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Categories: Biology: Biotechnology, Geoscience: Environmental Issues

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Researchers have discovered that the mere act of attaching their microparticle 'backpacks' to neutrophils is enough to activate them against cancer -- no drugs needed. In experiments, backpack-bearing neutrophils shrank tumors and extended the survival of mice with cancer, and treated animals retained an immune memory of the disease. This approach opens the door to a new class of drug-free immunotherapy for cancer.

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Human sweat contains a protein that may protect against Lyme disease. About one-third of the population carries a genetic variant of this protein that is associated with Lyme disease in genome-wide association studies.

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Namibia's legendary fairy circles are mysterious, circular, bald patches in the dry grasslands on the edge of the Namib Desert. Their formation has been researched for decades and has recently been the subject of much debate. With extensive fieldwork, researchers investigated how freshly germinated grass dies inside the fairy circle. Their results show that the grass withers due to a lack of water inside the fairy circle. The topsoil, comprised of the top 10 to 12 centimeters of the soil, acts as a kind of 'death zone' in which fresh grass cannot survive for long.

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To better understand a carbon sink in danger, scientists are turning to tiny organisms that have long been overlooked.

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A new report uncovers how hydrogen gas, the energy of the future, provided energy in the past, at the origin of life 4 billion years ago. Hydrogen gas is clean fuel. It burns with oxygen in the air to provide energy with no CO2. Hydrogen is a key to sustainable energy for the future. Though humans are just now coming to realize the benefits of hydrogen gas (H2 in chemical shorthand), microbes have known that H2 is good fuel for as long as there has been life on Earth. Hydrogen is ancient energy.

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When climate scientists look to the future to determine what the effects of climate change may be, they use computer models to simulate potential outcomes such as how precipitation will change in a warming world. Some scientists are also looking at something a little more tangible: coral.

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The development of hair was of central importance for the evolution of mammals and thus also of humans. However, the evolutionary origin of the genetic program of hair was previously unknown. Researchers have now been able to show that important hair components and their genetic control have already evolved in amphibians. Human hair therefore shows unexpected similarities to the claws of clawed frogs.

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A new study has found a decline in the abundance of marine fish species that move rapidly toward the poles to escape rising sea temperatures. The researchers explain that many animal species are currently moving toward cooler regions as a result of global warming, but the velocity of such range shifts varies greatly for different species. Examining thousands of populations from almost 150 fish species, the researchers show that contrary to the prevailing view, rapid range shifts coincide with widescale population declines.

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Research is exploring how to add value to lignin by breaking it down into small molecules that are structurally similar to oxygenated hydrocarbons. These renewable chemicals are key components in many industrial processes and products, but they are traditionally sourced from non-renewable petroleum.

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The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.

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Researchers recently reported on the science behind its special concrete, that can warm itself up when it snows, or as temperatures approach freezing.

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Depicting worst-case climate scenarios like expanding deserts and dying coral reefs may better motivate people to support environmental policies when delivered via virtual reality, according to a research team that studied how VR and message framing affect the impact of environmental advocacy communications. The study findings may help advocacy groups decide how best to frame and deliver their messages.

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In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.

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There's a new metric that provides a more holistic look at how much water is stored in snowpack, and for how long.

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Researchers have created a DNA origami platform called DoriVac, whose core component is a self-assembling square block-shaped nanostructure. DoriVac vaccines enabled tumor-bearing mice to better control the growth of tumors and to survive significantly longer than control mice.

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In order to limit the increase in global average temperature to 1.5 C, it is essential to drastically reduce carbon dioxide emissions in the atmosphere. This would mean not exploiting most of the existing coal, conventional gas and oil energy resources in regions around the world, according to new research. The study presents the atlas of unburnable oil in the world, a world map designed with environmental and social criteria that warns which oil resources should not be exploited to meet the commitments of the Paris Agreement signed in 2015 to mitigate the effects of climate change.

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Perfectly adapted microorganisms live in extreme environments from deep-sea trenches to mountaintops. Learning more about how these extremophiles survive in hostile conditions could inform scientists about life on Earth and potential life on other planets.

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Automated insulin dosing systems combine low-cost blood-glucose monitors with insulin pumps that use precision dosing to continuously regulate blood-sugar and hold it steady. Synthetic biologists have found a way to piggyback on the technology and make it universally applicable for the precision dosing of virtually any drug.

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Restored salmon habitat should resemble financial portfolios, offering fish diverse options for feeding and survival so that they can weather various conditions as the climate changes, a new study shows.

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In examining the mating rituals of roundworms, researchers uncovered a unique approach to reproduction that maximizes genetic fitness.