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Categories: Biology: Biotechnology, Space: Astrophysics
Published Microbial comics: RNA as a common language, presented in extracellular speech-bubbles
(via sciencedaily.com) Original source Decoding the conversations between microbes of hypersaline environments reveals deep insights into the origins of complex life.
Published Human stem cells coaxed to mimic the very early central nervous system
(via sciencedaily.com) Original source The first stem cell culture method that produces a full model of the early stages of the human central nervous system has been developed by a team of engineers and biologists.
Published Cutting-edge 'protein lawnmower' created
(via sciencedaily.com) Original source Scientists have designed the first synthetic protein-based motor which harnesses biological reactions to fuel and propel itself. 'Imagine if a Roomba could be powered only by the dirt it picks up,' says one of the authors of the study. The motor uses the digestive enzyme trypsin to cut the peptides and convert them into the energy it needs to propel itself.
Published Blindness from some inherited eye diseases may be caused by gut bacteria
(via sciencedaily.com) Original source Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice.
Published The small intestine adapt its size according to nutrient intake
(via sciencedaily.com) Original source Resizing of the intestine is a highly conserved strategy employed by a wide range of organisms to cope with fluctuation in nutrient availability. Nevertheless, very little is known about the mechanisms and signals underlying nutrient-mediated gut resizing. New research has identified one of the signaling pathways implicated in this process.
Published Biomolecular condensates -- regulatory hubs for plant iron supply
(via sciencedaily.com) Original source Iron is a micronutrient for plants. Biologists now show that regulatory proteins for iron uptake behave particularly dynamically in the cell nucleus when the cells are exposed to blue light -- an important signal for plant growth. They found that the initially homogeneously distributed proteins relocated together into 'biomolecular condensates' in the cell nucleus shortly after this exposure.
Published Ribosomes: Molecular wedge assists recycling
(via sciencedaily.com) Original source Researchers reveal how cells regenerate protein factories at endoplasmic reticulum.
Published Compound vital for all life likely played a role in life's origin
(via sciencedaily.com) Original source A chemical compound essential to all living things has been synthesized in a lab in conditions that could have occurred on early Earth, suggesting it played a role at the outset of life.
Published Copies of antibiotic resistance genes greatly elevated in humans and livestock
(via sciencedaily.com) Original source Researchers have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens. Bacteria exposed to higher levels of antibiotics often harbor multiple identical copies of protective antibiotic resistance genes which are linked to 'jumping genes' that can move from strain to strain. Duplicate genes provide a mechanism for resistance to spread and enable evolving resistance to new drugs.
Published Webb finds evidence for neutron star at heart of young supernova remnant
(via sciencedaily.com) Original source NASA's James Webb Space Telescope has found the best evidence yet for emission from a neutron star at the site of a recently observed supernova. The supernova, known as SN 1987A, was a core-collapse supernova, meaning the compacted remains at its core formed either a neutron star or a black hole. Evidence for such a compact object has long been sought, and while indirect evidence for the presence of a neutron star has previously been found, this is the first time that the effects of high-energy emission from the probable young neutron star have been detected.
Published A new beginning: The search for more temperate Tatooines
(via sciencedaily.com) Original source Luke Skywalker's childhood might have been slightly less harsh if he'd grown up on a more temperate Tatooine -- like the ones identified in a new study. According to the study's authors, there are more climate-friendly planets in binary star systems -- in other words, those with two suns -- than previously known. And, they say, it may be a sign that, at least in some ways, the universe leans in the direction of orderly alignment rather than chaotic misalignment.
Published Damage to cell membranes causes cell aging
(via sciencedaily.com) Original source Researchers have discovered that damage to the cell membrane promotes cellular senescence, or cell aging.
Published Brightest and fastest-growing: Astronomers identify record-breaking quasar
(via sciencedaily.com) Original source Astronomers have characterized a bright quasar, finding it to be not only the brightest of its kind, but also the most luminous object ever observed. Quasars are the bright cores of distant galaxies and they are powered by supermassive black holes. The black hole in this record-breaking quasar is growing in mass by the equivalent of one Sun per day, making it the fastest-growing black hole to date.
Published Scientists discover link between leaky gut and accelerated biological aging
(via sciencedaily.com) Original source A professor has demonstrated a connection between viral damage to the gut and premature biological aging.
Published An awkward family reunion: Sea monsters are our cousins
(via sciencedaily.com) Original source The sea lamprey, a 500-million-year-old animal with a sharp-toothed suction cup for a mouth, is the thing of nightmares. A new study discovered that the hindbrain -- the part of the brain controlling vital functions like blood pressure and heart rate -- of both sea lampreys and humans is built using an extraordinarily similar molecular and genetic toolkit.
Published Compounds in female ginseng could lead to new osteoporosis treatments
(via sciencedaily.com) Original source With ever-increasing life expectancy comes the challenge of treating age-related disorders such as osteoporosis. Although there are effective drugs for treating this metabolic bone disease, they can be expensive and have side effects, limiting their availability to some people. In the search for alternative drug candidates, researchers have discovered and fully replicated a compound from a botanical source, female ginseng, that had potent anti-osteoporotic activity in cellular tests.
Published New system triggers cellular waste disposal
(via sciencedaily.com) Original source Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers have previously demonstrated the efficacy of this approach through two distinct methods. Now they unveil a third system capable of targeting and disposing of previously inaccessible proteins.
Published Detecting pathogens faster and more accurately by melting DNA
(via sciencedaily.com) Original source A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
Published Black hole at center of the Milky Way resembles a football
(via sciencedaily.com) Original source The supermassive black hole in the center of the Milky Way is spinning so quickly it is warping the spacetime surrounding it into a shape that can look like a football, according to a new study. That football shape suggests the black hole is spinning at a substantial speed, which researchers estimated to be about 60% of its potential limit.
Published Breakthrough in developing the PD-1-enhanced DNA vaccine for over 6-year cART-free AIDS prevention and virologic control
(via sciencedaily.com) Original source Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supporting evidence that the PD-1-enhanced DNA vaccine strategy holds promise as a third-generation DNA vaccine for AIDS prevention and immunotherapy.