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Categories: Biology: Cell Biology, Ecology: Invasive Species

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Proteins are important molecules that perform a variety of functions essential to life. To function properly, many proteins must fold into specific structures. However, the way proteins fold into specific structures is still largely unknown. Researchers have developed a novel physical theory that can accurately predict how proteins fold. Their model can predict things previous models cannot. Improved knowledge of protein folding could offer huge benefits to medical research, as well as to various industrial processes.

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Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into yeast cells. To tackle this issue, researchers developed an innovative strategy to restore GPCR function in yeast cells by inducing random mutations. Their findings can help understand GPCRs better and could pave the way to therapeutic breakthroughs for many diseases.

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A research team has discovered that parasites manipulate their hosts using stolen genes that they likely acquired through a phenomenon called horizontal gene transfer.

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New soft, implantable fibers can deliver light to major nerves through the body. They are an experimental tool for scientists to explore the causes and potential treatments for peripheral nerve disorders in animal models.

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Researchers have harnessed the power of baker's yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds, and used the new method to identify key enzymes in a kratom tree.

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Study creates a mosquito family tree to better understand disease transmission and host choice.

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A vaccine designed to protect against three different deadly coronaviruses shows success in mouse studies, demonstrating the viability of a pan-coronavirus vaccine developed by researchers at the Duke Human Vaccine Institute.

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A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies.

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Octopuses are fascinating animals -- and serve as important model organisms in neuroscience, cognition research and developmental biology. To gain a deeper understanding of their biology and evolutionary history, validated data on the composition of their genome is needed, which has been lacking until now. Scientists have now been able to close this gap and, in a new study, determined impressive figures: 2.8 billion base pairs -- organized in 30 chromosomes. What sounds so simple is the result of complex, computer-assisted genome analyses and comparisons with the genomes of other cephalopod species.

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A new study finds that greenspace -- the vegetation in a neighborhood's yards, parks and public spaces -- has a positive impact on a key genetic marker associated with exposure to stress. However, the study also finds that the positive impact of greenspace isn't enough to compensate for other environmental challenges, such as air pollution.

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A research group has developed a new method for studying how cancer cells function in softer and stiffer tissue environments. This insight challenges the existing paradigm, opening up new possibilities for research in cancer biology and tissue engineering.

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Using a small bird's nest-making process as a model, researchers have developed a nontoxic process for making cellulose gels. 

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Whaling in the 20th century destroyed 99% of the Eastern North Pacific fin whale breeding population. Because there is enough genetic diversity, current conservation measures should help the population rebound without becoming inbred. The future of fin whales in the Gulf of California depends on the recovery of the Eastern North Pacific population.

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Because the bumblebee that an orchid relies on for pollination does not exist on a remote island, the plant gets pollinated by an island wasp. Researchers found that this came at the cost of being hybridized with another orchid species adapted to being pollinated by the wasp. The finding showcases how plants in ecological relationships adapt to changing circumstances.

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Researchers say mapping the genetic code of the brushtail possum will benefit those working to both conserve and control the animal.

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The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location of imperfect complementary sequences. Fluorescent markers bound to one of the matching DNA strands make the duplex visible, and fluorescence intensity increases with increasing duplex stability. Now, researchers have succeeded in creating fluorescent duplexes that can generate any of 16 million colors -- a work that surpasses the previous 256 colors limitation. This very large palette can be used to 'paint' with DNA and to accurately reproduce any digital image on a miniature 2D surface with 24-bit color depth.

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Now is the time to identify the conditions that cause plants to die. Doing so will allow us to better protect plants by choosing conservation targets more strategically, botanists argue.

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Using cryo-electron microscopy (cryo-EM), researchers captured unprecedented images of key immune system receptors interacting with messenger proteins, elucidating how the receptors change shape upon activation and transmit signals within the cell. The findings suggest new pathways for developing therapeutic molecules for diseases such as COVID-19, rheumatoid arthritis, neurodegenerative diseases and cancer.

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As Halloween approaches, so too does the anticipation of a trick-or-treating stash filled with fun-sized chocolate candy bars. But to satisfy our collective craving for this indulgence, millions of cocoa pods are harvested annually. While the beans and pulp go to make chocolate, their husks are thrown away. Now, researchers show that cocoa pod husks could be a useful starting material for flame retardants.

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Researchers say they have found 'definitive' archaeological evidence that seaweeds and other local freshwater plants were eaten in the mesolithic, through the Neolithic transition to farming and into the Early Middle Ages, suggesting that these resources, now rarely eaten in Europe, only became marginal much more recently.