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Categories: Biology: Biotechnology, Space: Astrophysics
Published When inequality is more than 'skin-deep': Social status leaves traces in the epigenome of spotted hyenas in Tanzania
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A research consortium provides evidence that social behavior and social status are reflected at the molecular level of gene activation (epigenome) in juvenile and adult free-ranging spotted hyenas. They analyzed non-invasively collected gut epithelium samples from both high-ranking and low-ranking female hyenas and showed that rank differences were associated with epigenetic signatures of social inequality, i.e., the pattern of activation or switching off of genes that regulate important physiological processes such as energy conversion and immune response in several genome regions.
Published How the Crimean-Congo hemorrhagic fever virus enters our cells
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Researchers have identified how the tick-borne Crimean-Congo haemorrhagic fever virus enters our cells. The results are an important step in the development of drugs against the deadly disease.
Published Genomic research may help explain cancer resistance in Tasmanian devils
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Through DNA sequencing of Tasmanian devils and their tumors, researchers have tracked the genomic interactions between the animals and the cancer.
Published Researchers discover key gene for toxic alkaloid in barley
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Barley is one of the most important cereal crops on a global scale. Many barley cultivars produce a toxic alkaloid called gramine that affects the suitability of barley as fodder, but also helps to protect barley from pathogens. So far, the potential of manipulating gramine levels has not been harnessed for plant breeding, because the genetic basis of gramine production has been unresolved. Research groups now disclose the complete biosynthetic pathway of gramine and demonstrate how gramine biosynthesis can be introduced into model organisms or removed from barley.
Published Unlocking supernova stardust secrets
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New research has discovered a rare dust particle trapped in an ancient extra-terrestrial meteorite that was formed by a star other than our sun.
Published Connecting the dots to shape growth forces
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Branching patterns are prevalent in our natural environment and the human body, such as in the lungs and kidneys. For example, specific genes that express growth factor proteins are known to influence the development of the lungs' complex branches. Researchers have unveiled a regulatory system linking signal, force, and shape in mouse lung structure development. The team recognized that the signal protein ERK plays an active role in causing growing lung tissue to curve.
Published ALMA finds new molecular signposts in starburst galaxy
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The ALMA radio telescope has detected more than 100 molecular species, including many indicative of different star formation and evolution processes, in a galaxy where stars are forming much more actively than in the Milky Way. This is far more molecules than were found in previous studies. Now the team will try to apply this knowledge to other galaxies.
Published Synaptic protein change during development offers clues on evolution and disease
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An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The findings offer first insights into the mechanism behind synaptic development and open up routes for research on possible treatments.
Published A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis
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Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of anti-microbial medications to kill tuberculosis bacteria residing in the lungs.
Published Astronomers conduct first search for forming planets with new space telescope
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Planets form in disks of dust and gas called protoplanetary disks that whirl around a central protostar during its final assembly.
Published Persistent hiccups in a far-off galaxy draw astronomers to new black hole behavior
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Astronomers have found that a previously quiet black hole, which sits at the center of a galaxy about 800 million light years away, has suddenly erupted, giving off plumes of gas every 8.5 days before settling back to its normal, quiet state.
Published Sweet success: Sugarcane's complex genetic code cracked
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Scientists created a highly accurate reference genome for one of the most important modern crops and found a rare example of how genes confer disease resistance in plants. Exploring sugarcane's genetic code could help researchers develop more resilient and productive crops, with implications for both sugar production and biofuels.
Published Scientists extract genetic secrets from 4,000-year-old teeth to illuminate the impact of changing human diets over the centuries
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Researchers have recovered remarkably preserved microbiomes from two teeth dating back 4,000 years, found in an Irish limestone cave. Genetic analyses of these microbiomes reveal major changes in the oral microenvironment from the Bronze Age to today. The teeth both belonged to the same male individual and also provided a snapshot of his oral health.
Published New technique for predicting protein dynamics may prove big breakthrough for drug discovery
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Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple protein configurations to advance understanding of protein dynamics and functions.
Published New enzymatic cocktail can kill tuberculosis-causing mycobacteria
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An enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.
Published Astronomers unveil strong magnetic fields spiraling at the edge of Milky Way's central black hole
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A new image from the Event Horizon Telescope (EHT) collaboration has uncovered strong and organized magnetic fields spiraling from the edge of the supermassive black hole Sagittarius A* (Sgr A*). Seen in polarized light for the first time, this new view of the monster lurking at the heart of the Milky Way Galaxy has revealed a magnetic field structure strikingly similar to that of the black hole at the center of the M87 galaxy, suggesting that strong magnetic fields may be common to all black holes.
Published Old immune systems revitalized in mouse study, improving vaccine response
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Those with aging immune systems struggle to fight off novel viruses and respond weakly to vaccination. Researchers were able to revitalize the immune system in mice.
Published 'Cosmic cannibals' expel jets into space at 40 percent the speed of light
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Astronomers have measured the speed of fast-moving jets in space, crucial to star formation and the distribution of elements needed for life. The jets of matter, expelled by stars deemed 'cosmic cannibals', were measured to travel at over one-third of the speed of light -- thanks to a groundbreaking new experiment.
Published Sleeping supermassive black holes awakened briefly by shredded stars
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Astronomers have concluded that an obscure class of galaxies known as Compact Symmetric Objects, or CSOs, are not young as previously thought but rather lead relatively short lives.
Published Researchers show that introduced tardigrade proteins can slow metabolism in human cells
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Tardigrade proteins are potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.