and fungi predominantly use two different modes of cell division -- called open and closed mitosis, respectively. A new study has shown that different species of Ichthyosporea -- marine protists that are close relatives of both animals and fungi -- use either open and closed mitosis, closely correlated to whether the species has multinucleate life cycle stages. The study demonstrates the way animals do cell division might have evolved long before animals themselves did and how this is linked to an organism's life cycle.

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Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.

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A new study shows that real-world ocean conditions make a huge difference in how viral infection affects host bacteria. The findings indicate it is very important to study cells and virocells under nutrient conditions that more closely resemble what they encounter in nature.

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A substance naturally occurring in i.a. pomegranates, strawberries and walnuts can improve memory and treatment of Alzheimer's disease, a new study concludes.

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Researchers describe cell-in-cell phenomena in which one cell engulfs and sometimes consumes another. The study shows that cases of this behavior, including cell cannibalism, are widespread across the tree of life. The findings challenge the common perception that cell-in-cell events are largely restricted to cancer cells. Rather, these events appear to be common across diverse organisms, from single-celled amoebas to complex multicellular animals.

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A new laboratory study suggests that human body lice are more efficient at transmitting Yersinia pestis, the bacterium that causes plague, than previously thought, supporting the possibility that they may have contributed to past pandemics.

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A new study found evidence that Indigenous groups in the Pacific Northwest were intentionally harvesting edible camas bulbs at optimal stages of the plant's maturation as far back as 3,500 years ago.

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Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place? Now, scientists have designed drug-like molecules to do just that, by thwarting the first stage of influenza infection.

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The diversity and ecological functionality of bird communities in tropical agroforestry systems are shaped by the surrounding landscape, in particular the extent and composition of the forest.

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Leishmaniasis is a tropical disease affecting a growing number of people worldwide. Each year, between 700,000 and 1 million new cases are reported. Caused by a protozoan parasite of the genus Leishmania, which is transmitted to humans by the simple bite of a sand fly, leishmaniasis comprises three clinical forms, of which the visceral form is the most serious. If left untreated, visceral leishmaniasis, also known as black fever, is almost always fatal.

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The past attempts of honey bee researchers to inventory the fungal diversity in honey bee colonies revealed that Aspergillus flavus is frequently found in hives. In a new study, researchers have discovered that this fungus is uniquely adapted to survive in bee colonies.

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A new study suggests better nutrition might help prevent cognitive decline. Working with a group of 100 cognitively healthy participants aged 65 to 75, a research team combined neuroscience with nutritional science to identify a specific nutrient profile linked with better performance on cognitive tests. Nutrient biomarkers identified via blood tests revealed a combination of fatty acids, antioxidants and carotenoids, and two forms of Vitamin E and choline -- very similar to the Mediterranean diet -- in the systems of those who showed slower than expected brain aging in MRI scans and cognitive assessments.

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Two new studies detail the changes seen at the single-cell level in pig organs and recipient human bodies before, during, and just after the xenotransplantation surgeries in the decedents.

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Although periodontitis is an extremely prevalent disorder, it is challenging to conduct detailed and comprehensive analyses of its progression at the cellular level. Recently, researchers developed an improved periodontitis mouse model that simplifies the collection and analysis of multiple periodontal tissue types. Using this model, they clarified the role of an important signaling pathway in the inflammatory response of periodontal tissue, paving the way for better diagnostic and therapeutic strategies for periodontitis.

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A recent boom in the purple sea urchin population off the southern Oregon Coast appears to have had an indirect and negative impact on the gray whales that usually forage in the region, a new study shows.