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Categories: Biology: Biotechnology, Paleontology: General

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A team of researchers reconstructed long-extinct proteins of a UV protection system of cyanobacteria. The surprising result: the proteins were already compatible with each other when they first met. This discovery expands the knowledge horizon on the rules of evolution.

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Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study. Investigators now report on the creation of embryo-like structures from monkey embryonic stem cells. The investigators also transferred these embryo-like structures into the uteruses of female monkeys and determined that the structures were able to implant and elicit a hormonal response similar to pregnancy.

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People with Alzheimer's disease develop defects in cognitive functions like memory as well as problems with noncognitive functions that can lead to anxiety and depression. Investigators used mice to study a process through which new neurons are generated in adulthood, called adult hippocampus neurogenesis (AHN). The research showed that deep brain stimulation of new neurons helped restore both cognitive and noncognitive functions in mouse models of Alzheimer's disease.

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Scientists have found that human ribosomes decode mRNA slower than bacteria, with implications for drug development.

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Ice sheets can retreat up to 600 meters a day during periods of climate warming, 20 times faster than the highest rate of retreat previously measured. An international team of researchers used high-resolution imagery of the seafloor to reveal just how quickly a former ice sheet that extended from Norway retreated at the end of the last Ice Age, about 20,000 years ago.

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In a twist on the question, 'Which came first, the chicken or the egg?', scientists have long faced a similar question about how human adenovirus replicates: 'Which comes first, assembly of the viral particle, or packaging of the viral genome?' Now, in a new study, scientists have answered that question, showing that viral proteins use a process called phase separation to coordinate production of viral progeny.

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A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases.

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Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

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An international research team has determined that Troodon, a dinosaur very close to modern birds, was a warm-blooded animal (an endotherm), but had a reproductive system similar to that of modern reptiles. The scientists applied a new method which allowed for accurate determination of the temperature when the egg's carbonate shell was formed. Furthermore, the researchers showed that Troodon laid 4 to 6 eggs per clutch. As nests with up to 24 Troodon eggs had been found, the scientists conclude that several Troodon females laid their eggs in communal nests.

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Researchers have discovered, using a recently developed technology, that genetically identical cells within a bacterial community have different functions, with some members behaving more docile and others producing the very toxins that make us feel ill.

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A family of 'promiscuous' proteins found in all land plants is responsible for many different plant functions, despite remaining relatively unchanged for over 450 million years.

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A lower body temperature is one of the most effective mechanisms to prolong the lifespan of animals. New research has now described precisely how this works. The scientists show that cold can prevent the pathological aggregation of proteins typical for two aging-associated neurodegenerative diseases.

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Wastewater is a more potent environment for antibiotic resistance to evolve than previously known. A study shows that wastewaters have unique characteristics, allowing resistance genes to start their journey from harmless bacteria to those that cause disease.

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Researchers have succeeded in developing an E. coli-based 'smart microbe' that secretes therapeutic payloads, including antibodies, into the gut. The genetically modified beneficial strain of bacteria blocks intestinal inflammation in a preclinical model of inflammatory bowel disease and has the potential to treat intestinal-based diseases.

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Researchers have developed a technology for delivering a microrobot to a target point of a hippocampus in an in-vitro environment, connecting neural networks, and measuring neural signals. The findings are expected to contribute to neural network research and the verification and analysis of cell therapy products.

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Shigella bacteria can infect humans but not mice. A team can now explain why. Their findings may explain the multifariousness of a key weapon of our immune system.

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A new study suggests that predatory dinosaurs, such as Tyrannosaurus rex, did not have permanently exposed teeth as depicted in films such as Jurassic Park, but instead had scaly, lizard-like lips covering and sealing their mouths.

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Aging cells express a protein that is produced by human cytomegalovirus and is targeted by certain immune cells in the body. Harnessing the immune response to this protein could have multiple health benefits during aging.

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The fruit of the cocklebur plant, which grows worldwide and is often considered a noxious weed, has antioxidant and anti-inflammatory components that could make it useful as a skin protectant, according to new research.

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The Indo-West Pacific is the largest marine ecosystem on Earth, but scientists who study its diversity have to contend with a problem so well-known it was remarked upon by Charles Darwin: related species in the IWP have similar appearances, making it difficult to assess just how many there are. A new study reveals that nearly identical crab species have one consistently distinguishing feature, which only evolves when their ranges overlap.