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Categories: Biology: Biotechnology, Geoscience: Environmental Issues

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Many natural substances possess interesting characteristics, and can form the basis of new active compounds in medicine. Terpenes, for example, are a group of substances, some of which are already used in therapies against cancer, malaria or epilepsy. They are found as fragrances in cosmetics or as flavorings in food, and form the basis of new medications: Terpenes are natural substances that occur in plants, insects and sea sponges. They are difficult to produce synthetically. However, chemists are now introducing a new method of synthesis.

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Researchers have deciphered the complex interplay of various enzymes around the innate immune receptor toll-like receptor 7 (TLR7), which plays an important role in defending our bodies against viruses.

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The alarming rates of biodiversity loss worldwide have made clear that the classical way of governing biodiversity recovery based on protected areas and programs for the protection of endangered species is not enough. To tackle this, almost 200 countries committed to the active 'mainstreaming' or integration of biodiversity targets into policies and plans across relevant sectors. However, research suggests that this has until now been largely ineffective due to non-binding commitments, vaguely formulated targets, 'add-on' biodiversity initiatives, and too few resources. 'Top down regulation is also needed,' say the authors.

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The length of telomeres in white blood cells, known as leukocytes, varies significantly among sub-Saharan African populations, researchers report. Moreover, leukocyte telomere length (LTL) is negatively associated with malaria endemicity and only partly explained by genetic factors.

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A parasite that not only feeds of its host, but also makes the host change its own metabolism and thus biology. Microbiologists have shown this for the very first time in a specific group of parasitic microbes, so-called DPANN archea. Their study shows that these archaea are very 'picky eaters', which might drive their hosts to change the menu.

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The Environmental Protection Agency (EPA) is underestimating methane emissions from landfills, urban areas and U.S. states, according to a new study. The researchers combined 2019 satellite observations with an atmospheric transport model to generate a high-resolution map of methane emissions, which was then compared to EPA estimates from the same year. The researchers found: Methane emissions from landfills are 51% higher compared to EPA estimates Methane emissions from 95 urban areas are 39% higher than EPA estimates Methane emissions from the 10 states with the highest methane emissions are 27% higher than EPA estimates.

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Viruses known as 'jumbo' phages are seen as a potential tool against deadly bacterial infections. But scientists must first decipher the extraordinary makeup of these mysterious viruses. Researchers have now uncovered a key piece of jumbo phage development that helps them counter bacteria.

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A study describes a new computer algorithm which can be applied to Earth System Models to drastically reduce the time needed to prepare these in order to make accurate predictions of future climate change. During tests on models used in IPCC simulations, the algorithm was on average 10 times faster at spinning up the model than currently-used approaches, reducing the time taken to achieve equilibrium from many months to under a week.

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Researchers have discovered the missing piece of the puzzle behind a rare opening in the sea ice around Antarctica, which was nearly twice the size of Wales and occurred during the winters of 2016 and 2017. A study reveals a key process that had eluded scientists as to how the opening, called a polynya, was able to form and persist for several weeks.

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Reaching net-zero carbon emissions goals requires finding transformative paths to manage carbon in difficult-to-electrify economic sectors.

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Scientists are harnessing cells to make new types of materials that can grow, repair themselves and even respond to their environment. These solid 'engineered living materials' are made by embedding cells in an inanimate matrix that's formed in a desired shape. Now, researchers have 3D printed a bioink containing plant cells that were then genetically modified, producing programmable materials. Applications could someday include biomanufacturing and sustainable construction.

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With recent studies having established the presence of nano and microplastic particles in the respiratory systems of both human and bird populations, new research has modeled what happens when people breathe in different kinds of plastic particles and where they end up.

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Conventional plant regeneration approaches by cell culture require the external application of plant growth regulators, including hormones. However, optimizing culture conditions can be laborious. Now, researchers have developed a novel plant regeneration system that omits the need for hormone application by genetically regulating the expression of genes that control plant cell differentiation. Their work holds significant potential in the development of genetically modified plants in a simpler and cost-effective manner.

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Common household products containing nanoparticles -- grains of engineered material so miniscule they are invisible to the eye -- could be contributing to a new form of indoor air pollution, according to a new study.

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Carbon emissions associated with air travel to professional conferences make up a sizable fraction of the emissions produced by researchers in academia.

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Researchers have unveiled evidence for ancient human resilience to climate change in the Eastern Mediterranean.

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Evapotranspiration (ET) includes evaporation from soil and open water pools such as lakes, rivers, and ponds, as well as transpiration from plant leaves. The difference between precipitation and ET indicates the water balance available for societal needs, including agricultural and industrial production. However, measuring ET is challenging. A new study presents a computer model that uses artificial intelligence (AI) for ET prediction based on remote sensing estimates.

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The link between massive flood basalt volcanism and the end-Triassic (201 million years ago) mass-extinction is commonly accepted. However, exactly how volcanism led to the collapse of ecosystems and the extinction of entire families of organisms is difficult to establish. Extreme climate change from the release of carbon dioxide, degradation of the ozone layer due to the injection of damaging chemicals, and the emissions of toxic pollutants, are all seen as contributing factors. One toxic element stands out: mercury.

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A team of researchers has investigated the motivation and potential incentives for and challenges of low-intensity grazing among farmers and land users in Europe.

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Researchers have developed a chemical process using plasma that could create sustainable jet fuel from methane gas emitted from landfills, potentially creating a low-carbon aviation industry.