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Categories: Biology: Biotechnology, Space: Astrophysics

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A groundbreaking study has found that evolution is not as unpredictable as previously thought, which could allow scientists to explore which genes could be useful to tackle real-world issues such as antibiotic resistance, disease and climate change. The study challenges the long-standing belief about the unpredictability of evolution, and has found that the evolutionary trajectory of a genome may be influenced by its evolutionary history, rather than determined by numerous factors and historical accidents.

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Astronomers believe they may have found the origin of the universe's giant odd radio circles: they are shells formed by outflowing galactic winds, possibly from massive exploding stars known as supernovae.

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Creating a functional lung using interspecies chimeric animals is an attractive albeit challenging option for lung transplantation, requiring more research on the viable conditions needed for organ generation. A new study uses reverse-blastocyst complementation and tetraploid-based organ complementation methods to first determine these conditions in lung-deficient mice and then to generate rat-derived lungs in these mice. It provides useful insights on the intrinsic species-specific barriers and factors associated with lung development in interspecies chimeric animals.

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Scientists have created analogs of the antibiotic spectinomycin that are significantly more effective against these highly resistant bacteria.

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Scientists have engineered the microbiome of plants for the first time, boosting the prevalence of 'good' bacteria that protect the plant from disease. The findings could substantially reduce the need for environmentally destructive pesticides.

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A research team has detected various substances that have a dual effect against tuberculosis: They make the bacteria causing the disease less pathogenic for human immune cells and boost the activity of conventional antibiotics.

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Biologists developed a method for illuminating the intricate interactions of the synaptonemal complex in the nematode C. elegans. The authors identified a trio of protein segments that guide chromosomal interactions, and pinpointed the location where they interact with each other. Their novel method uses a technique known as genetic suppressor screening, which can serve as a blueprint for research on large cellular assemblies that resist traditional structural analysis.

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Researchers have determined how Eastern equine encephalitis virus attaches to a receptor it uses to enter and infect cells. The findings laid the groundwork for a receptor decoy molecule that protects mice from encephalitis caused by the virus.

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Many bacterial pathogens use small injection apparatuses to manipulate the cells of their hosts, such as humans, so that they can spread throughout the body. To do this, they need to fill their syringes with the relevant injection agent. A technique that tracks the individual movement of proteins revealed how bacteria accomplish this challenging task.

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We don't know how magnetic fields in the cosmos formed. Now a new theoretical research tells how the invisible part of our universe could help us find out, suggesting a primordial genesis, even within a second of the Big Bang.

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A new study to motivate your New Year's resolutions: it demonstrates that high-fat diets negatively impact genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system and brain function.

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A new study has revealed the chemical bonding behind sodium's high-pressure transformation from shiny metal to transparent insulator.

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New theoretical analysis places the likelihood of massive neutron stars hiding cores of deconfined quark matter between 80 and 90 percent. The result was reached through massive supercomputer runs utilizing Bayesian statistical inference.

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A whirling image features a bright spiral galaxy known as MCG-01-24-014, which is located about 275 million light-years from Earth. In addition to being a well-defined spiral galaxy, MCG-01-24-014 has an extremely energetic core known as an active galactic nucleus (AGN) and is categorized as a Type-2 Seyfert galaxy. Seyfert galaxies, along with quasars, host one of the most common subclasses of AGN. While the precise categorization of AGNs is nuanced, Seyfert galaxies tend to be relatively nearby and their central AGN does not outshine its host, while quasars are very distant AGNs with incredible luminosities that outshine their host galaxies.

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Researchers have analyzed more than one million galaxies to explore primordial fluctuations that seeded the formation of the structure of the entire universe.

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Tiny things matter -- for instance, one amino acid can completely alter the architecture of the cell. Researchers have now investigated the structure and mechanics of the main component of the cytoskeleton of the cell: a protein known as actin. Actin is found in all living cells where it has a range of important functions -- from muscle contraction to cell signalling and cell shape. This protein comes in two different varieties termed 'isoforms', which are known as gamma actin and beta actin.

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At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -- but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage. Jellyfish, along with other cnidarians such as corals and sea anemones, exhibit high regeneration abilities, but how they form the critical blastema has remained a mystery until now.

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Researchers mapped how the measles virus mutated and spread in the brain of a person who succumbed to a rare, lethal brain disease. New cases of this disease, which is a complication of the measles virus, may occur as measles reemerges among the unvaccinated, say researchers.

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Analysis of organic compounds -- called polycyclic aromatic hydrocarbons (PAHs) -- extracted from the Ryugu asteroid and Murchison meteorite has found that certain PAHs likely formed in the cold areas of space between stars rather than in hot regions near stars as was previously thought. The findings open new possibilities for studying life beyond Earth and the chemistry of objects in space.

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Scientists reveal how G protein-coupled receptors, major therapeutic drug targets, decode critical properties of their ligands.