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Categories: Biology: Cell Biology, Energy: Technology
Published Tiny sea creatures reveal the ancient origins of neurons
(via sciencedaily.com) Original source A new study sheds new light on the origins of modern brain cells. Researchers find evidence that specialized secretory cells found in placozoans, tiny sea creatures the size of a grain of sand, have many similarities to the neuron, such as the genes required to create a partial synapse. From an evolutionary point of view, early neurons might have started as something like these cells, eventually gaining the ability to create a complete synapse, form axons and dendrites and create ion channels that generate fast electrical signals -- innovations which gave rise to the neuron in more complex animals such as jellyfish. Though the complete story of how the first neuron appeared remains to be told, the study demonstrates that the basic building blocks for our brain cells were forming in the ancestors of placozoans grazing inconspicuously in the shallow seas of Earth around 800 million years ago.
Published RNA for the first time recovered from an extinct species
(via sciencedaily.com) Original source A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This resulted in the reconstruction of skin and skeletal muscle transcriptomes from an extinct species for the first time. The researchers note that their findings have relevant implications for international efforts to resurrect extinct species, including both the Tasmanian tiger and the woolly mammoth, as well as for studying pandemic RNA viruses.
Published Predictive model could improve hydrogen station availability
(via sciencedaily.com) Consumer confidence in driving hydrogen-fueled vehicles could be improved by having station operators adopt a predictive model that helps them anticipate maintenance needs, according to researchers.
Published Tracking down the formation of cardenolides in plants
(via sciencedaily.com) Original source Scientists are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants. In a new study, they present two enzymes from the CYP87A family as key enzymes that catalyze the formation of pregnenolone, the precursor for the biosynthesis of plant steroids, in two different plant families. The discovery of such enzymes should help to develop platforms for the cheap and sustainable production of high quality steroid compounds for medical use.
Published Golden future for thermoelectrics
(via sciencedaily.com) Researchers discover excellent thermoelectric properties of nickel-gold alloys. These can be used to efficiently convert heat into electrical energy.
Published That smell: New gut microbe produces smelly toxic gas but protects against pathogens
(via sciencedaily.com) Original source Microbiologists have discovered a new intestinal microbe that feeds exclusively on taurine and produces the foul-smelling gas hydrogen sulfide. The researchers have thus provided another building block in the understanding of those microbial processes that have fascinating effects on health. This is also true of Taurinivorans muris: the bacterium shows a protective function against Klebsiella and Salmonella, two important pathogens.
Published Brain-altering parasite turns ants into zombies at dawn and dusk
(via sciencedaily.com) Original source It takes over the brains of ants, causing them to cling to blades of grass against their will. The lancet liver fluke has an exceptional lifecycle strategy, in which snails, ants and grazing animals are unwitting actors. Researchers now reveal more about the mind-bending workings of this tiny parasite.
Published Mitochondrial genome editing technique yields useful traits
(via sciencedaily.com) Original source Tweaks to the mitochondrial genome hold the potential for better hybrid seed production or to introduce seedless fruits.
Published Living in a disadvantaged neighborhood affects food choices, weight gain and the microstructure of the brain
(via sciencedaily.com) Original source A new study finds poor quality of available foods, increased intake of calories from foods high in trans-fatty acids, and environments that do not foster physical activity, all prevalent in disadvantaged neighborhoods, disrupt the flexibility of information processing in the brain that is involved in reward, emotion regulation, and cognition.
Published Genome editing: Reducing off-target mutations in DNA
(via sciencedaily.com) Original source Researchers have developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded 'nicks' in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.
Published Genetically modified bacteria break down plastics in saltwater
(via sciencedaily.com) Original source Researchers have genetically engineered a marine microorganism to break down plastic in salt water. Specifically, the modified organism can break down polyethylene terephthalate (PET), a plastic used in everything from water bottles to clothing that is a significant contributor to microplastic pollution in oceans.
Published Using topology, Researchers advance understanding of how cells organize themselves
(via sciencedaily.com) Original source R esearchers created a machine learning algorithm using computational topology that profiles shapes and spatial patterns in embryos to study how these cells organize themselves into tissue-like architectures. In a new study, they take that system to the next level, opening a path to studying how multiple types of cells assemble themselves.
Published Specialized gut immune cells pinpointed that can limit progression of inflammatory bowel disease
(via sciencedaily.com) Original source Researchers have characterized a specialized type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.
Published Researchers discover tissue-specific protection against protein aggregation
(via sciencedaily.com) Original source Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail. By understanding how different tissues tackle protein build up, this research could accelerate the identification of ways to protect tissues that are vulnerable to protein build up, possibly tackling both disease-associated protein aggregates and also age-dependent aggregates that accelerate the functional decline of tissues.
Published Researchers make strides in harnessing low-grade heat for efficient energy conversion
(via sciencedaily.com) A research team has achieved significant breakthroughs in harnessing low-grade heat sources (<100 °C) for efficient energy conversion.
Published From hagfish to membrane: Modeling age-related macular degeneration
(via sciencedaily.com) Original source Researchers have successfully demonstrated that hagfish slime proteins can accurately replicate membranes in the human eye. Scientists were able to properly grow retinal cells on hagfish slime proteins and prove that the protein's behavior changes as the membrane mimics stages of aging and disease.
Published Battery-free robots use origami to change shape in mid-air
(via sciencedaily.com) Researchers have developed small robotic devices that can change how they move through the air by 'snapping' into a folded position during their descent. Each device has an onboard battery-free actuator, a solar power-harvesting circuit and controller to trigger these shape changes in mid-air.
Published Flu: Interferon-gamma from T follicular helper cells is required to create lung-resident memory B cells
(via sciencedaily.com) Original source During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body. One path is the B cells that differentiate into lung-resident memory B cells, or lung-BRMs, that are critical for pulmonary immunity. These long-lived, non-circulating lung-BRMs migrate to the lungs from draining lymph nodes and reside there permanently as the first layer of defense that can quickly react to produce antibodies in a future infection.
Published Electrifying vehicles in Chicago would save lives, reduce pollution inequities
(via sciencedaily.com) If the Chicago region replaced 30% of all on-road combustion-engine vehicles -- including motorcycles, passenger cars and trucks, buses, refuse trucks and short- and long-haul trucks -- with electric versions, it would annually save more than 1,000 lives and over $10 billion, according to a new study.
Published Mysterious family of microbial proteins hijack crops' cellular plumbing
(via sciencedaily.com) Original source Some crop pathogens use a clever trick to multiply and spread infection: they hijack the plant's cellular plumbing. In a new study, researchers unveil a class of bacterial proteins that fold into a straw-like shape and insert themselves into the plant cell membrane, allowing the inside of the leaf to become waterlogged. The researchers also figured out a possible way to block the water channel proteins and prevent infection.