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Categories: Biology: Cell Biology, Physics: General

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The very first life on earth is thought to have developed from 'protocells' -- liquid mixtures of many different types of molecules. Researchers have now shown that in such mixtures, small imbalances in the number of molecules of different types can have an unexpected effect. A surprising interplay with the complex pattern of interactions strongly amplifies such imbalances -- meaning that a type of molecule that is only slightly in the majority can almost entirely separate out from the others. These fundamental findings point towards a new mechanism that will apply in many complex mixtures. For instance, this would be a way for cells to control the formation of structures by fine-tuning the concentration of different molecules.

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HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops. These reservoirs have long been thought to be dormant, but two independent groups of researchers report that a subset of these cells spontaneously produce HIV RNA and proteins that may impact patients' HIV-specific immune responses.

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A chemist drew inspiration from the natural world, from his experiences scuba diving to studying shellfish in his lab. He has developed a sustainable adhesive system -- an alternative to toxic, permanent, traditional adhesives.

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A new article uses environmental DNA (eDNA) metabarcoding to analyze fish and zooplankton communities. The study found that the movement of water between freshwater bodies, or freshwater connectivity, can transport eDNA. This highlights the potential of eDNA to provide a comprehensive view of freshwater biodiversity.

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Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet.

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Researchers have uncovered new genetic insights into Staphylococcus aureus, revealing what makes the bacterium so dangerous when it enters the blood.

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Researchers have invented a nano-thin superbug-slaying material that could one day be integrated into wound dressings and implants to prevent or heal bacterial infections. The innovation -- which has undergone advanced pre-clinical trials -- is effective against a broad range of drug-resistant bacterial cells, including 'golden staph', which are commonly referred to as superbugs.

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Physicists begin to shed light on one of the most important questions regarding quantum spin liquids, and they do so by introducing a new phase of matter.

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New findings indicate that the type of protein in the diet is not as important as the overall amount of weight loss for those with Type 2 diabetes. 106 adults with T2D were randomly assigned to either the high-protein or normal-protein diet for 52 weeks. Both diets were energy-restricted. The high-protein diet included recommendations to include lean beef in the diet, while the normal-protein diet instructed participants to refrain from eating any red meats. The team of researchers found that both a high-protein diet (40 percent of total calories from protein) and a moderate-protein diet (21 percent of total calories from protein) were effective in improving glucose control, weight loss and body composition in people with Type 2 diabetes.

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Coffee could be the key to reducing 3D printing waste, according to a new study. Researchers have developed a method for 3D printing using a paste made out of old coffee grounds.

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Biologists have found evidence for evolutionary 'syndromes'-- sets of traits that occur together -- that help to explain how tomatoes first evolved their distinctive blend of color, sweetness, acidity and aroma. The research not only shines a light on how fruits evolve in the wild, but will also be valuable to crop-improvement efforts aimed at breeding more nutritious and appealing varieties of fruits.

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More than 400 million years ago, an insect-like animal called the springtail developed a small protein that prevents its cells from freezing.

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Researchers are one step closer to making the T cell army stronger. In a recent study, researchers found that by manipulating one molecular signaling pathway in the T cells that participate in clearing influenza virus in the lungs, the strength and longevity of immunological memory produced can be improved.

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Root hairs represent a low-cost strategy to enhance nutrient uptake because they can significantly increase the nutrient-acquiring surface of plant roots. While primary and lateral roots are stimulated to elongate when plants grow under mild nitrogen deficiency, the existence of such a foraging response for root hairs and its underlying regulatory mechanism remain elusive. Now, researchers have revealed a framework composed of specific molecular players meditating auxin synthesis, transport and signaling that triggers root hair elongation for nitrogen acquisition.

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Genomic surveillance has revealed mutations in malaria-causing parasites that will complicate efforts to eradicate the disease in Africa.

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A research team has created an aluminum-nitride device that can convert visible light into deep-ultraviolet light through the process of second harmonic generation. This work can lead to the development of practical devices that can sterilize surfaces with ultraviolet radiation while using less energy.

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Using laser light, researchers have developed the most robust method currently known to control individual qubits made of the chemical element barium. The ability to reliably control a qubit is an important achievement for realizing future functional quantum computers.

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Researchers have unveiled an intriguing phenomenon of cellular reprogramming in mature adult organs, shedding light on a novel mechanism of adaptive growth. The study, which was conducted on fruit flies (Drosophila), provides further insights into dedifferentiation -- where specialized cells that have specific functions transform into less specialized, undifferentiated cells like stem cells.

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Researchers have developed a new imaging technique to observe active gene expression in real time. They found that four molecules work together to control the timing of each stage of the C. elegans worm's development. This timekeeping process could provide important clues about the natural rhythm of development in humans and other animals.

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In a breakthrough for the field of bioelectronics, researchers have enhanced the ability of E. coli bacteria to generate electricity. The innovative approach only offers a sustainable solution for organic waste processing while outperforming previous state-of-the-art technologies, opening new horizons for versatile microbial electricity production.