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Categories: Biology: Cell Biology, Ecology: Trees
Published Genomic research may help explain cancer resistance in Tasmanian devils
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Through DNA sequencing of Tasmanian devils and their tumors, researchers have tracked the genomic interactions between the animals and the cancer.
Published New imaging method illuminates oxygen's journey in the brain
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A new bioluminescence imaging technique has created highly detailed, and visually striking, images of the movement of oxygen in the brains of mice. The method, which can be easily replicated by other labs, will enable researchers to more precisely study forms of hypoxia in the brain, such as the denial of oxygen to the brain that occurs during a stroke or heart attack. The new research tool is already providing insight into why a sedentary lifestyle may increase risk for diseases like Alzheimer's.
Published Researchers discover key gene for toxic alkaloid in barley
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Barley is one of the most important cereal crops on a global scale. Many barley cultivars produce a toxic alkaloid called gramine that affects the suitability of barley as fodder, but also helps to protect barley from pathogens. So far, the potential of manipulating gramine levels has not been harnessed for plant breeding, because the genetic basis of gramine production has been unresolved. Research groups now disclose the complete biosynthetic pathway of gramine and demonstrate how gramine biosynthesis can be introduced into model organisms or removed from barley.
Published Cell division quality control 'stopwatch' uncovered
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Biologists have uncovered a quality control timing mechanism tied to cell division. The 'stopwatch' function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.
Published Eggs may not be bad for your heart after all
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Whether you like your eggs sunny-side up, hard boiled or scrambled, many hesitate to eat them amid concerns that eggs may raise cholesterol levels and be bad for heart health. However, results from a prospective, controlled trial show that over a four-month period cholesterol levels were similar among people who ate fortified eggs most days of the week compared with those who didn't eat eggs.
Published Connecting the dots to shape growth forces
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Branching patterns are prevalent in our natural environment and the human body, such as in the lungs and kidneys. For example, specific genes that express growth factor proteins are known to influence the development of the lungs' complex branches. Researchers have unveiled a regulatory system linking signal, force, and shape in mouse lung structure development. The team recognized that the signal protein ERK plays an active role in causing growing lung tissue to curve.
Published Synaptic protein change during development offers clues on evolution and disease
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An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The findings offer first insights into the mechanism behind synaptic development and open up routes for research on possible treatments.
Published New method developed to isolate HIV particles
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Researchers have developed a new method to isolate HIV from samples more easily, potentially making it easier to detect infection with the virus. They focus on peptide nanofibrils (PNFs) on magnetic microparticles, a promising tool and hybrid material for targeted binding and separation of viral particles.
Published A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis
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Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of anti-microbial medications to kill tuberculosis bacteria residing in the lungs.
Published Scientists extract genetic secrets from 4,000-year-old teeth to illuminate the impact of changing human diets over the centuries
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Researchers have recovered remarkably preserved microbiomes from two teeth dating back 4,000 years, found in an Irish limestone cave. Genetic analyses of these microbiomes reveal major changes in the oral microenvironment from the Bronze Age to today. The teeth both belonged to the same male individual and also provided a snapshot of his oral health.
Published New technique for predicting protein dynamics may prove big breakthrough for drug discovery
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Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple protein configurations to advance understanding of protein dynamics and functions.
Published Combination of the climate crisis and continued deforestation may result in significant damage to the animal world
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A new study states that the combination of global warming and extreme heat events, alongside the continued expansion of deforestation in the world, may be devastating for many species of animals, especially those that know how to climb trees. As part of the study, the researchers focused on lizards and showed that following the effects of climate change, they will seek refuge from the hot ground by spending a lot of time on trees. However, due to human-related activities, such as deforestation, urbanization and the expansion of agricultural lands at the expense of natural lands, the availability of trees in the areas where the lizards live will decrease, and this may lead to the collapse of many populations.
Published New enzymatic cocktail can kill tuberculosis-causing mycobacteria
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An enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.
Published Milk on ice: Antarctic time capsule of whole milk powder sheds light on the enduring qualities--and evolution--of dairy products past and present
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In a remarkable discovery, whole milk powder manufactured in New Zealand in 1907 and transported to Antarctica with explorers seeking the South Pole was unveiled after more than a century. The find has allowed dairy researchers to answer the question: Is the milk we enjoy today different from the milk consumed in previous generations? Now, a new comparative study has peered back in time to demonstrate that -- despite advancements in selective breeding and changes to farm practices -- milk of the past and milk today share more similarities than differences and are still crucial building blocks of human nutrition.
Published Old immune systems revitalized in mouse study, improving vaccine response
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Those with aging immune systems struggle to fight off novel viruses and respond weakly to vaccination. Researchers were able to revitalize the immune system in mice.
Published Super permeable wearable electronics developed for stable, long-term biosignal monitoring
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Super wearable electronics that are lightweight, stretchable and increase sweat permeability by 400-fold have been developed by scientists, enabling reliable long-term monitoring of biosignals for biomedical devices.
Published New testing approach improves detection of rare but emerging Powassan virus spread by deer ticks
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Researchers have come up with a new, more accurate method for detecting in ticks the emerging Powassan virus, which can cause life-threatening neuroinvasive disease, including encephalitis and meningitis.
Published Researchers find energy development and tree encroachment impact Wyoming pronghorn
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While Wyoming is home to some of North America's most abundant populations of pronghorn that have largely been stable in recent years, a new analysis shows that many herds are experiencing long-term declines in fawn production.
Published Researchers show that introduced tardigrade proteins can slow metabolism in human cells
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Tardigrade proteins are potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.
Published Discovery of amino acid unveils how light makes plants open
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Scientists have uncovered a unique mechanism that regulates the opening of stomata in plants. Phosphorylation of the amino acid Thr881 on the plasma membrane proton pump plays a key role in this process. The study paves the way for the targeted manipulation of plant physiology, with potential applications in agriculture and environmental sustainability.